Compile Data Set for Download or QSAR
Report error Found 63 Enz. Inhib. hit(s) with all data for entry = 50033727
TargetSmoothened homolog(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50349262(CHEMBL1813106 | CHEMBL1807225)
Affinity DataIC50: 4nMAssay Description:Displacement of BODIPY-cyclopamine from human Smo expressed in HEK293 cells in presence of 2% fetal calf serumMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSmoothened homolog(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50349262(CHEMBL1813106 | CHEMBL1807225)
Affinity DataIC50: 5nMAssay Description:Antagonist activity at smoothened expressed in mouse Shh Light2 cells assessed as inhibition of purmorphamine- induced Gli-dependent luciferase gene ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSmoothened homolog(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50350335(CHEMBL1813107)
Affinity DataIC50: 5nMAssay Description:Antagonist activity at smoothened expressed in mouse Shh Light2 cells assessed as inhibition of purmorphamine- induced Gli-dependent luciferase gene ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSmoothened homolog(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50350339(CHEMBL1813111)
Affinity DataIC50: 6nMAssay Description:Antagonist activity at smoothened expressed in mouse Shh Light2 cells assessed as inhibition of purmorphamine- induced Gli-dependent luciferase gene ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSmoothened homolog(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50350339(CHEMBL1813111)
Affinity DataIC50: 7nMAssay Description:Displacement of BODIPY-cyclopamine from human Smo expressed in HEK293 cells in presence of 2% fetal calf serumMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSmoothened homolog(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50350338(CHEMBL1813110)
Affinity DataIC50: 8nMAssay Description:Antagonist activity at smoothened expressed in mouse Shh Light2 cells assessed as inhibition of purmorphamine- induced Gli-dependent luciferase gene ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSmoothened homolog(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50350339(CHEMBL1813111)
Affinity DataIC50: 9nMAssay Description:Displacement of BODIPY-cyclopamine from human Smo expressed in HEK293 cells in presence of 20% normal human serumMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSmoothened homolog(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50349259(CHEMBL1813105 | CHEMBL1807222)
Affinity DataIC50: 12nMAssay Description:Displacement of BODIPY-cyclopamine from human Smo expressed in HEK293 cells in presence of 20% normal human serumMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSmoothened homolog(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50349259(CHEMBL1813105 | CHEMBL1807222)
Affinity DataIC50: 12nMAssay Description:Displacement of BODIPY-cyclopamine from human Smo expressed in HEK293 cells in presence of 2% fetal calf serumMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSmoothened homolog(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50350342(CHEMBL1813114)
Affinity DataIC50: 13nMAssay Description:Displacement of BODIPY-cyclopamine from human Smo expressed in HEK293 cells in presence of 2% fetal calf serumMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSmoothened homolog(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50349262(CHEMBL1813106 | CHEMBL1807225)
Affinity DataIC50: 15nMAssay Description:Displacement of BODIPY-cyclopamine from human Smo expressed in HEK293 cells in presence of 20% normal human serumMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSmoothened homolog(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50349268(CHEMBL1813109 | CHEMBL1807231)
Affinity DataIC50: 15nMAssay Description:Displacement of BODIPY-cyclopamine from human Smo expressed in HEK293 cells in presence of 2% fetal calf serumMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSmoothened homolog(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50350335(CHEMBL1813107)
Affinity DataIC50: 16nMAssay Description:Displacement of BODIPY-cyclopamine from human Smo expressed in HEK293 cells in presence of 2% fetal calf serumMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSmoothened homolog(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50350342(CHEMBL1813114)
Affinity DataIC50: 17nMAssay Description:Antagonist activity at smoothened expressed in mouse Shh Light2 cells assessed as inhibition of purmorphamine- induced Gli-dependent luciferase gene ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSmoothened homolog(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50349268(CHEMBL1813109 | CHEMBL1807231)
Affinity DataIC50: 18nMAssay Description:Displacement of BODIPY-cyclopamine from human Smo expressed in HEK293 cells in presence of 20% normal human serumMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSmoothened homolog(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50350338(CHEMBL1813110)
Affinity DataIC50: 18nMAssay Description:Displacement of BODIPY-cyclopamine from human Smo expressed in HEK293 cells in presence of 2% fetal calf serumMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSmoothened homolog(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50349268(CHEMBL1813109 | CHEMBL1807231)
Affinity DataIC50: 18nMAssay Description:Antagonist activity at smoothened expressed in mouse Shh Light2 cells assessed as inhibition of purmorphamine- induced Gli-dependent luciferase gene ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSmoothened homolog(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50350341(CHEMBL1813113)
Affinity DataIC50: 19nMAssay Description:Displacement of BODIPY-cyclopamine from human Smo expressed in HEK293 cells in presence of 2% fetal calf serumMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSmoothened homolog(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50349282(CHEMBL1808284 | CHEMBL1813096)
Affinity DataIC50: 21nMAssay Description:Displacement of BODIPY-cyclopamine from human Smo expressed in HEK293 cells in presence of 2% fetal calf serumMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSmoothened homolog(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50349266(CHEMBL1807229 | CHEMBL1813108)
Affinity DataIC50: 21nMAssay Description:Displacement of BODIPY-cyclopamine from human Smo expressed in HEK293 cells in presence of 2% fetal calf serumMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSmoothened homolog(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50350335(CHEMBL1813107)
Affinity DataIC50: 22nMAssay Description:Displacement of BODIPY-cyclopamine from human Smo expressed in HEK293 cells in presence of 20% normal human serumMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSmoothened homolog(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50350342(CHEMBL1813114)
Affinity DataIC50: 22nMAssay Description:Displacement of BODIPY-cyclopamine from human Smo expressed in HEK293 cells in presence of 20% normal human serumMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSmoothened homolog(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50350341(CHEMBL1813113)
Affinity DataIC50: 23nMAssay Description:Antagonist activity at smoothened expressed in mouse Shh Light2 cells assessed as inhibition of purmorphamine- induced Gli-dependent luciferase gene ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSmoothened homolog(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50349259(CHEMBL1813105 | CHEMBL1807222)
Affinity DataIC50: 28nMAssay Description:Antagonist activity at smoothened expressed in mouse Shh Light2 cells assessed as inhibition of purmorphamine- induced Gli-dependent luciferase gene ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSmoothened homolog(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50350338(CHEMBL1813110)
Affinity DataIC50: 32nMAssay Description:Displacement of BODIPY-cyclopamine from human Smo expressed in HEK293 cells in presence of 20% normal human serumMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSmoothened homolog(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50349297(CHEMBL1813104 | CHEMBL1808456)
Affinity DataIC50: 41nMAssay Description:Antagonist activity at smoothened expressed in mouse Shh Light2 cells assessed as inhibition of purmorphamine- induced Gli-dependent luciferase gene ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSmoothened homolog(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50349266(CHEMBL1807229 | CHEMBL1813108)
Affinity DataIC50: 42nMAssay Description:Displacement of BODIPY-cyclopamine from human Smo expressed in HEK293 cells in presence of 20% normal human serumMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSmoothened homolog(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50349282(CHEMBL1808284 | CHEMBL1813096)
Affinity DataIC50: 42nMAssay Description:Antagonist activity at smoothened expressed in mouse Shh Light2 cells assessed as inhibition of purmorphamine- induced Gli-dependent luciferase gene ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSmoothened homolog(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50349297(CHEMBL1813104 | CHEMBL1808456)
Affinity DataIC50: 42nMAssay Description:Displacement of BODIPY-cyclopamine from human Smo expressed in HEK293 cells in presence of 2% fetal calf serumMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSmoothened homolog(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50349282(CHEMBL1808284 | CHEMBL1813096)
Affinity DataIC50: 48nMAssay Description:Displacement of BODIPY-cyclopamine from human Smo expressed in HEK293 cells in presence of 2% fetal calf serumMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSmoothened homolog(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50349282(CHEMBL1808284 | CHEMBL1813096)
Affinity DataIC50: 48nMAssay Description:Displacement of BODIPY-cyclopamine from human Smo expressed in HEK293 cells in presence of 2% fetal calf serumMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSmoothened homolog(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50350341(CHEMBL1813113)
Affinity DataIC50: 60nMAssay Description:Displacement of BODIPY-cyclopamine from human Smo expressed in HEK293 cells in presence of 20% normal human serumMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSmoothened homolog(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50349297(CHEMBL1813104 | CHEMBL1808456)
Affinity DataIC50: 68nMAssay Description:Displacement of BODIPY-cyclopamine from human Smo expressed in HEK293 cells in presence of 20% normal human serumMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSmoothened homolog(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50349282(CHEMBL1808284 | CHEMBL1813096)
Affinity DataIC50: 70nMAssay Description:Displacement of BODIPY-cyclopamine from human Smo expressed in HEK293 cells in presence of 20% normal human serumMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSmoothened homolog(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50350331(CHEMBL1813103)
Affinity DataIC50: 77nMAssay Description:Displacement of BODIPY-cyclopamine from human Smo expressed in HEK293 cells in presence of 2% fetal calf serumMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSmoothened homolog(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50349266(CHEMBL1807229 | CHEMBL1813108)
Affinity DataIC50: 89nMAssay Description:Antagonist activity at smoothened expressed in mouse Shh Light2 cells assessed as inhibition of purmorphamine- induced Gli-dependent luciferase gene ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSmoothened homolog(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50349282(CHEMBL1808284 | CHEMBL1813096)
Affinity DataIC50: 95nMAssay Description:Displacement of BODIPY-cyclopamine from human Smo expressed in HEK293 cells in presence of 2% fetal calf serumMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSmoothened homolog(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50349298(CHEMBL1808457 | CHEMBL1813102)
Affinity DataIC50: 100nMAssay Description:Displacement of BODIPY-cyclopamine from human Smo expressed in HEK293 cells in presence of 2% fetal calf serumMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSmoothened homolog(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50349282(CHEMBL1808284 | CHEMBL1813096)
Affinity DataIC50: 100nMAssay Description:Antagonist activity at smoothened expressed in mouse Shh Light2 cells assessed as inhibition of purmorphamine- induced Gli-dependent luciferase gene ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSmoothened homolog(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50349282(CHEMBL1808284 | CHEMBL1813096)
Affinity DataIC50: 100nMAssay Description:Antagonist activity at smoothened expressed in mouse Shh Light2 cells assessed as inhibition of purmorphamine- induced Gli-dependent luciferase gene ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSmoothened homolog(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50350331(CHEMBL1813103)
Affinity DataIC50: 120nMAssay Description:Antagonist activity at smoothened expressed in mouse Shh Light2 cells assessed as inhibition of purmorphamine- induced Gli-dependent luciferase gene ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSmoothened homolog(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50350331(CHEMBL1813103)
Affinity DataIC50: 120nMAssay Description:Displacement of BODIPY-cyclopamine from human Smo expressed in HEK293 cells in presence of 20% normal human serumMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSmoothened homolog(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50349298(CHEMBL1808457 | CHEMBL1813102)
Affinity DataIC50: 120nMAssay Description:Antagonist activity at smoothened expressed in mouse Shh Light2 cells assessed as inhibition of purmorphamine- induced Gli-dependent luciferase gene ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSmoothened homolog(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50349294(CHEMBL1813101 | CHEMBL1808453)
Affinity DataIC50: 140nMAssay Description:Antagonist activity at smoothened expressed in mouse Shh Light2 cells assessed as inhibition of purmorphamine- induced Gli-dependent luciferase gene ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSmoothened homolog(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50349282(CHEMBL1808284 | CHEMBL1813096)
Affinity DataIC50: 140nMAssay Description:Antagonist activity at smoothened expressed in mouse Shh Light2 cells assessed as inhibition of purmorphamine- induced Gli-dependent luciferase gene ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSmoothened homolog(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50349294(CHEMBL1813101 | CHEMBL1808453)
Affinity DataIC50: 180nMAssay Description:Displacement of BODIPY-cyclopamine from human Smo expressed in HEK293 cells in presence of 2% fetal calf serumMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSmoothened homolog(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50349277(CHEMBL1813099 | CHEMBL1813097 | CHEMBL1808279)
Affinity DataIC50: 230nMAssay Description:Displacement of BODIPY-cyclopamine from human Smo expressed in HEK293 cells in presence of 2% fetal calf serumMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSmoothened homolog(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50349277(CHEMBL1813099 | CHEMBL1813097 | CHEMBL1808279)
Affinity DataIC50: 270nMAssay Description:Antagonist activity at smoothened expressed in mouse Shh Light2 cells assessed as inhibition of purmorphamine- induced Gli-dependent luciferase gene ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSmoothened homolog(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50349277(CHEMBL1813099 | CHEMBL1813097 | CHEMBL1808279)
Affinity DataIC50: 430nMAssay Description:Antagonist activity at smoothened expressed in mouse Shh Light2 cells assessed as inhibition of purmorphamine- induced Gli-dependent luciferase gene ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSmoothened homolog(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50349298(CHEMBL1808457 | CHEMBL1813102)
Affinity DataIC50: 450nMAssay Description:Displacement of BODIPY-cyclopamine from human Smo expressed in HEK293 cells in presence of 20% normal human serumMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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