Compile Data Set for Download or QSAR
Report error Found 22 Enz. Inhib. hit(s) with all data for entry = 50033383
TargetALK tyrosine kinase receptor(Human)
Pharmadesign

Curated by ChEMBL
LigandPNGBDBM50344203(5-Amino-3-[[3-(3-aminophenyl)-5-methyl-1H-pyrrol-2...)
Affinity DataIC50: 51nMAssay Description:Inhibition of ALK using FL-Peptide 13, 5-FAM-KKSRGDYMTMQIG-CONH2 substrate after 60 mins by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Pharmadesign

Curated by ChEMBL
LigandPNGBDBM50344205(3-[[3-(3-Aminophenyl)-5-methyl-1H-pyrrol-2-yl]meth...)
Affinity DataIC50: 62nMAssay Description:Inhibition of ALK using FL-Peptide 13, 5-FAM-KKSRGDYMTMQIG-CONH2 substrate after 60 mins by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Pharmadesign

Curated by ChEMBL
LigandPNGBDBM50344202(5-Amino-3-[[3-(4-aminophenyl)-5-methyl-1H-pyrrol-2...)
Affinity DataIC50: 68nMAssay Description:Inhibition of ALK using FL-Peptide 13, 5-FAM-KKSRGDYMTMQIG-CONH2 substrate after 60 mins by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Pharmadesign

Curated by ChEMBL
LigandPNGBDBM50344201(3-[[3-[3-[(2-Aminoethyl)amino]phenyl]]-5-methyl-1H...)
Affinity DataIC50: 89nMAssay Description:Inhibition of ALK using FL-Peptide 13, 5-FAM-KKSRGDYMTMQIG-CONH2 substrate after 60 mins by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Pharmadesign

Curated by ChEMBL
LigandPNGBDBM50344200(3-[[3-[4-[(2-Aminoethyl)amino]phenyl]]-5-methyl-1H...)
Affinity DataIC50: 149nMAssay Description:Inhibition of ALK using FL-Peptide 13, 5-FAM-KKSRGDYMTMQIG-CONH2 substrate after 60 mins by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Pharmadesign

Curated by ChEMBL
LigandPNGBDBM50344204(3-[[3-(4-Aminophenyl)-5-methyl-1H-pyrrol-2-yl]meth...)
Affinity DataIC50: 368nMAssay Description:Inhibition of ALK using FL-Peptide 13, 5-FAM-KKSRGDYMTMQIG-CONH2 substrate after 60 mins by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Pharmadesign

Curated by ChEMBL
LigandPNGBDBM50344198(3-[[4-[4-[(2-Aminoethyl)amino]phenyl]]-3,5-dimethy...)
Affinity DataIC50: 415nMAssay Description:Inhibition of ALK using FL-Peptide 13, 5-FAM-KKSRGDYMTMQIG-CONH2 substrate after 60 mins by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Pharmadesign

Curated by ChEMBL
LigandPNGBDBM50344199(3-[[4-[3-[(2-Aminoethyl)amino]phenyl]]-3,5-dimethy...)
Affinity DataIC50: 605nMAssay Description:Inhibition of ALK using FL-Peptide 13, 5-FAM-KKSRGDYMTMQIG-CONH2 substrate after 60 mins by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Pharmadesign

Curated by ChEMBL
LigandPNGBDBM50307127((Z)-N,N-dimethyl-2-oxo-3-((4,5,6,7-tetrahydro-1H-i...)
Affinity DataIC50: 850nMAssay Description:Inhibition of ALK using FL-Peptide 13, 5-FAM-KKSRGDYMTMQIG-CONH2 substrate after 60 mins by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Pharmadesign

Curated by ChEMBL
LigandPNGBDBM50344216((Z)-5-((5-fluoro-2-oxoindolin-3-ylidene)methyl)-2,...)
Affinity DataIC50: 910nMAssay Description:Inhibition of ALK using FL-Peptide 13, 5-FAM-KKSRGDYMTMQIG-CONH2 substrate after 60 mins by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Pharmadesign

Curated by ChEMBL
LigandPNGBDBM50344215(3-((2-ethyl-4-methyl-1H-imidazol-5-yl)methylene)in...)
Affinity DataIC50: 1.38E+3nMAssay Description:Inhibition of ALK using FL-Peptide 13, 5-FAM-KKSRGDYMTMQIG-CONH2 substrate after 60 mins by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Pharmadesign

Curated by ChEMBL
LigandPNGBDBM50344214(3-((3-phenyl-1H-pyrazol-4-yl)methylene)indolin-2-o...)
Affinity DataIC50: 1.73E+3nMAssay Description:Inhibition of ALK using FL-Peptide 13, 5-FAM-KKSRGDYMTMQIG-CONH2 substrate after 60 mins by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Pharmadesign

Curated by ChEMBL
LigandPNGBDBM4810(cid_5329098 | CHEMBL276711 | SU5146 | (3Z)-3-[(3,5...)
Affinity DataIC50: 1.81E+3nMAssay Description:Inhibition of ALK using FL-Peptide 13, 5-FAM-KKSRGDYMTMQIG-CONH2 substrate after 60 mins by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Pharmadesign

Curated by ChEMBL
LigandPNGBDBM50344213((E)-4-chloro-2-((2-(4-hydroxy-3-methoxyphenyl)-7-m...)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of ALK using FL-Peptide 13, 5-FAM-KKSRGDYMTMQIG-CONH2 substrate after 60 mins by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Pharmadesign

Curated by ChEMBL
LigandPNGBDBM50227519(CHEMBL405130 | CHEMBL555201 | 4-(6,7-dimethoxyquin...)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of ALK using FL-Peptide 13, 5-FAM-KKSRGDYMTMQIG-CONH2 substrate after 60 mins by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Pharmadesign

Curated by ChEMBL
LigandPNGBDBM50344212(4-(6-bromoquinazolin-4-ylamino)phenol | CHEMBL1778...)
Affinity DataIC50: 2.85E+3nMAssay Description:Inhibition of ALK using FL-Peptide 13, 5-FAM-KKSRGDYMTMQIG-CONH2 substrate after 60 mins by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Pharmadesign

Curated by ChEMBL
LigandPNGBDBM50344211(ethyl 4-(4-(4-chlorophenylamino)pteridin-2-ylamino...)
Affinity DataIC50: 3.47E+3nMAssay Description:Inhibition of ALK using FL-Peptide 13, 5-FAM-KKSRGDYMTMQIG-CONH2 substrate after 60 mins by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Pharmadesign

Curated by ChEMBL
LigandPNGBDBM50344210(5-(2-oxoindolin-3-ylidene)-2-(p-tolylamino)thiazol...)
Affinity DataIC50: 3.75E+3nMAssay Description:Inhibition of ALK using FL-Peptide 13, 5-FAM-KKSRGDYMTMQIG-CONH2 substrate after 60 mins by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Pharmadesign

Curated by ChEMBL
LigandPNGBDBM67668(cid_6097961 | CHEMBL1487936 | (6E)-6-[4-[(4-hydrox...)
Affinity DataIC50: 4.24E+3nMAssay Description:Inhibition of ALK using FL-Peptide 13, 5-FAM-KKSRGDYMTMQIG-CONH2 substrate after 60 mins by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Pharmadesign

Curated by ChEMBL
LigandPNGBDBM50344208(2-(4-(4-chlorophenylamino)quinazolin-2-yl)phenol |...)
Affinity DataIC50: 6.46E+3nMAssay Description:Inhibition of ALK using FL-Peptide 13, 5-FAM-KKSRGDYMTMQIG-CONH2 substrate after 60 mins by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Pharmadesign

Curated by ChEMBL
LigandPNGBDBM50344207(4-(6-nitroquinazolin-4-ylamino)phenol | CHEMBL1778...)
Affinity DataIC50: 8.66E+3nMAssay Description:Inhibition of ALK using FL-Peptide 13, 5-FAM-KKSRGDYMTMQIG-CONH2 substrate after 60 mins by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Pharmadesign

Curated by ChEMBL
LigandPNGBDBM50344206(2,6-dimethyl-4-((2-(thiophen-2-yl)-1H-pyrrolo[2,3-...)
Affinity DataIC50: 9.29E+3nMAssay Description:Inhibition of ALK using FL-Peptide 13, 5-FAM-KKSRGDYMTMQIG-CONH2 substrate after 60 mins by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed