Compile Data Set for Download or QSAR
Report error Found 42 Enz. Inhib. hit(s) with all data for entry = 50034238
TargetAmine oxidase [flavin-containing] A(Rat)
Universitat Aut£Noma De Barcelona

Curated by ChEMBL
LigandPNGBDBM50359391(CHEMBL1929421)
Affinity DataIC50: 5.20nMAssay Description:Inhibition of rat liver mitochondrial MAO-A using [14C]-5-hydroxytryptamine after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Universitat Aut£Noma De Barcelona

Curated by ChEMBL
LigandPNGBDBM8960(2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2...)
Affinity DataIC50: 6.70nMAssay Description:Inhibition of Electrophorus electricus AchE using acetylthiocholine iodide as substrate preincubated for 10 mins measured after 15 mins of substrate ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmine oxidase [flavin-containing] A(Rat)
Universitat Aut£Noma De Barcelona

Curated by ChEMBL
LigandPNGBDBM50359396(CHEMBL1929420 | US8999994, 5)
Affinity DataIC50: 6.70nMAssay Description:Inhibition of rat liver mitochondrial MAO-A using [14C]-5-hydroxytryptamine after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmine oxidase [flavin-containing] A(Rat)
Universitat Aut£Noma De Barcelona

Curated by ChEMBL
LigandPNGBDBM50359395(CHEMBL1929422)
Affinity DataIC50: 10nMAssay Description:Inhibition of rat liver mitochondrial MAO-A using [14C]-5-hydroxytryptamine after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmine oxidase [flavin-containing] A(Rat)
Universitat Aut£Noma De Barcelona

Curated by ChEMBL
LigandPNGBDBM50359392(CHEMBL1929424 | US8999994, 3)
Affinity DataIC50: 31nMAssay Description:Inhibition of rat liver mitochondrial MAO-A using [14C]-5-hydroxytryptamine after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCholinesterase(Human)
Universitat Aut£Noma De Barcelona

Curated by ChEMBL
LigandPNGBDBM8961(CHEMBL95 | Cognex | cid_1935 | CHEMBL1337960 | 1,2...)
Affinity DataIC50: 36nMAssay Description:Inhibition of human serum BuchE using butyrylthiocholine iodide as substrate preincubated for 10 mins measured after 15 mins of substrate addition by...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetAmine oxidase [flavin-containing] B(Rat)
Universitat Aut£Noma De Barcelona

Curated by ChEMBL
LigandPNGBDBM50359391(CHEMBL1929421)
Affinity DataIC50: 43nMAssay Description:Inhibition of rat liver mitochondrial MAO-B using [14C]-phenylethylamine after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmine oxidase [flavin-containing] B(Rat)
Universitat Aut£Noma De Barcelona

Curated by ChEMBL
LigandPNGBDBM50359390(CHEMBL2022924 | CHEMBL1929418)
Affinity DataIC50: 63nMAssay Description:Inhibition of rat liver mitochondrial MAO-B using [14C]-phenylethylamine after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmine oxidase [flavin-containing] A(Rat)
Universitat Aut£Noma De Barcelona

Curated by ChEMBL
LigandPNGBDBM50359393(CHEMBL1926712 | US8999994, 2)
Affinity DataIC50: 65nMAssay Description:Inhibition of rat liver mitochondrial MAO-A using [14C]-5-hydroxytryptamine after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmine oxidase [flavin-containing] A(Rat)
Universitat Aut£Noma De Barcelona

Curated by ChEMBL
LigandPNGBDBM50359397(CHEMBL1929419 | US8999994, 4)
Affinity DataIC50: 82nMAssay Description:Inhibition of rat liver mitochondrial MAO-A using [14C]-5-hydroxytryptamine after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmine oxidase [flavin-containing] A(Rat)
Universitat Aut£Noma De Barcelona

Curated by ChEMBL
LigandPNGBDBM50359390(CHEMBL2022924 | CHEMBL1929418)
Affinity DataIC50: 100nMAssay Description:Inhibition of rat liver mitochondrial MAO-A using [14C]-5-hydroxytryptamine after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Human)
Universitat Aut£Noma De Barcelona

Curated by ChEMBL
LigandPNGBDBM8961(CHEMBL95 | Cognex | cid_1935 | CHEMBL1337960 | 1,2...)
Affinity DataIC50: 122nMAssay Description:Inhibition of cerebral human recombinant AchE expressed in HEK293 cells using acetylthiocholine iodide as substrate preincubated for 10 mins measured...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetAmine oxidase [flavin-containing] B(Rat)
Universitat Aut£Noma De Barcelona

Curated by ChEMBL
LigandPNGBDBM50359396(CHEMBL1929420 | US8999994, 5)
Affinity DataIC50: 130nMAssay Description:Inhibition of rat liver mitochondrial MAO-B using [14C]-phenylethylamine after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmine oxidase [flavin-containing] A(Rat)
Universitat Aut£Noma De Barcelona

Curated by ChEMBL
LigandPNGBDBM50359394(CHEMBL1929423 | US8999994, 1)
Affinity DataIC50: 140nMAssay Description:Inhibition of rat liver mitochondrial MAO-A using [14C]-5-hydroxytryptamine after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Universitat Aut£Noma De Barcelona

Curated by ChEMBL
LigandPNGBDBM50359395(CHEMBL1929422)
Affinity DataIC50: 260nMAssay Description:Inhibition of Electrophorus electricus AchE using acetylthiocholine iodide as substrate preincubated for 10 mins measured after 15 mins of substrate ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Universitat Aut£Noma De Barcelona

Curated by ChEMBL
LigandPNGBDBM50359397(CHEMBL1929419 | US8999994, 4)
Affinity DataIC50: 310nMAssay Description:Inhibition of Electrophorus electricus AchE using acetylthiocholine iodide as substrate preincubated for 10 mins measured after 15 mins of substrate ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Universitat Aut£Noma De Barcelona

Curated by ChEMBL
LigandPNGBDBM50359391(CHEMBL1929421)
Affinity DataIC50: 350nMAssay Description:Inhibition of Electrophorus electricus AchE using acetylthiocholine iodide as substrate preincubated for 10 mins measured after 15 mins of substrate ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Human)
Universitat Aut£Noma De Barcelona

Curated by ChEMBL
LigandPNGBDBM50359391(CHEMBL1929421)
Affinity DataIC50: 380nMAssay Description:Inhibition of cerebral human recombinant AchE expressed in HEK293 cells using acetylthiocholine iodide as substrate preincubated for 10 mins measured...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Universitat Aut£Noma De Barcelona

Curated by ChEMBL
LigandPNGBDBM50359396(CHEMBL1929420 | US8999994, 5)
Affinity DataIC50: 420nMAssay Description:Inhibition of Electrophorus electricus AchE using acetylthiocholine iodide as substrate preincubated for 10 mins measured after 15 mins of substrate ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCholinesterase(Horse)
Universitat Aut£Noma De Barcelona

Curated by ChEMBL
LigandPNGBDBM50359391(CHEMBL1929421)
Affinity DataIC50: 460nMAssay Description:Inhibition of equine serum BuchE using butyrylthiocholine iodide as substrate preincubated for 10 mins measured after 15 mins of substrate addition b...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmine oxidase [flavin-containing] B(Rat)
Universitat Aut£Noma De Barcelona

Curated by ChEMBL
LigandPNGBDBM50359397(CHEMBL1929419 | US8999994, 4)
Affinity DataIC50: 750nMAssay Description:Inhibition of rat liver mitochondrial MAO-B using [14C]-phenylethylamine after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCholinesterase(Horse)
Universitat Aut£Noma De Barcelona

Curated by ChEMBL
LigandPNGBDBM50359394(CHEMBL1929423 | US8999994, 1)
Affinity DataIC50: 800nMAssay Description:Inhibition of equine serum BuchE using butyrylthiocholine iodide as substrate preincubated for 10 mins measured after 15 mins of substrate addition b...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCholinesterase(Horse)
Universitat Aut£Noma De Barcelona

Curated by ChEMBL
LigandPNGBDBM50359395(CHEMBL1929422)
Affinity DataIC50: 990nMAssay Description:Inhibition of equine serum BuchE using butyrylthiocholine iodide as substrate preincubated for 10 mins measured after 15 mins of substrate addition b...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCholinesterase(Horse)
Universitat Aut£Noma De Barcelona

Curated by ChEMBL
LigandPNGBDBM50359397(CHEMBL1929419 | US8999994, 4)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of equine serum BuchE using butyrylthiocholine iodide as substrate preincubated for 10 mins measured after 15 mins of substrate addition b...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmine oxidase [flavin-containing] B(Rat)
Universitat Aut£Noma De Barcelona

Curated by ChEMBL
LigandPNGBDBM50359394(CHEMBL1929423 | US8999994, 1)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of rat liver mitochondrial MAO-B using [14C]-phenylethylamine after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmine oxidase [flavin-containing] B(Rat)
Universitat Aut£Noma De Barcelona

Curated by ChEMBL
LigandPNGBDBM50359392(CHEMBL1929424 | US8999994, 3)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of rat liver mitochondrial MAO-B using [14C]-phenylethylamine after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCholinesterase(Human)
Universitat Aut£Noma De Barcelona

Curated by ChEMBL
LigandPNGBDBM50359391(CHEMBL1929421)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of human serum BuchE using butyrylthiocholine iodide as substrate preincubated for 10 mins measured after 15 mins of substrate addition by...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCholinesterase(Horse)
Universitat Aut£Noma De Barcelona

Curated by ChEMBL
LigandPNGBDBM50359396(CHEMBL1929420 | US8999994, 5)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of equine serum BuchE using butyrylthiocholine iodide as substrate preincubated for 10 mins measured after 15 mins of substrate addition b...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCholinesterase(Horse)
Universitat Aut£Noma De Barcelona

Curated by ChEMBL
LigandPNGBDBM50359393(CHEMBL1926712 | US8999994, 2)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of equine serum BuchE using butyrylthiocholine iodide as substrate preincubated for 10 mins measured after 15 mins of substrate addition b...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmine oxidase [flavin-containing] B(Rat)
Universitat Aut£Noma De Barcelona

Curated by ChEMBL
LigandPNGBDBM50359395(CHEMBL1929422)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of rat liver mitochondrial MAO-B using [14C]-phenylethylamine after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCholinesterase(Horse)
Universitat Aut£Noma De Barcelona

Curated by ChEMBL
LigandPNGBDBM8960(2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2...)
Affinity DataIC50: 7.40E+3nMAssay Description:Inhibition of equine serum BuchE using butyrylthiocholine iodide as substrate preincubated for 10 mins measured after 15 mins of substrate addition b...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCholinesterase(Horse)
Universitat Aut£Noma De Barcelona

Curated by ChEMBL
LigandPNGBDBM50359392(CHEMBL1929424 | US8999994, 3)
Affinity DataIC50: 7.60E+3nMAssay Description:Inhibition of equine serum BuchE using butyrylthiocholine iodide as substrate preincubated for 10 mins measured after 15 mins of substrate addition b...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmine oxidase [flavin-containing] B(Rat)
Universitat Aut£Noma De Barcelona

Curated by ChEMBL
LigandPNGBDBM50359393(CHEMBL1926712 | US8999994, 2)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of rat liver mitochondrial MAO-B using [14C]-phenylethylamine after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmine oxidase [flavin-containing] B(Rat)
Universitat Aut£Noma De Barcelona

Curated by ChEMBL
LigandPNGBDBM8960(2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2...)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of rat liver mitochondrial MAO-B using [14C]-phenylethylamine after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Universitat Aut£Noma De Barcelona

Curated by ChEMBL
LigandPNGBDBM50359393(CHEMBL1926712 | US8999994, 2)
Affinity DataIC50: 1.81E+4nMAssay Description:Inhibition of Electrophorus electricus AchE using acetylthiocholine iodide as substrate preincubated for 10 mins measured after 15 mins of substrate ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Universitat Aut£Noma De Barcelona

Curated by ChEMBL
LigandPNGBDBM50359390(CHEMBL2022924 | CHEMBL1929418)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Electrophorus electricus AchE using acetylthiocholine iodide as substrate preincubated for 10 mins measured after 15 mins of substrate ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Universitat Aut£Noma De Barcelona

Curated by ChEMBL
LigandPNGBDBM50359394(CHEMBL1929423 | US8999994, 1)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Electrophorus electricus AchE using acetylthiocholine iodide as substrate preincubated for 10 mins measured after 15 mins of substrate ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Universitat Aut£Noma De Barcelona

Curated by ChEMBL
LigandPNGBDBM50359392(CHEMBL1929424 | US8999994, 3)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Electrophorus electricus AchE using acetylthiocholine iodide as substrate preincubated for 10 mins measured after 15 mins of substrate ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCholinesterase(Horse)
Universitat Aut£Noma De Barcelona

Curated by ChEMBL
LigandPNGBDBM50359390(CHEMBL2022924 | CHEMBL1929418)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of equine serum BuchE using butyrylthiocholine iodide as substrate preincubated for 10 mins measured after 15 mins of substrate addition b...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmine oxidase [flavin-containing] A(Rat)
Universitat Aut£Noma De Barcelona

Curated by ChEMBL
LigandPNGBDBM8960(2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2...)
Affinity DataIC50: 8.50E+5nMAssay Description:Inhibition of rat liver mitochondrial MAO-A using [14C]-5-hydroxytryptamine after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmine oxidase [flavin-containing] B(Rat)
Universitat Aut£Noma De Barcelona

Curated by ChEMBL
LigandPNGBDBM50359391(CHEMBL1929421)
Affinity DataKi:  11nMAssay Description:Non-competitive inhibition of rat liver mitochondrial MAO-B using phenylethylamine as substrate by Line-Weaver Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Universitat Aut£Noma De Barcelona

Curated by ChEMBL
LigandPNGBDBM50359391(CHEMBL1929421)
Affinity DataKi:  149nMAssay Description:Mixed type inhibition of Electrophorus electricus AchE using acetylthiocholine as substrate by Line-Weaver Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed