Compile Data Set for Download or QSAR
Report error Found 26 Enz. Inhib. hit(s) with all data for entry = 50034140
LigandPNGBDBM50419436(CHEMBL1915747 | US9138494, JNJ-41510417)
Affinity DataIC50: 0.501nMAssay Description:Inhibition of rat recombinant PDE10A expressed in baculovirus infected insect Sf9 cells using [3H]cAMP as substrate after 60 mins by scintillation co...More data for this Ligand-Target Pair
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PubMed
LigandPNGBDBM31592(PF-2545920 | substituted pyrazole, 9 | US9138494, ...)
Affinity DataIC50: 0.501nMAssay Description:Inhibition of rat recombinant PDE10A expressed in baculovirus infected insect Sf9 cells using [3H]cAMP as substrate after 60 mins by scintillation co...More data for this Ligand-Target Pair
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PubMed
LigandPNGBDBM50357701(CHEMBL1915725 | US9138494, Janssen B-3)
Affinity DataIC50: 1.58nMAssay Description:Inhibition of rat recombinant PDE10A expressed in baculovirus infected insect Sf9 cells using [3H]cAMP as substrate after 60 mins by scintillation co...More data for this Ligand-Target Pair
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PubMed
LigandPNGBDBM50419439(CHEMBL1915727)
Affinity DataIC50: 2.51nMAssay Description:Inhibition of rat recombinant PDE10A expressed in baculovirus infected insect Sf9 cells using [3H]cAMP as substrate after 60 mins by scintillation co...More data for this Ligand-Target Pair
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PubMed
LigandPNGBDBM50357702(CHEMBL1915726)
Affinity DataIC50: 3.16nMAssay Description:Inhibition of rat recombinant PDE10A expressed in baculovirus infected insect Sf9 cells using [3H]cAMP as substrate after 60 mins by scintillation co...More data for this Ligand-Target Pair
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PubMed
LigandPNGBDBM50419437(CHEMBL1915742)
Affinity DataIC50: 3.16nMAssay Description:Inhibition of rat recombinant PDE10A expressed in baculovirus infected insect Sf9 cells using [3H]cAMP as substrate after 60 mins by scintillation co...More data for this Ligand-Target Pair
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PubMed
LigandPNGBDBM50419442(CHEMBL1915746)
Affinity DataIC50: 3.98nMAssay Description:Inhibition of rat recombinant PDE10A expressed in baculovirus infected insect Sf9 cells using [3H]cAMP as substrate after 60 mins by scintillation co...More data for this Ligand-Target Pair
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PubMed
LigandPNGBDBM50419428(CHEMBL1915736)
Affinity DataIC50: 3.98nMAssay Description:Inhibition of rat recombinant PDE10A expressed in baculovirus infected insect Sf9 cells using [3H]cAMP as substrate after 60 mins by scintillation co...More data for this Ligand-Target Pair
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PubMed
LigandPNGBDBM50419423(CHEMBL1915729)
Affinity DataIC50: 5.01nMAssay Description:Inhibition of rat recombinant PDE10A expressed in baculovirus infected insect Sf9 cells using [3H]cAMP as substrate after 60 mins by scintillation co...More data for this Ligand-Target Pair
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PubMed
LigandPNGBDBM50419426(CHEMBL1915733)
Affinity DataIC50: 5.01nMAssay Description:Inhibition of rat recombinant PDE10A expressed in baculovirus infected insect Sf9 cells using [3H]cAMP as substrate after 60 mins by scintillation co...More data for this Ligand-Target Pair
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PubMed
LigandPNGBDBM50419424(CHEMBL1915730)
Affinity DataIC50: 10nMAssay Description:Inhibition of rat recombinant PDE10A expressed in baculovirus infected insect Sf9 cells using [3H]cAMP as substrate after 60 mins by scintillation co...More data for this Ligand-Target Pair
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PubMed
LigandPNGBDBM50419430(CHEMBL1915738)
Affinity DataIC50: 10nMAssay Description:Inhibition of rat recombinant PDE10A expressed in baculovirus infected insect Sf9 cells using [3H]cAMP as substrate after 60 mins by scintillation co...More data for this Ligand-Target Pair
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PubMed
LigandPNGBDBM50419440(CHEMBL1915734)
Affinity DataIC50: 12.6nMAssay Description:Inhibition of rat recombinant PDE10A expressed in baculovirus infected insect Sf9 cells using [3H]cAMP as substrate after 60 mins by scintillation co...More data for this Ligand-Target Pair
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PubMed
LigandPNGBDBM50419429(CHEMBL1915737)
Affinity DataIC50: 15.8nMAssay Description:Inhibition of rat recombinant PDE10A expressed in baculovirus infected insect Sf9 cells using [3H]cAMP as substrate after 60 mins by scintillation co...More data for this Ligand-Target Pair
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PubMed
LigandPNGBDBM50419427(CHEMBL1915735)
Affinity DataIC50: 15.8nMAssay Description:Inhibition of rat recombinant PDE10A expressed in baculovirus infected insect Sf9 cells using [3H]cAMP as substrate after 60 mins by scintillation co...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50419433(CHEMBL1915743)
Affinity DataIC50: 19.9nMAssay Description:Inhibition of rat recombinant PDE10A expressed in baculovirus infected insect Sf9 cells using [3H]cAMP as substrate after 60 mins by scintillation co...More data for this Ligand-Target Pair
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PubMed
LigandPNGBDBM50419422(CHEMBL1915728)
Affinity DataIC50: 19.9nMAssay Description:Inhibition of rat recombinant PDE10A expressed in baculovirus infected insect Sf9 cells using [3H]cAMP as substrate after 60 mins by scintillation co...More data for this Ligand-Target Pair
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PubMed
LigandPNGBDBM50419432(CHEMBL1915741)
Affinity DataIC50: 31.6nMAssay Description:Inhibition of rat recombinant PDE10A expressed in baculovirus infected insect Sf9 cells using [3H]cAMP as substrate after 60 mins by scintillation co...More data for this Ligand-Target Pair
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PubMed
LigandPNGBDBM50419434(CHEMBL1915744)
Affinity DataIC50: 31.6nMAssay Description:Inhibition of rat recombinant PDE10A expressed in baculovirus infected insect Sf9 cells using [3H]cAMP as substrate after 60 mins by scintillation co...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50419435(CHEMBL1915745)
Affinity DataIC50: 31.6nMAssay Description:Inhibition of rat recombinant PDE10A expressed in baculovirus infected insect Sf9 cells using [3H]cAMP as substrate after 60 mins by scintillation co...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50419438(CHEMBL1915732)
Affinity DataIC50: 31.6nMAssay Description:Inhibition of rat recombinant PDE10A expressed in baculovirus infected insect Sf9 cells using [3H]cAMP as substrate after 60 mins by scintillation co...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50419431(CHEMBL1915739)
Affinity DataIC50: 79.4nMAssay Description:Inhibition of rat recombinant PDE10A expressed in baculovirus infected insect Sf9 cells using [3H]cAMP as substrate after 60 mins by scintillation co...More data for this Ligand-Target Pair
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PubMed
LigandPNGBDBM50419425(CHEMBL1915731)
Affinity DataIC50: 100nMAssay Description:Inhibition of rat recombinant PDE10A expressed in baculovirus infected insect Sf9 cells using [3H]cAMP as substrate after 60 mins by scintillation co...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50419441(CHEMBL1915740)
Affinity DataIC50: 100nMAssay Description:Inhibition of rat recombinant PDE10A expressed in baculovirus infected insect Sf9 cells using [3H]cAMP as substrate after 60 mins by scintillation co...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50357702(CHEMBL1915726)
Affinity DataIC50: 870nMAssay Description:Inhibition of human DATMore data for this Ligand-Target Pair
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PubMed
TargetSodium-dependent dopamine transporter(Human)
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50357701(CHEMBL1915725 | US9138494, Janssen B-3)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of human DATMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed