Compile Data Set for Download or QSAR
Report error Found 27 Enz. Inhib. hit(s) with all data for entry = 50033249
TargetCytochrome P450 26A1(Human)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50342130(3-[4-(6-Hydroxy-naphthalen-2-ylamino)-phenyl]-3-im...)
Affinity DataIC50: 3nMAssay Description:Inhibition of CYP26A1 in human MCF7 cell microsomes using [3H]ATRA after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 26A1(Human)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50342128(3-Imidazol-1-yl-2-methyl-3-[4-(naphthalen-2-ylamin...)
Affinity DataIC50: 3nMAssay Description:Inhibition of CYP26A1 in human MCF7 cell microsomes using [3H]ATRA after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 26A1(Human)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50342143(3-Imidazol-1-yl-2,2-dimethyl-3-[4-(naphthalen-1-yl...)
Affinity DataIC50: 6nMAssay Description:Inhibition of CYP26A1 in human MCF7 cell microsomes using [3H]ATRA after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 26A1(Human)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50342129(3-Imidazol-1-yl-3-[4-(6-methoxy-naphthalen-2-ylami...)
Affinity DataIC50: 8nMAssay Description:Inhibition of CYP26A1 in human MCF7 cell microsomes using [3H]ATRA after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 26A1(Human)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50342141(3-[4-(Benzo[1,3]dioxol-5-ylamino)-phenyl]-3-imidaz...)
Affinity DataIC50: 8nMAssay Description:Inhibition of CYP26A1 in human MCF7 cell microsomes using [3H]ATRA after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 26A1(Human)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50342131(3-[4-(Benzooxazol-2-ylamino)-phenyl]-3-imidazol-1-...)
Affinity DataIC50: 10nMAssay Description:Inhibition of CYP26A1 in human MCF7 cell microsomes using [3H]ATRA after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 26A1(Human)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50342133(Benzothiazol-2-yl-[4-((1S,2S)-2-dimethylamino-1-im...)
Affinity DataIC50: 10nMAssay Description:Inhibition of CYP26A1 in human MCF7 cell microsomes using [3H]ATRA after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 26A1(Human)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50342140(3-Imidazol-1-yl-2,2-dimethyl-3-(4-phenylaminopheny...)
Affinity DataIC50: 10nMAssay Description:Inhibition of CYP26A1 in human MCF7 cell microsomes using [3H]ATRA after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 26A1(Human)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50342135(Methyl syn-3-(1H-1-Imidazolyl)-3-[4-(phenylamino)p...)
Affinity DataIC50: 26nMAssay Description:Inhibition of CYP26A1 in human MCF7 cell microsomes using [3H]ATRA after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 26A1(Human)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50342134(Methyl anti-3-(1H-1-Imidazolyl)-3-[4-(phenylamino)...)
Affinity DataIC50: 40nMAssay Description:Inhibition of CYP26A1 in human MCF7 cell microsomes using [3H]ATRA after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 26A1(Human)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50342137(Methyl syn-3-(1H-1-Imidazolyl)-3-[4-(2-naphthylami...)
Affinity DataIC50: 50nMAssay Description:Inhibition of CYP26A1 in human MCF7 cell microsomes using [3H]ATRA after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 26A1(Human)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50342132(3-[4-(Benzothiazol-2-ylamino)-phenyl]-3-imidazol-1...)
Affinity DataIC50: 100nMAssay Description:Inhibition of CYP26A1 in human MCF7 cell microsomes using [3H]ATRA after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 26A1(Human)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50342144(3-[4-(2-Ethoxy-naphthalen-1-ylamino)-phenyl]-3-imi...)
Affinity DataIC50: 125nMAssay Description:Inhibition of CYP26A1 in human MCF7 cell microsomes using [3H]ATRA after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 26A1(Human)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50342136(Methyl anti-3-(1H-1-Imidazolyl)-3-[4-(2-naphthylam...)
Affinity DataIC50: 140nMAssay Description:Inhibition of CYP26A1 in human MCF7 cell microsomes using [3H]ATRA after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 26A1(Human)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50342142(3-[4-(Biphenyl-4-ylamino)-phenyl]-3-imidazol-1-yl-...)
Affinity DataIC50: 250nMAssay Description:Inhibition of CYP26A1 in human MCF7 cell microsomes using [3H]ATRA after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2C19(Human)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50342133(Benzothiazol-2-yl-[4-((1S,2S)-2-dimethylamino-1-im...)
Affinity DataIC50: 350nMAssay Description:Inhibition of CYP2C19 in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 26A1(Human)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50176808(6-((3-chlorophenyl)(1H-imidazol-1-yl)methyl)-1H-be...)
Affinity DataIC50: 540nMAssay Description:Inhibition of CYP26A1 in human MCF7 cell microsomes using [3H]ATRA after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2D6(Human)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50342128(3-Imidazol-1-yl-2-methyl-3-[4-(naphthalen-2-ylamin...)
Affinity DataIC50: 600nMAssay Description:Inhibition of CYP2D6 in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 26A1(Human)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50342139(3-Imidazol-1-yl-2,2-dimethyl-3-(4-naphthalen-2-ylm...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of CYP26A1 in human MCF7 cell microsomes using [3H]ATRA after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 26A1(Human)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50342138(Methyl 3-(1H-Imidazol-1-yl)-2,3-dimethyl-3-((4-nap...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of CYP26A1 in human MCF7 cell microsomes using [3H]ATRA after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 1A2(Human)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50342128(3-Imidazol-1-yl-2-methyl-3-[4-(naphthalen-2-ylamin...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of CYP1A2 in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2C9(Human)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50342128(3-Imidazol-1-yl-2-methyl-3-[4-(naphthalen-2-ylamin...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of CYP2C9 in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2D6(Human)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50342133(Benzothiazol-2-yl-[4-((1S,2S)-2-dimethylamino-1-im...)
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibition of CYP2D6 in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2C9(Human)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50342133(Benzothiazol-2-yl-[4-((1S,2S)-2-dimethylamino-1-im...)
Affinity DataIC50: 5.90E+3nMAssay Description:Inhibition of CYP2C9 in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 3A4(Human)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50342128(3-Imidazol-1-yl-2-methyl-3-[4-(naphthalen-2-ylamin...)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of CYP3A4 in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 1A2(Human)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50342133(Benzothiazol-2-yl-[4-((1S,2S)-2-dimethylamino-1-im...)
Affinity DataIC50: 8.30E+3nMAssay Description:Inhibition of CYP1A2 in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 3A4(Human)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50342133(Benzothiazol-2-yl-[4-((1S,2S)-2-dimethylamino-1-im...)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed