Compile Data Set for Download or QSAR
Report error Found 34 Enz. Inhib. hit(s) with all data for entry = 50033796
TargetSolute carrier family 5 member 4(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM20878((2R,3S,4S,5R,6S)-2-(hydroxymethyl)-6-{2-[(4-methox...)
Affinity DataIC50: 4.80nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]AMG uptake after 45 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetSolute carrier family 5 member 4(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50351435(CHEMBL1819489)
Affinity DataIC50: 11nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]AMG uptake after 45 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetSolute carrier family 5 member 4(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM20875(CHEMBL245067 | JMC511145 Compound 1 | 1-(2,4-dihyd...)
Affinity DataIC50: 16nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]AMG uptake after 45 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetSolute carrier family 5 member 4(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50351439(CHEMBL1819492)
Affinity DataIC50: 19nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]AMG uptake after 45 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetSolute carrier family 5 member 4(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50351432(CHEMBL1819486)
Affinity DataIC50: 28nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]AMG uptake after 45 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetSolute carrier family 5 member 4(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50351436(CHEMBL1819490)
Affinity DataIC50: 29nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]AMG uptake after 45 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetSolute carrier family 5 member 4(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50351437(CHEMBL1819491)
Affinity DataIC50: 42nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]AMG uptake after 45 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetSolute carrier family 5 member 4(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50351431(CHEMBL1819485)
Affinity DataIC50: 59nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]AMG uptake after 45 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetSolute carrier family 5 member 4(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50351438(CHEMBL1817688)
Affinity DataIC50: 110nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]AMG uptake after 45 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetSolute carrier family 5 member 4(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50351433(CHEMBL1819487)
Affinity DataIC50: 120nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]AMG uptake after 45 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetSolute carrier family 5 member 4(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50351443(CHEMBL1819496)
Affinity DataIC50: 120nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]AMG uptake after 45 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetSolute carrier family 5 member 4(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50351434(CHEMBL1819488)
Affinity DataIC50: 150nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]AMG uptake after 45 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetSolute carrier family 5 member 4(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50351442(CHEMBL1819495)
Affinity DataIC50: 150nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]AMG uptake after 45 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM20875(CHEMBL245067 | JMC511145 Compound 1 | 1-(2,4-dihyd...)
Affinity DataIC50: 190nMAssay Description:Inhibition of human SGLT1 expressed in CHO cells assessed as [14C]AMG uptake after 45 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetSolute carrier family 5 member 4(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50351429(CHEMBL450044)
Affinity DataIC50: 260nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]AMG uptake after 45 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetSolute carrier family 5 member 4(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50351440(CHEMBL1819493)
Affinity DataIC50: 290nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]AMG uptake after 45 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetSolute carrier family 5 member 4(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50351441(CHEMBL1819494)
Affinity DataIC50: 630nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]AMG uptake after 45 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetSolute carrier family 5 member 4(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50351430(CHEMBL1819484)
Affinity DataIC50: 690nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]AMG uptake after 45 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM20878((2R,3S,4S,5R,6S)-2-(hydroxymethyl)-6-{2-[(4-methox...)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of human SGLT1 expressed in CHO cells assessed as [14C]AMG uptake after 45 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50351436(CHEMBL1819490)
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of human SGLT1 expressed in CHO cells assessed as [14C]AMG uptake after 45 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50351439(CHEMBL1819492)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of human SGLT1 expressed in CHO cells assessed as [14C]AMG uptake after 45 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50351432(CHEMBL1819486)
Affinity DataIC50: 4.80E+3nMAssay Description:Inhibition of human SGLT1 expressed in CHO cells assessed as [14C]AMG uptake after 45 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50351435(CHEMBL1819489)
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of human SGLT1 expressed in CHO cells assessed as [14C]AMG uptake after 45 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50351431(CHEMBL1819485)
Affinity DataIC50: 6.70E+3nMAssay Description:Inhibition of human SGLT1 expressed in CHO cells assessed as [14C]AMG uptake after 45 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50351433(CHEMBL1819487)
Affinity DataIC50: 7.80E+3nMAssay Description:Inhibition of human SGLT1 expressed in CHO cells assessed as [14C]AMG uptake after 45 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50351437(CHEMBL1819491)
Affinity DataIC50: 9.30E+3nMAssay Description:Inhibition of human SGLT1 expressed in CHO cells assessed as [14C]AMG uptake after 45 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50351430(CHEMBL1819484)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of human SGLT1 expressed in CHO cells assessed as [14C]AMG uptake after 45 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50351440(CHEMBL1819493)
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of human SGLT1 expressed in CHO cells assessed as [14C]AMG uptake after 45 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50351434(CHEMBL1819488)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human SGLT1 expressed in CHO cells assessed as [14C]AMG uptake after 45 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50351429(CHEMBL450044)
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of human SGLT1 expressed in CHO cells assessed as [14C]AMG uptake after 45 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50351442(CHEMBL1819495)
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of human SGLT1 expressed in CHO cells assessed as [14C]AMG uptake after 45 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50351441(CHEMBL1819494)
Affinity DataIC50: 3.80E+4nMAssay Description:Inhibition of human SGLT1 expressed in CHO cells assessed as [14C]AMG uptake after 45 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50351438(CHEMBL1817688)
Affinity DataIC50: 4.10E+4nMAssay Description:Inhibition of human SGLT1 expressed in CHO cells assessed as [14C]AMG uptake after 45 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50351443(CHEMBL1819496)
Affinity DataIC50: 5.70E+4nMAssay Description:Inhibition of human SGLT1 expressed in CHO cells assessed as [14C]AMG uptake after 45 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed