Compile Data Set for Download or QSAR
Report error Found 32 Enz. Inhib. hit(s) with all data for entry = 50033732
TargetSerine/threonine-protein kinase pim-1(Human)
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM50350424(CHEMBL454440)
Affinity DataIC50: 300nMAssay Description:Inhibition of recombinant PIM1 assessed as 33Pi incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase pim-1(Human)
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM50350423(CHEMBL466154)
Affinity DataIC50: 300nMAssay Description:Inhibition of recombinant PIM1 assessed as 33Pi incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM50350424(CHEMBL454440)
Affinity DataIC50: 500nMAssay Description:Inhibition of recombinant Aurora-b assessed as 33Pi incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM50350424(CHEMBL454440)
Affinity DataIC50: 800nMAssay Description:Inhibition of recombinant VEGF-R2 assessed as 33Pi incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM50350424(CHEMBL454440)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of recombinant ALK assessed as 33Pi incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM50350423(CHEMBL466154)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of recombinant Aurora-b assessed as 33Pi incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM50350424(CHEMBL454440)
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibition of wild type MET assessed as 33Pi incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetTyrosine-protein kinase receptor UFO(Human)
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM50350424(CHEMBL454440)
Affinity DataIC50: 6.60E+3nMAssay Description:Inhibition of recombinant AXL assessed as 33Pi incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM50350424(CHEMBL454440)
Affinity DataIC50: 8.60E+3nMAssay Description:Inhibition of recombinant IGF1-R assessed as 33Pi incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK1(Human)
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM50350424(CHEMBL454440)
Affinity DataIC50: 8.80E+3nMAssay Description:Inhibition of recombinant PLK1 assessed as 33Pi incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM50350423(CHEMBL466154)
Affinity DataIC50: 1.17E+4nMAssay Description:Inhibition of recombinant VEGF-R2 assessed as 33Pi incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM50350424(CHEMBL454440)
Affinity DataIC50: 1.29E+4nMAssay Description:Inhibition of recombinant SRC assessed as 33Pi incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetFocal adhesion kinase 1(Human)
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM50350424(CHEMBL454440)
Affinity DataIC50: 1.52E+4nMAssay Description:Inhibition of recombinant FAK assessed as 33Pi incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetNUAK family SNF1-like kinase 1(Human)
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM50350424(CHEMBL454440)
Affinity DataIC50: 1.56E+4nMAssay Description:Inhibition of recombinant ARK5 assessed as 33Pi incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetNUAK family SNF1-like kinase 1(Human)
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM50350423(CHEMBL466154)
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of recombinant ARK5 assessed as 33Pi incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM50350423(CHEMBL466154)
Affinity DataIC50: 3.33E+4nMAssay Description:Inhibition of recombinant IGF1-R assessed as 33Pi incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM50350423(CHEMBL466154)
Affinity DataIC50: 3.50E+4nMAssay Description:Inhibition of recombinant SRC assessed as 33Pi incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM50350423(CHEMBL466154)
Affinity DataIC50: 4.13E+4nMAssay Description:Inhibition of recombinant ALK assessed as 33Pi incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase N1(Human)
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM50350424(CHEMBL454440)
Affinity DataIC50: 4.53E+4nMAssay Description:Inhibition of recombinant PRK1 assessed as 33Pi incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase N1(Human)
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM50350423(CHEMBL466154)
Affinity DataIC50: 5.49E+4nMAssay Description:Inhibition of recombinant PRK1 assessed as 33Pi incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Nek6(Human)
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM50350424(CHEMBL454440)
Affinity DataIC50: 6.78E+4nMAssay Description:Inhibition of recombinant NEK6 assessed as 33Pi incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK1(Human)
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM50350423(CHEMBL466154)
Affinity DataIC50: 7.57E+4nMAssay Description:Inhibition of recombinant PLK1 assessed as 33Pi incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Nek2(Human)
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM50350424(CHEMBL454440)
Affinity DataIC50: 8.39E+4nMAssay Description:Inhibition of recombinant NEK2 assessed as 33Pi incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM50350423(CHEMBL466154)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant AKT1 assessed as 33Pi incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetTyrosine-protein kinase receptor UFO(Human)
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM50350423(CHEMBL466154)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant AXL assessed as 33Pi incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetFocal adhesion kinase 1(Human)
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM50350423(CHEMBL466154)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant FAK assessed as 33Pi incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM50350424(CHEMBL454440)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant AKT1 assessed as 33Pi incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Nek6(Human)
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM50350423(CHEMBL466154)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant NEK6 assessed as 33Pi incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Nek2(Human)
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM50350423(CHEMBL466154)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant NEK2 assessed as 33Pi incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM50350423(CHEMBL466154)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of wild type MET assessed as 33Pi incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM50350424(CHEMBL454440)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of wild type MEK1 assessed as 33Pi incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM50350423(CHEMBL466154)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of wild type MEK1 assessed as 33Pi incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed