Compile Data Set for Download or QSAR
Report error Found 28 Enz. Inhib. hit(s) with all data for entry = 50033505
TargetNitric oxide synthase, inducible(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50346533((S)-pyrrolidine-2-carboximidamide | CHEMBL1783098)
Affinity DataKd: >4.00E+4nMAssay Description:Binding affinity to human recombinant iNOS delta 65 residueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50346532((R)-pyrrolidine-2-carboximidamide | CHEMBL1783097)
Affinity DataKd:  630nMAssay Description:Binding affinity to human recombinant iNOS delta 65 residueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50346529(CHEMBL1783095 | CHEMBL1783094 | (R)-azetidine-2-ca...)
Affinity DataIC50: 30nMAssay Description:Inhibition of human recombinant iNOS by microtiter plate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50346532((R)-pyrrolidine-2-carboximidamide | CHEMBL1783097)
Affinity DataIC50: 120nMAssay Description:Inhibition of human recombinant iNOS by microtiter plate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50346528(2,5-dihydro-1H-pyrrole-2-carboximidamide | CHEMBL1...)
Affinity DataIC50: 180nMAssay Description:Inhibition of human recombinant iNOS by microtiter plate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50346529(CHEMBL1783095 | CHEMBL1783094 | (R)-azetidine-2-ca...)
Affinity DataIC50: 200nMAssay Description:Inhibition of human recombinant iNOS by microtiter plate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50346529(CHEMBL1783095 | CHEMBL1783094 | (R)-azetidine-2-ca...)
Affinity DataIC50: 250nMAssay Description:Inhibition of human recombinant eNOS by microtiter plate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50346529(CHEMBL1783095 | CHEMBL1783094 | (R)-azetidine-2-ca...)
Affinity DataIC50: 260nMAssay Description:Inhibition of human recombinant nNOS by microtiter plate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50346520(cyclobutanecarboximidamide | CHEMBL1783072)
Affinity DataIC50: 380nMAssay Description:Inhibition of human recombinant iNOS by microtiter plate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50346527(pyrrolidine-2-carboximidamide | CHEMBL1783092)
Affinity DataIC50: 700nMAssay Description:Inhibition of human recombinant iNOS by microtiter plate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50346519(cyclopropanecarboximidamide | CHEMBL1783071)
Affinity DataIC50: 790nMAssay Description:Inhibition of human recombinant iNOS by microtiter plate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50086467((S)-4-(2-Acetimidoylamino-ethylsulfanyl)-2-amino-b...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of human recombinant iNOS by microtiter plate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50346529(CHEMBL1783095 | CHEMBL1783094 | (R)-azetidine-2-ca...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of human recombinant nNOS by microtiter plate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50346529(CHEMBL1783095 | CHEMBL1783094 | (R)-azetidine-2-ca...)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of human recombinant eNOS by microtiter plate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50346521(cyclopentanecarboximidamide | CHEMBL1229853)
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibition of human recombinant iNOS by microtiter plate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50346526(tetrahydrothiophene-2-carboximidamide | CHEMBL1783...)
Affinity DataIC50: 5.30E+3nMAssay Description:Inhibition of human recombinant iNOS by microtiter plate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50346525(tetrahydrofuran-2-carboximidamide | CHEMBL1783090)
Affinity DataIC50: 8.90E+3nMAssay Description:Inhibition of human recombinant iNOS by microtiter plate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50346533((S)-pyrrolidine-2-carboximidamide | CHEMBL1783098)
Affinity DataIC50: 9.40E+3nMAssay Description:Inhibition of human recombinant iNOS by microtiter plate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50346531(azetidine-3-carboximidamide | CHEMBL1783096)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of human recombinant iNOS by microtiter plate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50346532((R)-pyrrolidine-2-carboximidamide | CHEMBL1783097)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of human recombinant nNOS by microtiter plate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50346532((R)-pyrrolidine-2-carboximidamide | CHEMBL1783097)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of human recombinant eNOS by microtiter plate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50346523(piperidine-3-carboximidamide | CHEMBL1783074)
Affinity DataIC50: 5.10E+4nMAssay Description:Inhibition of human recombinant iNOS by microtiter plate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50346524(piperidine-4-carboximidamide | CHEMBL1783089)
Affinity DataIC50: 5.80E+4nMAssay Description:Inhibition of human recombinant iNOS by microtiter plate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50346533((S)-pyrrolidine-2-carboximidamide | CHEMBL1783098)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant eNOS by microtiter plate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50346522(piperidine-2-carboximidamide | CHEMBL1783073)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant iNOS by microtiter plate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50346533((S)-pyrrolidine-2-carboximidamide | CHEMBL1783098)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant nNOS by microtiter plate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50086467((S)-4-(2-Acetimidoylamino-ethylsulfanyl)-2-amino-b...)
Affinity DataIC50: 1.45E+5nMAssay Description:Inhibition of human recombinant nNOS by microtiter plate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50086467((S)-4-(2-Acetimidoylamino-ethylsulfanyl)-2-amino-b...)
Affinity DataIC50: 4.66E+5nMAssay Description:Inhibition of human recombinant eNOS by microtiter plate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed