Compile Data Set for Download or QSAR
Report error Found 43 Enz. Inhib. hit(s) with all data for entry = 50033333
TargetSodium-dependent serotonin transporter(Rat)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM30130(Prozac | cid_62857 | Fluoxetin | CHEMBL41 | CHEMBL...)
Affinity DataKi:  12.2nMAssay Description:Inhibition of SERT in rat cerebral cortex assessed as [3H]serotonin accumulationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50343477((3S,6S)-6-Benzhydryl-N-(4-methoxybenzyl)tetrahydro...)
Affinity DataKi:  12.9nMAssay Description:Inhibition of SERT in rat cerebral cortex assessed as [3H]serotonin accumulationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50190609((2S,4R,5R)-5-(4-methoxybenzylamino)-2-benzhydryl-t...)
Affinity DataKi:  14.7nMAssay Description:Inhibition of SERT in rat cerebral cortex assessed as [3H]serotonin accumulationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50343477((3S,6S)-6-Benzhydryl-N-(4-methoxybenzyl)tetrahydro...)
Affinity DataKi:  15.9nMAssay Description:Inhibition of DAT in rat striatum assessed as [3H]dopamine accumulationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM22165(Vanoxerine | CHEMBL542933 | GBR-12909 | CHEMBL5438...)
Affinity DataKi:  16.2nMAssay Description:Inhibition of DAT in rat striatum assessed as [3H]dopamine accumulationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetSodium-dependent serotonin transporter(Rat)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50190601((2S,4R,5R)-2-benzhydryl-5-[(1H-indol-5-ylmethyl)-a...)
Affinity DataKi:  25nMAssay Description:Inhibition of SERT in rat cerebral cortex assessed as [3H]serotonin accumulationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50343470((3S,6S)-6-Benzhydryl-N-(pyridin-4-ylmethyl)tetrahy...)
Affinity DataKi:  28.3nMAssay Description:Inhibition of DAT in rat striatum assessed as [3H]dopamine accumulationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50190603(cis-(3S,6S)-(6-benzhydryl-tetrahydropyran-3-yl)-(4...)
Affinity DataKi:  29.1nMAssay Description:Inhibition of SERT in rat cerebral cortex assessed as [3H]serotonin accumulationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50343473(3-((((3S,6S)-6-Benzhydryltetrahydro-2H-pyran-3-yl)...)
Affinity DataKi:  31.3nMAssay Description:Inhibition of DAT in rat striatum assessed as [3H]dopamine accumulationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50190609((2S,4R,5R)-5-(4-methoxybenzylamino)-2-benzhydryl-t...)
Affinity DataKi:  37.4nMAssay Description:Inhibition of DAT in rat striatum assessed as [3H]dopamine accumulationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50343473(3-((((3S,6S)-6-Benzhydryltetrahydro-2H-pyran-3-yl)...)
Affinity DataKi:  40.1nMAssay Description:Inhibition of SERT in rat cerebral cortex assessed as [3H]serotonin accumulationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50343474((3S,6S)-6-Benzhydryl-N-(thiophen-2-ylmethyl)tetrah...)
Affinity DataKi:  41.4nMAssay Description:Inhibition of DAT in rat striatum assessed as [3H]dopamine accumulationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50190603(cis-(3S,6S)-(6-benzhydryl-tetrahydropyran-3-yl)-(4...)
Affinity DataKi:  42nMAssay Description:Inhibition of DAT in rat striatum assessed as [3H]dopamine accumulationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50343476((3S,6S)-N-((1H-Pyrrol-2-yl)methyl)-6-benzhydryltet...)
Affinity DataKi:  43.2nMAssay Description:Inhibition of DAT in rat striatum assessed as [3H]dopamine accumulationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50343463((S)-2-((3S,6S)-6-Benzhydryltetrahydro-2H-pyran-3-y...)
Affinity DataKi:  54nMAssay Description:Inhibition of DAT in rat striatum assessed as [3H]dopamine accumulationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50343464((R)-2-(3S,6S)-6-Benzhydryltetrahydro-2H-pyran-3-yl...)
Affinity DataKi:  71.8nMAssay Description:Inhibition of DAT in rat striatum assessed as [3H]dopamine accumulationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50190601((2S,4R,5R)-2-benzhydryl-5-[(1H-indol-5-ylmethyl)-a...)
Affinity DataKi:  85.2nMAssay Description:Inhibition of DAT in rat striatum assessed as [3H]dopamine accumulationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50343471((3S,6S)-6-Benzhydryl-N-(naphthalen-1-ylmethyl)tetr...)
Affinity DataKi:  88.8nMAssay Description:Inhibition of SERT in rat cerebral cortex assessed as [3H]serotonin accumulationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50343465((S)-2-(((3S,6S)-6-Benzhydryltetrahydro-2H-pyran-3-...)
Affinity DataKi:  106nMAssay Description:Inhibition of DAT in rat striatum assessed as [3H]dopamine accumulationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50343475((3S,6S)-6-Benzhydryl-N-(furan-2-ylmethyl)tetrahydr...)
Affinity DataKi:  110nMAssay Description:Inhibition of DAT in rat striatum assessed as [3H]dopamine accumulationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50343475((3S,6S)-6-Benzhydryl-N-(furan-2-ylmethyl)tetrahydr...)
Affinity DataKi:  115nMAssay Description:Inhibition of SERT in rat cerebral cortex assessed as [3H]serotonin accumulationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50343466((R)-2-((3S,6S)-6-Benzhydryltetrahydro-2H-pyran-3-y...)
Affinity DataKi:  125nMAssay Description:Inhibition of DAT in rat striatum assessed as [3H]dopamine accumulationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50343467((S)-2-(((3S,6S)-6-Benzhydryltetrahydro-2H-pyran-3-...)
Affinity DataKi:  137nMAssay Description:Inhibition of DAT in rat striatum assessed as [3H]dopamine accumulationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50343476((3S,6S)-N-((1H-Pyrrol-2-yl)methyl)-6-benzhydryltet...)
Affinity DataKi:  141nMAssay Description:Inhibition of SERT in rat cerebral cortex assessed as [3H]serotonin accumulationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50343469((3S,6S)-6-Benzhydryl-N-(pyridin-3-ylmethyl)tetrahy...)
Affinity DataKi:  145nMAssay Description:Inhibition of DAT in rat striatum assessed as [3H]dopamine accumulationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50343462((R)-2-((3S,6S)-6-Benzhydryltetrahydro-2Hpyran-3-yl...)
Affinity DataKi:  145nMAssay Description:Inhibition of DAT in rat striatum assessed as [3H]dopamine accumulationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50343469((3S,6S)-6-Benzhydryl-N-(pyridin-3-ylmethyl)tetrahy...)
Affinity DataKi:  152nMAssay Description:Inhibition of SERT in rat cerebral cortex assessed as [3H]serotonin accumulationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50343474((3S,6S)-6-Benzhydryl-N-(thiophen-2-ylmethyl)tetrah...)
Affinity DataKi:  186nMAssay Description:Inhibition of SERT in rat cerebral cortex assessed as [3H]serotonin accumulationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM22165(Vanoxerine | CHEMBL542933 | GBR-12909 | CHEMBL5438...)
Affinity DataKi:  198nMAssay Description:Inhibition of SERT in rat cerebral cortex assessed as [3H]serotonin accumulationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50343472(2-(((3S,6S)-6-Benzhydryltetrahydro-2H-pyran-3-ylam...)
Affinity DataKi:  200nMAssay Description:Inhibition of DAT in rat striatum assessed as [3H]dopamine accumulationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50343468((3S,6S)-6-Benzhydryl-N-(pyridin-2-ylmethyl)tetrahy...)
Affinity DataKi:  209nMAssay Description:Inhibition of DAT in rat striatum assessed as [3H]dopamine accumulationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50343472(2-(((3S,6S)-6-Benzhydryltetrahydro-2H-pyran-3-ylam...)
Affinity DataKi:  440nMAssay Description:Inhibition of SERT in rat cerebral cortex assessed as [3H]serotonin accumulationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50343471((3S,6S)-6-Benzhydryl-N-(naphthalen-1-ylmethyl)tetr...)
Affinity DataKi:  473nMAssay Description:Inhibition of DAT in rat striatum assessed as [3H]dopamine accumulationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50343468((3S,6S)-6-Benzhydryl-N-(pyridin-2-ylmethyl)tetrahy...)
Affinity DataKi:  483nMAssay Description:Inhibition of SERT in rat cerebral cortex assessed as [3H]serotonin accumulationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50124566(2-[(2-Ethoxy-phenoxy)-phenyl-methyl]-morpholine | ...)
Affinity DataKi:  503nMAssay Description:Inhibition of SERT in rat cerebral cortex assessed as [3H]serotonin accumulationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50343467((S)-2-(((3S,6S)-6-Benzhydryltetrahydro-2H-pyran-3-...)
Affinity DataKi:  646nMAssay Description:Inhibition of SERT in rat cerebral cortex assessed as [3H]serotonin accumulationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50343463((S)-2-((3S,6S)-6-Benzhydryltetrahydro-2H-pyran-3-y...)
Affinity DataKi:  796nMAssay Description:Inhibition of SERT in rat cerebral cortex assessed as [3H]serotonin accumulationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50343465((S)-2-(((3S,6S)-6-Benzhydryltetrahydro-2H-pyran-3-...)
Affinity DataKi:  825nMAssay Description:Inhibition of SERT in rat cerebral cortex assessed as [3H]serotonin accumulationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50343470((3S,6S)-6-Benzhydryl-N-(pyridin-4-ylmethyl)tetrahy...)
Affinity DataKi:  889nMAssay Description:Inhibition of SERT in rat cerebral cortex assessed as [3H]serotonin accumulationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50343462((R)-2-((3S,6S)-6-Benzhydryltetrahydro-2Hpyran-3-yl...)
Affinity DataKi:  936nMAssay Description:Inhibition of SERT in rat cerebral cortex assessed as [3H]serotonin accumulationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50343466((R)-2-((3S,6S)-6-Benzhydryltetrahydro-2H-pyran-3-y...)
Affinity DataKi:  1.09E+3nMAssay Description:Inhibition of SERT in rat cerebral cortex assessed as [3H]serotonin accumulationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM30130(Prozac | cid_62857 | Fluoxetin | CHEMBL41 | CHEMBL...)
Affinity DataKi:  1.09E+3nMAssay Description:Inhibition of DAT in rat striatum assessed as [3H]dopamine accumulationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50343464((R)-2-(3S,6S)-6-Benzhydryltetrahydro-2H-pyran-3-yl...)
Affinity DataKi:  1.14E+3nMAssay Description:Inhibition of SERT in rat cerebral cortex assessed as [3H]serotonin accumulationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed