Compile Data Set for Download or QSAR
Report error Found 16 Enz. Inhib. hit(s) with all data for entry = 50039824
TargetProstaglandin G/H synthase 1(Human)
Rheinische Friedrich-Wilhelms-Universit£T

Curated by ChEMBL
LigandPNGBDBM13066({2-[(2,6-dichlorophenyl)amino]phenyl}acetic acid |...)
Affinity DataIC50: 3nMAssay Description:Inhibition of COX1More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProstaglandin G/H synthase 2(Human)
Rheinische Friedrich-Wilhelms-Universit£T

Curated by ChEMBL
LigandPNGBDBM13066({2-[(2,6-dichlorophenyl)amino]phenyl}acetic acid |...)
Affinity DataIC50: 5nMAssay Description:Inhibition of COX2More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetVascular endothelial growth factor receptor 2(Human)
Rheinische Friedrich-Wilhelms-Universit£T

Curated by ChEMBL
LigandPNGBDBM5380(N-(3,5-dimethylphenyl)-4-(2-phenyl-1H-imidazol-1-y...)
Affinity DataIC50: 6nMAssay Description:Antagonist activity at VEGFR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Rheinische Friedrich-Wilhelms-Universit£T

Curated by ChEMBL
LigandPNGBDBM50207446(2-(2-(2-chloro-6-fluorophenylamino)-5-methylphenyl...)
Affinity DataIC50: 7nMAssay Description:Inhibition of COX1More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Rheinische Friedrich-Wilhelms-Universit£T

Curated by ChEMBL
LigandPNGBDBM50384799(CHEMBL2037483)
Affinity DataIC50: 20nMAssay Description:Inhibition of COX1More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Rheinische Friedrich-Wilhelms-Universit£T

Curated by ChEMBL
LigandPNGBDBM5400(N-(3,5-dimethylphenyl)-4-[2-(pyridin-3-yl)-1H-imid...)
Affinity DataIC50: 2.39E+3nMAssay Description:Antagonist activity at VEGFR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetProcathepsin L(Human)
Rheinische Friedrich-Wilhelms-Universit£T

Curated by ChEMBL
LigandPNGBDBM19828(racemic mixture | (1R,2R)-2-{[(3-chlorophenyl)sulf...)
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of cathepsin LMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetCathepsin B(Human)
Rheinische Friedrich-Wilhelms-Universit£T

Curated by ChEMBL
LigandPNGBDBM19817(racemic mixture | (1R,2R)-N-(cyanomethyl)-2-[(phen...)
Affinity DataIC50: 5.30E+3nMAssay Description:Inhibition of cathepsin BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Rheinische Friedrich-Wilhelms-Universit£T

Curated by ChEMBL
LigandPNGBDBM50207446(2-(2-(2-chloro-6-fluorophenylamino)-5-methylphenyl...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of COX2More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProcathepsin L(Human)
Rheinische Friedrich-Wilhelms-Universit£T

Curated by ChEMBL
LigandPNGBDBM19817(racemic mixture | (1R,2R)-N-(cyanomethyl)-2-[(phen...)
Affinity DataIC50: 2.60E+4nMAssay Description:Inhibition of cathepsin LMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Rheinische Friedrich-Wilhelms-Universit£T

Curated by ChEMBL
LigandPNGBDBM50049661(3''''-Fluoro-4''''-methoxy-[1,1'';2'',1'''']terphe...)
Affinity DataIC50: 7.16E+4nMAssay Description:Inhibition of COX1More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetCathepsin B(Human)
Rheinische Friedrich-Wilhelms-Universit£T

Curated by ChEMBL
LigandPNGBDBM19828(racemic mixture | (1R,2R)-2-{[(3-chlorophenyl)sulf...)
Affinity DataIC50: 1.02E+5nMAssay Description:Inhibition of cathepsin BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Rheinische Friedrich-Wilhelms-Universit£T

Curated by ChEMBL
LigandPNGBDBM50163460(2-Amino-6-(2-hydroxy-ethylsulfanyl)-4-(3-trifluoro...)
Affinity DataKi:  14.1nMAssay Description:Antagonist activity at adenosine A1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Rheinische Friedrich-Wilhelms-Universit£T

Curated by ChEMBL
LigandPNGBDBM50163452(2-Amino-4-(3-fluoro-phenyl)-6-(2-hydroxy-ethylsulf...)
Affinity DataKi:  39.8nMAssay Description:Antagonist activity at adenosine A1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Rheinische Friedrich-Wilhelms-Universit£T

Curated by ChEMBL
LigandPNGBDBM50163453(2-Amino-4-(3-difluoromethoxy-phenyl)-6-(2-hydroxy-...)
Affinity DataKi:  39.8nMAssay Description:Antagonist activity at adenosine A1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Rheinische Friedrich-Wilhelms-Universit£T

Curated by ChEMBL
LigandPNGBDBM50163462(2-Amino-6-(2-hydroxy-ethylsulfanyl)-4-m-tolyl-pyri...)
Affinity DataKi:  81.3nMAssay Description:Antagonist activity at adenosine A1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed