Compile Data Set for Download or QSAR
Report error Found 20 Enz. Inhib. hit(s) with all data for entry = 50034424
TargetMAP kinase-activated protein kinase 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50362177(CHEMBL1938689)
Affinity DataEC50:  2.50E+3nMAssay Description:Inhibition of MK2-mediated HSP27 phosphorylation at Ser78 in LPS-stimulated human THP-1 cells pre-incubated for 60 mins before LPS treatment measured...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMAP kinase-activated protein kinase 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50362175(CHEMBL1938687)
Affinity DataEC50:  260nMAssay Description:Inhibition of MK2-mediated HSP27 phosphorylation at Ser78 in LPS-stimulated human THP-1 cells pre-incubated for 60 mins before LPS treatment measured...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMAP kinase-activated protein kinase 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50362174(CHEMBL1938686)
Affinity DataEC50:  2.10E+3nMAssay Description:Inhibition of MK2-mediated HSP27 phosphorylation at Ser78 in LPS-stimulated human THP-1 cells pre-incubated for 60 mins before LPS treatment measured...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMAP kinase-activated protein kinase 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50362173(CHEMBL1938685)
Affinity DataEC50:  260nMAssay Description:Inhibition of MK2-mediated HSP27 phosphorylation at Ser78 in LPS-stimulated human THP-1 cells pre-incubated for 60 mins before LPS treatment measured...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMAP kinase-activated protein kinase 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50362169(CHEMBL1938680)
Affinity DataEC50:  2.00E+3nMAssay Description:Inhibition of MK2-mediated HSP27 phosphorylation at Ser78 in LPS-stimulated human THP-1 cells pre-incubated for 60 mins before LPS treatment measured...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMAP kinase-activated protein kinase 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50362106(CHEMBL1938681)
Affinity DataEC50:  350nMAssay Description:Inhibition of MK2-mediated HSP27 phosphorylation at Ser78 in LPS-stimulated human THP-1 cells pre-incubated for 60 mins before LPS treatment measured...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMAP kinase-activated protein kinase 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50362172(CHEMBL1938684)
Affinity DataEC50:  1.50E+3nMAssay Description:Inhibition of MK2-mediated HSP27 phosphorylation at Ser78 in LPS-stimulated human THP-1 cells pre-incubated for 60 mins before LPS treatment measured...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMAP kinase-activated protein kinase 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50362173(CHEMBL1938685)
Affinity DataIC50: 2.90nMAssay Description:Inhibition of MK2 using TAMRA-labeled peptide as substrate pre-incubated for 30 mins prior substrate addition measured after 30 mins incubation in da...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMAP kinase-activated protein kinase 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50362175(CHEMBL1938687)
Affinity DataIC50: 3.80nMAssay Description:Inhibition of MK2 using TAMRA-labeled peptide as substrate pre-incubated for 30 mins prior substrate addition measured after 30 mins incubation in da...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMAP kinase-activated protein kinase 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50362172(CHEMBL1938684)
Affinity DataIC50: 7nMAssay Description:Inhibition of MK2 using TAMRA-labeled peptide as substrate pre-incubated for 30 mins prior substrate addition measured after 30 mins incubation in da...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMAP kinase-activated protein kinase 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50362177(CHEMBL1938689)
Affinity DataIC50: 9.20nMAssay Description:Inhibition of MK2 using TAMRA-labeled peptide as substrate pre-incubated for 30 mins prior substrate addition measured after 30 mins incubation in da...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMAP kinase-activated protein kinase 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50362174(CHEMBL1938686)
Affinity DataIC50: 9.30nMAssay Description:Inhibition of MK2 using TAMRA-labeled peptide as substrate pre-incubated for 30 mins prior substrate addition measured after 30 mins incubation in da...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMAP kinase-activated protein kinase 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50362176(CHEMBL1938688)
Affinity DataIC50: 15nMAssay Description:Inhibition of MK2 using TAMRA-labeled peptide as substrate pre-incubated for 30 mins prior substrate addition measured after 30 mins incubation in da...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMAP kinase-activated protein kinase 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50362179(CHEMBL1938691)
Affinity DataIC50: 18nMAssay Description:Inhibition of MK2 using TAMRA-labeled peptide as substrate pre-incubated for 30 mins prior substrate addition measured after 30 mins incubation in da...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMAP kinase-activated protein kinase 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50362170(CHEMBL1938682)
Affinity DataIC50: 96nMAssay Description:Inhibition of MK2 using TAMRA-labeled peptide as substrate pre-incubated for 30 mins prior substrate addition measured after 30 mins incubation in da...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMAP kinase-activated protein kinase 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50362106(CHEMBL1938681)
Affinity DataIC50: 110nMAssay Description:Inhibition of MK2 using TAMRA-labeled peptide as substrate pre-incubated for 30 mins prior substrate addition measured after 30 mins incubation in da...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMAP kinase-activated protein kinase 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50362180(CHEMBL1938692)
Affinity DataIC50: 110nMAssay Description:Inhibition of MK2 using TAMRA-labeled peptide as substrate pre-incubated for 30 mins prior substrate addition measured after 30 mins incubation in da...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMAP kinase-activated protein kinase 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50362171(CHEMBL1938683)
Affinity DataIC50: 110nMAssay Description:Inhibition of MK2 using TAMRA-labeled peptide as substrate pre-incubated for 30 mins prior substrate addition measured after 30 mins incubation in da...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMAP kinase-activated protein kinase 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50362178(CHEMBL1938690)
Affinity DataIC50: 880nMAssay Description:Inhibition of MK2 using TAMRA-labeled peptide as substrate pre-incubated for 30 mins prior substrate addition measured after 30 mins incubation in da...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMAP kinase-activated protein kinase 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50362169(CHEMBL1938680)
Affinity DataIC50: 5.50E+3nMAssay Description:Inhibition of MK2 using TAMRA-labeled peptide as substrate pre-incubated for 30 mins prior substrate addition measured after 30 mins incubation in da...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed