Compile Data Set for Download or QSAR
Report error Found 180 Enz. Inhib. hit(s) with all data for entry = 50034132
TargetBcl2-associated agonist of cell death(Human)
Cylene Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50357587(CHEMBL1915438)
Affinity DataEC50:  30nMAssay Description:Inhibition of BAD phosphorylation at Ser112 in human MV-4-11 cells assessed as phospho-BAD level after 4 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBcl2-associated agonist of cell death(Human)
Cylene Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50357591(CHEMBL1915442)
Affinity DataEC50:  140nMAssay Description:Inhibition of BAD phosphorylation at Ser112 in human MV-4-11 cells assessed as phospho-BAD level after 4 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBcl2-associated agonist of cell death(Human)
Cylene Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50357594(CHEMBL1915445)
Affinity DataEC50:  90nMAssay Description:Inhibition of BAD phosphorylation at Ser112 in human MV-4-11 cells assessed as phospho-BAD level after 4 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBcl2-associated agonist of cell death(Human)
Cylene Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50357597(CHEMBL1915448)
Affinity DataEC50:  50nMAssay Description:Inhibition of BAD phosphorylation at Ser112 in human MV-4-11 cells assessed as phospho-BAD level after 4 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBcl2-associated agonist of cell death(Human)
Cylene Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50357598(CHEMBL1915449)
Affinity DataEC50:  30nMAssay Description:Inhibition of BAD phosphorylation at Ser112 in human MV-4-11 cells assessed as phospho-BAD level after 4 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBcl2-associated agonist of cell death(Human)
Cylene Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50357599(CHEMBL1915633)
Affinity DataEC50:  1.58E+3nMAssay Description:Inhibition of BAD phosphorylation at Ser112 in human MV-4-11 cells assessed as phospho-BAD level after 4 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBcl2-associated agonist of cell death(Human)
Cylene Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50357602(CHEMBL1915636)
Affinity DataEC50:  530nMAssay Description:Inhibition of BAD phosphorylation at Ser112 in human MV-4-11 cells assessed as phospho-BAD level after 4 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBcl2-associated agonist of cell death(Human)
Cylene Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50357607(CHEMBL1915641)
Affinity DataEC50:  40nMAssay Description:Inhibition of BAD phosphorylation at Ser112 in human MV-4-11 cells assessed as phospho-BAD level after 4 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBcl2-associated agonist of cell death(Human)
Cylene Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50357610(CHEMBL1915644)
Affinity DataEC50:  1.02E+3nMAssay Description:Inhibition of BAD phosphorylation at Ser112 in human MV-4-11 cells assessed as phospho-BAD level after 4 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBcl2-associated agonist of cell death(Human)
Cylene Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50357611(CHEMBL1915645)
Affinity DataEC50:  100nMAssay Description:Inhibition of BAD phosphorylation at Ser112 in human MV-4-11 cells assessed as phospho-BAD level after 4 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBcl2-associated agonist of cell death(Human)
Cylene Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50357612(CHEMBL1915646)
Affinity DataEC50:  210nMAssay Description:Inhibition of BAD phosphorylation at Ser112 in human MV-4-11 cells assessed as phospho-BAD level after 4 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBcl2-associated agonist of cell death(Human)
Cylene Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50357613(CHEMBL1915647)
Affinity DataEC50:  890nMAssay Description:Inhibition of BAD phosphorylation at Ser112 in human MV-4-11 cells assessed as phospho-BAD level after 4 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBcl2-associated agonist of cell death(Human)
Cylene Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50357614(CHEMBL1915648)
Affinity DataEC50:  980nMAssay Description:Inhibition of BAD phosphorylation at Ser112 in human MV-4-11 cells assessed as phospho-BAD level after 4 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBcl2-associated agonist of cell death(Human)
Cylene Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50357616(CHEMBL1915650)
Affinity DataEC50:  200nMAssay Description:Inhibition of BAD phosphorylation at Ser112 in human MV-4-11 cells assessed as phospho-BAD level after 4 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBcl2-associated agonist of cell death(Human)
Cylene Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50357617(CHEMBL1915651)
Affinity DataEC50:  100nMAssay Description:Inhibition of BAD phosphorylation at Ser112 in human MV-4-11 cells assessed as phospho-BAD level after 4 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBcl2-associated agonist of cell death(Human)
Cylene Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50357618(CHEMBL1914471)
Affinity DataEC50:  760nMAssay Description:Inhibition of BAD phosphorylation at Ser112 in human MV-4-11 cells assessed as phospho-BAD level after 4 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Cylene Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50357587(CHEMBL1915438)
Affinity DataEC50:  4.80E+3nMAssay Description:Inhibition of FLT3 phosphorylation at Tyr591 in human MV-4-11 cells assessed as phospho-FLT3 level after 4 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Cylene Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50357591(CHEMBL1915442)
Affinity DataEC50: >1.00E+4nMAssay Description:Inhibition of FLT3 phosphorylation at Tyr591 in human MV-4-11 cells assessed as phospho-FLT3 level after 4 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Cylene Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50357594(CHEMBL1915445)
Affinity DataEC50:  1.50E+3nMAssay Description:Inhibition of FLT3 phosphorylation at Tyr591 in human MV-4-11 cells assessed as phospho-FLT3 level after 4 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Cylene Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50357616(CHEMBL1915650)
Affinity DataEC50:  8.90E+3nMAssay Description:Inhibition of FLT3 phosphorylation at Tyr591 in human MV-4-11 cells assessed as phospho-FLT3 level after 4 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Cylene Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50357597(CHEMBL1915448)
Affinity DataEC50:  6.00E+3nMAssay Description:Inhibition of FLT3 phosphorylation at Tyr591 in human MV-4-11 cells assessed as phospho-FLT3 level after 4 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Cylene Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50357598(CHEMBL1915449)
Affinity DataEC50: >1.00E+4nMAssay Description:Inhibition of FLT3 phosphorylation at Tyr591 in human MV-4-11 cells assessed as phospho-FLT3 level after 4 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Cylene Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50357602(CHEMBL1915636)
Affinity DataEC50:  5.30E+3nMAssay Description:Inhibition of FLT3 phosphorylation at Tyr591 in human MV-4-11 cells assessed as phospho-FLT3 level after 4 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Cylene Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50357607(CHEMBL1915641)
Affinity DataEC50: >1.00E+4nMAssay Description:Inhibition of FLT3 phosphorylation at Tyr591 in human MV-4-11 cells assessed as phospho-FLT3 level after 4 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Cylene Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50357610(CHEMBL1915644)
Affinity DataEC50:  2.60E+3nMAssay Description:Inhibition of FLT3 phosphorylation at Tyr591 in human MV-4-11 cells assessed as phospho-FLT3 level after 4 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Cylene Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50357611(CHEMBL1915645)
Affinity DataEC50:  4.40E+3nMAssay Description:Inhibition of FLT3 phosphorylation at Tyr591 in human MV-4-11 cells assessed as phospho-FLT3 level after 4 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase pim-2(Human)
Cylene Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50357594(CHEMBL1915445)
Affinity DataIC50: 1nMAssay Description:Inhibition of PIM2 by millipore assay in the presence of 15 uM [ATP]More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase pim-2(Human)
Cylene Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50357599(CHEMBL1915633)
Affinity DataIC50: 1nMAssay Description:Inhibition of human recombinant Pim2 using RSRHSSYPAGT as substrate by radiometric assay in the presence of 5 uM [ATP]More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase pim-2(Human)
Cylene Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50357602(CHEMBL1915636)
Affinity DataIC50: 1nMAssay Description:Inhibition of human recombinant Pim2 using RSRHSSYPAGT as substrate by radiometric assay in the presence of 5 uM [ATP]More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase pim-2(Human)
Cylene Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50357610(CHEMBL1915644)
Affinity DataIC50: 1nMAssay Description:Inhibition of human recombinant Pim2 using RSRHSSYPAGT as substrate by radiometric assay in the presence of 5 uM [ATP]More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase pim-1(Human)
Cylene Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50357587(CHEMBL1915438)
Affinity DataIC50: 1nMAssay Description:Inhibition of PIM1 using KKRNRTLTV as substrate by millipore assay in the presence of 90 uM [ATP]More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase pim-1(Human)
Cylene Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50357597(CHEMBL1915448)
Affinity DataIC50: 2nMAssay Description:Inhibition of human recombinant Pim1 using RSRHSSYPAGT as substrate by radiometric assay in the presence of 30 uM [ATP]More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase pim-1(Human)
Cylene Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50357598(CHEMBL1915449)
Affinity DataIC50: 2nMAssay Description:Inhibition of human recombinant Pim1 using RSRHSSYPAGT as substrate by radiometric assay in the presence of 30 uM [ATP]More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase pim-1(Human)
Cylene Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50357602(CHEMBL1915636)
Affinity DataIC50: 2nMAssay Description:Inhibition of human recombinant Pim1 using RSRHSSYPAGT as substrate by radiometric assay in the presence of 30 uM [ATP]More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase pim-2(Human)
Cylene Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50357594(CHEMBL1915445)
Affinity DataIC50: 2nMAssay Description:Inhibition of human recombinant Pim2 using RSRHSSYPAGT as substrate by radiometric assay in the presence of 5 uM [ATP]More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase pim-2(Human)
Cylene Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50357612(CHEMBL1915646)
Affinity DataIC50: 2nMAssay Description:Inhibition of human recombinant Pim2 using RSRHSSYPAGT as substrate by radiometric assay in the presence of 5 uM [ATP]More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase pim-2(Human)
Cylene Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50357613(CHEMBL1915647)
Affinity DataIC50: 2nMAssay Description:Inhibition of human recombinant Pim2 using RSRHSSYPAGT as substrate by radiometric assay in the presence of 5 uM [ATP]More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase pim-2(Human)
Cylene Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50357618(CHEMBL1914471)
Affinity DataIC50: 2nMAssay Description:Inhibition of human recombinant Pim2 using RSRHSSYPAGT as substrate by radiometric assay in the presence of 5 uM [ATP]More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase pim-1(Human)
Cylene Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50357594(CHEMBL1915445)
Affinity DataIC50: 2nMAssay Description:Inhibition of PIM1 using KKRNRTLTV as substrate by millipore assay in the presence of 90 uM [ATP]More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase pim-1(Human)
Cylene Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50357597(CHEMBL1915448)
Affinity DataIC50: 2nMAssay Description:Inhibition of PIM1 using KKRNRTLTV as substrate by millipore assay in the presence of 90 uM [ATP]More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase pim-2(Human)
Cylene Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50357591(CHEMBL1915442)
Affinity DataIC50: 3nMAssay Description:Inhibition of human recombinant Pim2 using RSRHSSYPAGT as substrate by radiometric assay in the presence of 5 uM [ATP]More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase pim-1(Human)
Cylene Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50357607(CHEMBL1915641)
Affinity DataIC50: 4nMAssay Description:Inhibition of human recombinant Pim1 using RSRHSSYPAGT as substrate by radiometric assay in the presence of 30 uM [ATP]More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase pim-2(Human)
Cylene Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50357616(CHEMBL1915650)
Affinity DataIC50: 4nMAssay Description:Inhibition of human recombinant Pim2 using RSRHSSYPAGT as substrate by radiometric assay in the presence of 5 uM [ATP]More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase pim-2(Human)
Cylene Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50357617(CHEMBL1915651)
Affinity DataIC50: 4nMAssay Description:Inhibition of human recombinant Pim2 using RSRHSSYPAGT as substrate by radiometric assay in the presence of 5 uM [ATP]More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase pim-1(Human)
Cylene Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50357587(CHEMBL1915438)
Affinity DataIC50: 5nMAssay Description:Inhibition of human recombinant Pim1 using RSRHSSYPAGT as substrate by radiometric assay in the presence of 30 uM [ATP]More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase pim-1(Human)
Cylene Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50357591(CHEMBL1915442)
Affinity DataIC50: 5nMAssay Description:Inhibition of human recombinant Pim1 using RSRHSSYPAGT as substrate by radiometric assay in the presence of 30 uM [ATP]More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase pim-1(Human)
Cylene Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50357594(CHEMBL1915445)
Affinity DataIC50: 5nMAssay Description:Inhibition of human recombinant Pim1 using RSRHSSYPAGT as substrate by radiometric assay in the presence of 30 uM [ATP]More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase pim-2(Human)
Cylene Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50357591(CHEMBL1915442)
Affinity DataIC50: 5nMAssay Description:Inhibition of PIM2 by millipore assay in the presence of 15 uM [ATP]More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase pim-2(Human)
Cylene Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50357610(CHEMBL1915644)
Affinity DataIC50: 5nMAssay Description:Inhibition of PIM2 by millipore assay in the presence of 15 uM [ATP]More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase pim-2(Human)
Cylene Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50357611(CHEMBL1915645)
Affinity DataIC50: 5nMAssay Description:Inhibition of human recombinant Pim2 using RSRHSSYPAGT as substrate by radiometric assay in the presence of 5 uM [ATP]More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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