Compile Data Set for Download or QSAR
Report error Found 13 Enz. Inhib. hit(s) with all data for entry = 50004647
TargetAmyloid-beta precursor protein(Human)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50481120(Flutemetamol | [3H]-Flutemetamol)
Affinity DataKi:  0.740nMAssay Description:Displacement of [18F]-amyvid from amyloid-beta aggregates in alzheimer's disease patient brain homogenates after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetAmyloid-beta precursor protein(Human)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50129793(N-methyl-[11C]2-(40-methylaminophenyl)-6-hydroxy b...)
Affinity DataKi:  0.870nMAssay Description:Displacement of [18F]-amyvid from amyloid-beta aggregates in alzheimer's disease patient brain homogenates after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetAmyloid-beta precursor protein(Human)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50122787(4-(6-iodoimidazo[1,2-a]pyridin-2-yl)-N,N-dimethyla...)
Affinity DataKi:  1.30nMAssay Description:Displacement of [18F]-amyvid from amyloid-beta aggregates in alzheimer's disease patient brain homogenates after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetAmyloid-beta precursor protein(Human)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50485236(CHEBI:79033 | BAY-949172 | Florbetaben (18f) | Flo...)
Affinity DataKi:  2.20nMAssay Description:Displacement of [18F]-amyvid from amyloid-beta aggregates in alzheimer's disease patient brain homogenates after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetAmyloid-beta precursor protein(Human)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50485233(AZD-4694 | CHEMBL2042123)
Affinity DataKi:  2.30nMAssay Description:Displacement of [18F]-amyvid from amyloid-beta aggregates in alzheimer's disease patient brain homogenates after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetAmyloid-beta precursor protein(Human)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50484946(CHEBI:66880 | (18F)AV-45 | 18F-AV-45 | AV-45 F-18 ...)
Affinity DataKi:  2.90nMAssay Description:Displacement of [18F]-amyvid from amyloid-beta aggregates in alzheimer's disease patient brain homogenates after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetAmyloid-beta precursor protein(Human)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50173647(4-[(E)-2-(4-Methylamino-phenyl)-vinyl]-phenol | [3...)
Affinity DataKi:  3.20nMAssay Description:Displacement of [18F]-amyvid from amyloid-beta aggregates in alzheimer's disease patient brain homogenates after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetAmyloid-beta precursor protein(Human)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50485234(CHEMBL2042124)
Affinity DataKi:  3.20nMAssay Description:Displacement of [18F]-amyvid from amyloid-beta aggregates in alzheimer's disease patient brain homogenates after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetAmyloid-beta precursor protein(Human)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50485235(CHEMBL2042245)
Affinity DataKi:  3.90nMAssay Description:Displacement of [18F]-amyvid from amyloid-beta aggregates in alzheimer's disease patient brain homogenates after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetAmyloid-beta precursor protein(Human)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50485239(CHEMBL2042125)
Affinity DataKi:  7.70nMAssay Description:Displacement of [18F]-amyvid from amyloid-beta aggregates in alzheimer's disease patient brain homogenates after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetAmyloid-beta precursor protein(Human)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50485237(CHEMBL2042246)
Affinity DataKi:  71nMAssay Description:Displacement of [18F]-amyvid from amyloid-beta aggregates in alzheimer's disease patient brain homogenates after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetAmyloid-beta precursor protein(Human)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50485238(CHEMBL2042247)
Affinity DataKi:  468nMAssay Description:Displacement of [18F]-amyvid from amyloid-beta aggregates in alzheimer's disease patient brain homogenates after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetAmyloid-beta precursor protein(Human)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50485232(CHEMBL2042248)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [18F]-amyvid from amyloid-beta aggregates in alzheimer's disease patient brain homogenates after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed