Compile Data Set for Download or QSAR
Report error Found 71 Enz. Inhib. hit(s) with all data for entry = 50041941
TargetPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50419064(CHEMBL1823874)
Affinity DataIC50: 15.8nMAssay Description:Inhibition of human HCN1 heterologously expressed in HEK-293 cells after 30 mins by VIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50419065(CHEMBL1823875)
Affinity DataIC50: 31.6nMAssay Description:Inhibition of human HCN1 heterologously expressed in HEK-293 cells after 30 mins by VIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50419053(ZD-7288 | CHEMBL2052019)
Affinity DataIC50: 31.6nMAssay Description:Inhibition of human HCN4 heterologously expressed in HEK-293 cells after 30 mins by VIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50419067(CHEMBL1823878)
Affinity DataIC50: 31.6nMAssay Description:Inhibition of human HCN1 heterologously expressed in HEK-293 cells after 30 mins by VIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50419068(CHEMBL1823879)
Affinity DataIC50: 50.1nMAssay Description:Inhibition of human HCN1 heterologously expressed in HEK-293 cells after 30 mins by VIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50419069(CHEMBL1823880)
Affinity DataIC50: 79.4nMAssay Description:Inhibition of human HCN1 heterologously expressed in HEK-293 cells after 30 mins by VIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50419080(CHEMBL1823677)
Affinity DataIC50: 126nMAssay Description:Inhibition of human HCN1 heterologously expressed in HEK-293 cells after 30 mins by VIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50419053(ZD-7288 | CHEMBL2052019)
Affinity DataIC50: 158nMAssay Description:Inhibition of human HCN1 heterologously expressed in HEK-293 cells after 30 mins by VIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50419067(CHEMBL1823878)
Affinity DataIC50: 158nMAssay Description:Inhibition of human HCN4 heterologously expressed in HEK-293 cells after 30 mins by VIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50419070(CHEMBL1823881)
Affinity DataIC50: 200nMAssay Description:Inhibition of human HCN1 heterologously expressed in HEK-293 cells after 30 mins by VIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50419066(CHEMBL1823876)
Affinity DataIC50: 251nMAssay Description:Inhibition of human HCN1 heterologously expressed in HEK-293 cells after 30 mins by VIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50419085(CHEMBL1823887)
Affinity DataIC50: 316nMAssay Description:Inhibition of human HCN1 heterologously expressed in HEK-293 cells after 30 mins by VIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50419068(CHEMBL1823879)
Affinity DataIC50: 316nMAssay Description:Inhibition of human HCN4 heterologously expressed in HEK-293 cells after 30 mins by VIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50419064(CHEMBL1823874)
Affinity DataIC50: 316nMAssay Description:Inhibition of human HCN4 heterologously expressed in HEK-293 cells after 30 mins by VIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50419055(CHEMBL1823666)
Affinity DataIC50: 398nMAssay Description:Inhibition of human HCN1 heterologously expressed in HEK-293 cells after 30 mins by VIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50419074(CHEMBL1823886)
Affinity DataIC50: 398nMAssay Description:Inhibition of human HCN1 heterologously expressed in HEK-293 cells after 30 mins by VIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50419083(CHEMBL1823882)
Affinity DataIC50: 398nMAssay Description:Inhibition of human HCN1 heterologously expressed in HEK-293 cells after 30 mins by VIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50419062(CHEMBL1435630)
Affinity DataIC50: 398nMAssay Description:Inhibition of human HCN1 heterologously expressed in HEK-293 cells after 30 mins by VIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50419060(CHEMBL1823674)
Affinity DataIC50: 631nMAssay Description:Inhibition of human HCN1 heterologously expressed in HEK-293 cells after 30 mins by VIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50419075(CHEMBL1823888)
Affinity DataIC50: 631nMAssay Description:Inhibition of human HCN1 heterologously expressed in HEK-293 cells after 30 mins by VIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50419078(CHEMBL1823667)
Affinity DataIC50: 631nMAssay Description:Inhibition of human HCN1 heterologously expressed in HEK-293 cells after 30 mins by VIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50419069(CHEMBL1823880)
Affinity DataIC50: 794nMAssay Description:Inhibition of human HCN4 heterologously expressed in HEK-293 cells after 30 mins by VIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50419065(CHEMBL1823875)
Affinity DataIC50: 794nMAssay Description:Inhibition of human HCN4 heterologously expressed in HEK-293 cells after 30 mins by VIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50419070(CHEMBL1823881)
Affinity DataIC50: 794nMAssay Description:Inhibition of human HCN4 heterologously expressed in HEK-293 cells after 30 mins by VIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50419080(CHEMBL1823677)
Affinity DataIC50: 1.26E+3nMAssay Description:Inhibition of human HCN4 heterologously expressed in HEK-293 cells after 30 mins by VIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50419054(CHEMBL1823665)
Affinity DataIC50: 1.26E+3nMAssay Description:Inhibition of human HCN1 heterologously expressed in HEK-293 cells after 30 mins by VIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50419066(CHEMBL1823876)
Affinity DataIC50: 1.58E+3nMAssay Description:Inhibition of human HCN4 heterologously expressed in HEK-293 cells after 30 mins by VIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50419084(CHEMBL1823885)
Affinity DataIC50: 1.58E+3nMAssay Description:Inhibition of human HCN1 heterologously expressed in HEK-293 cells after 30 mins by VIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50419078(CHEMBL1823667)
Affinity DataIC50: 2.51E+3nMAssay Description:Inhibition of human HCN4 heterologously expressed in HEK-293 cells after 30 mins by VIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50419076(CHEMBL1823889)
Affinity DataIC50: 2.51E+3nMAssay Description:Inhibition of human HCN1 heterologously expressed in HEK-293 cells after 30 mins by VIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50419083(CHEMBL1823882)
Affinity DataIC50: 3.16E+3nMAssay Description:Inhibition of human HCN3 heterologously expressed in HEK-293 cells after 30 mins by VIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50419060(CHEMBL1823674)
Affinity DataIC50: 3.16E+3nMAssay Description:Inhibition of human HCN4 heterologously expressed in HEK-293 cells after 30 mins by VIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50419083(CHEMBL1823882)
Affinity DataIC50: 3.98E+3nMAssay Description:Inhibition of human HCN4 heterologously expressed in HEK-293 cells after 30 mins by VIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50419085(CHEMBL1823887)
Affinity DataIC50: 3.98E+3nMAssay Description:Inhibition of human HCN4 heterologously expressed in HEK-293 cells after 30 mins by VIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50419055(CHEMBL1823666)
Affinity DataIC50: 5.01E+3nMAssay Description:Inhibition of human HCN4 heterologously expressed in HEK-293 cells after 30 mins by VIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50419062(CHEMBL1435630)
Affinity DataIC50: 5.01E+3nMAssay Description:Inhibition of human HCN4 heterologously expressed in HEK-293 cells after 30 mins by VIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50419074(CHEMBL1823886)
Affinity DataIC50: 5.01E+3nMAssay Description:Inhibition of human HCN4 heterologously expressed in HEK-293 cells after 30 mins by VIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50419083(CHEMBL1823882)
Affinity DataIC50: 5.01E+3nMAssay Description:Inhibition of human HCN2 heterologously expressed in HEK-293 cells after 30 mins by VIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50419075(CHEMBL1823888)
Affinity DataIC50: 5.01E+3nMAssay Description:Inhibition of human HCN4 heterologously expressed in HEK-293 cells after 30 mins by VIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50419084(CHEMBL1823885)
Affinity DataIC50: 6.31E+3nMAssay Description:Inhibition of human HCN4 heterologously expressed in HEK-293 cells after 30 mins by VIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50419087(CHEMBL1823676)
Affinity DataIC50: 1.58E+4nMAssay Description:Inhibition of human HCN1 heterologously expressed in HEK-293 cells after 30 mins by VIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50419071(CHEMBL1823883)
Affinity DataIC50: 1.58E+4nMAssay Description:Inhibition of human HCN1 heterologously expressed in HEK-293 cells after 30 mins by VIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50419086(CHEMBL1823671)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human HCN1 heterologously expressed in HEK-293 cells after 30 mins by VIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50419054(CHEMBL1823665)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human HCN4 heterologously expressed in HEK-293 cells after 30 mins by VIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50419076(CHEMBL1823889)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human HCN4 heterologously expressed in HEK-293 cells after 30 mins by VIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50419079(CHEMBL1823673)
Affinity DataIC50: 2.51E+4nMAssay Description:Inhibition of human HCN1 heterologously expressed in HEK-293 cells after 30 mins by VIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50419056(CHEMBL1823668)
Affinity DataIC50: 2.51E+4nMAssay Description:Inhibition of human HCN1 heterologously expressed in HEK-293 cells after 30 mins by VIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50419081(CHEMBL1823679)
Affinity DataIC50: 3.16E+4nMAssay Description:Inhibition of human HCN4 heterologously expressed in HEK-293 cells after 30 mins by VIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50419071(CHEMBL1823883)
Affinity DataIC50: 3.98E+4nMAssay Description:Inhibition of human HCN4 heterologously expressed in HEK-293 cells after 30 mins by VIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50419087(CHEMBL1823676)
Affinity DataIC50: 3.98E+4nMAssay Description:Inhibition of human HCN4 heterologously expressed in HEK-293 cells after 30 mins by VIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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