Compile Data Set for Download or QSAR
Report error Found 68 Enz. Inhib. hit(s) with all data for entry = 50033243
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50341988((3S)-4-((2S)-1-amino-3-(4-((((4-chlorobutyl)(methy...)
Affinity DataIC50: 20nMAssay Description:Inhibition of PTP1BMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetM-phase inducer phosphatase 1(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50208827(NSC-95397 | cid_262093 | N1786 (NSC95397) | CHEMBL...)
Affinity DataIC50: 22nMAssay Description:Inhibition of human Cdc25AMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50341990((S)-2-[2-(4-Methoxy-phenyl)-acetylamino]-N-{(S)-1-...)
Affinity DataIC50: 40nMAssay Description:Inhibition of PTP1BMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetM-phase inducer phosphatase 3(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50208827(NSC-95397 | cid_262093 | N1786 (NSC95397) | CHEMBL...)
Affinity DataIC50: 56.9nMAssay Description:Inhibition of human Cdc25CMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDual specificity protein phosphatase 3(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50303174(cid_3823393 | CHEMBL584481 | 2-(5-((3-(4-(2-fluoro...)
Affinity DataIC50: 74nMAssay Description:Inhibition of VHRMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50308840(5-[2-Hydroxy-5-(1H-pyrrol-2-yl)-phenyl]-1,1-dioxo-...)
Affinity DataIC50: 80nMAssay Description:Inhibition of PTP1BMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50239833((3-bromo-7-cyanonaphthalen-2-yl)difluoromethylphos...)
Affinity DataIC50: 120nMAssay Description:Inhibition of PTP1BMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetM-phase inducer phosphatase 2(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50208827(NSC-95397 | cid_262093 | N1786 (NSC95397) | CHEMBL...)
Affinity DataIC50: 125nMAssay Description:Inhibition of human Cdc25BMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50308839(5-[3'-(6-Fluoro-2,3-dihydro-indol-1-yl)-biphenyl-4...)
Affinity DataIC50: 130nMAssay Description:Inhibition of PTP1BMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50308846(N-{(S)-1-(1H-Benzoimidazol-2-yl)-2-[3-methyl-4-(1,...)
Affinity DataIC50: 140nMAssay Description:Inhibition of PTP1BMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetM-phase inducer phosphatase 3(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50341995(5-(2-(dimethylamino)ethylamino)-2,6-dimethylbenzo[...)
Affinity DataIC50: 170nMAssay Description:Inhibition of human Cdc25CMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50341994(2-(((5-tert-butylthiazol-2-yl)methyl)((4-(4-((4-(h...)
Affinity DataIC50: 220nMAssay Description:Inhibition of PTP1BMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTYR_PHOSPHATASE_2 domain-containing protein(Mycobacterium tuberculosis (strain CDC 1551 / Oshk...)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM26104(5-{2-cyclohexyl-4-[4-fluoro-3-(trifluoromethyl)phe...)
Affinity DataIC50: 220nMAssay Description:Inhibition of Mycobacterium tuberculosis ptpBMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50341993(4-((3-((3-(4-carboxybenzyl)-4-oxo-2-(phenylimino)t...)
Affinity DataIC50: 220nMAssay Description:Inhibition of PTP1BMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetM-phase inducer phosphatase 1(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50341995(5-(2-(dimethylamino)ethylamino)-2,6-dimethylbenzo[...)
Affinity DataIC50: 250nMAssay Description:Inhibition of human Cdc25AMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetM-phase inducer phosphatase 2(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50341995(5-(2-(dimethylamino)ethylamino)-2,6-dimethylbenzo[...)
Affinity DataIC50: 250nMAssay Description:Inhibition of human Cdc25BMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50342003(NSC-87877 | disodium 8-hydroxy-7-[(E)-(6-sulfonato...)
Affinity DataIC50: 320nMAssay Description:Inhibition of SHP-2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTYR_PHOSPHATASE_2 domain-containing protein(Mycobacterium tuberculosis (strain CDC 1551 / Oshk...)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50341985(CHEMBL1765366)
Affinity DataIC50: 320nMAssay Description:Inhibition of Mycobacterium tuberculosis ptpBMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTYR_PHOSPHATASE_2 domain-containing protein(Mycobacterium tuberculosis (strain CDC 1551 / Oshk...)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50341979(5-(Biphenyl-4-carbonyl)-1,3,4,5-tetrahydro-thiopyr...)
Affinity DataIC50: 360nMAssay Description:Inhibition of Mycobacterium tuberculosis ptpBMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTYR_PHOSPHATASE_2 domain-containing protein(Mycobacterium tuberculosis (strain CDC 1551 / Oshk...)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50341980(3-Benzyl-1-(biphenyl-4-carbonyl)-2-methyl-1H-indol...)
Affinity DataIC50: 430nMAssay Description:Inhibition of Mycobacterium tuberculosis ptpBMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTYR_PHOSPHATASE_2 domain-containing protein(Mycobacterium tuberculosis (strain CDC 1551 / Oshk...)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50341981(2-((3-chlorobenzyl)((5-(N-(3,3-diphenylpropyl)sulf...)
Affinity DataIC50: 440nMAssay Description:Inhibition of Mycobacterium tuberculosis ptpBMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetM-phase inducer phosphatase 1(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50342000(4-((S)-2-((1R,3aS,4S,7aR)-4,7a-dimethyl-1-((R)-6-m...)
Affinity DataIC50: 440nMAssay Description:Inhibition of human Cdc25AMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTYR_PHOSPHATASE_2 domain-containing protein(Mycobacterium tuberculosis (strain CDC 1551 / Oshk...)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50341982(5-(2-cyclohexyl-4-((1-(6-(4-fluoro-2-methylphenyls...)
Affinity DataIC50: 640nMAssay Description:Inhibition of Mycobacterium tuberculosis ptpBMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetM-phase inducer phosphatase 1(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50253622(cid_1383304 | CHEMBL459929 | 2-[4-(4-chlorophenyl)...)
Affinity DataIC50: 800nMAssay Description:Inhibition of human Cdc25AMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetM-phase inducer phosphatase 1(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50341999((R)-5-hydroxy-4-(2-((1R,2R,5S,8aS)-1,2,5-trimethyl...)
Affinity DataIC50: 800nMAssay Description:Inhibition of human Cdc25AMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM84499(CHEMBL1765359 | 2-(5-{1-[(2Z)-2H-pyrrol-2-ylidene]...)
Affinity DataIC50: 900nMAssay Description:Inhibition of Mycobacterium tuberculosis ptpAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein tyrosine phosphatase type IVA 3(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50184288(5-(2-(2-bromobenzyloxy)-5-bromobenzylidene)-2-thio...)
Affinity DataIC50: 900nMAssay Description:Inhibition of PRL-3More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetM-phase inducer phosphatase 1(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50342001(1-(biphenyl-4-yl)-3,4-bis(2-hydroxyethylthio)-1H-p...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human Cdc25AMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTYR_PHOSPHATASE_2 domain-containing protein(Mycobacterium tuberculosis (strain CDC 1551 / Oshk...)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50341978((4S,6S,12bR)-4-(4-bromophenyl)-2-chloro-12-(2,3-di...)
Affinity DataIC50: 1.13E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis ptpBMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTYR_PHOSPHATASE_2 domain-containing protein(Mycobacterium tuberculosis (strain CDC 1551 / Oshk...)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50341986(6-hydroxy-3-(1-(2-(4-morpholinophenylamino)-2-oxoe...)
Affinity DataIC50: 1.26E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis ptpBMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50333649((3R,6R)-6-((3S,5R,7R,8R,9S,10S,13R,14S,17R)-3-(3-(...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of PTP1BMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50209683((R)-2-(4-(9-bromo-2,3-dimethylnaphtho[2,3-b]thioph...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of PTP1BMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDual specificity protein phosphatase 3(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50342005((5R)-2-((3S)-1-(((R)-3-hydroxy-5-oxo-4-palmitoyl-2...)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of VHRMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetM-phase inducer phosphatase 2(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50342000(4-((S)-2-((1R,3aS,4S,7aR)-4,7a-dimethyl-1-((R)-6-m...)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of human Cdc25BMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetM-phase inducer phosphatase 1(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50341996((2R,3R)-2,3-Dibromo-3-methyl-1,1-dioxo-1lambda*6*-...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human Cdc25AMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetM-phase inducer phosphatase 2(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50253622(cid_1383304 | CHEMBL459929 | 2-[4-(4-chlorophenyl)...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human Cdc25BMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50166435(5-(4-METHOXYBIPHENYL-3-YL)-1,2,5-THIADIAZOLIDIN-3-...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of PTP1BMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50342002((2S,3aR,6S,6aR)-N-(cyclohexylmethyl)-6-(5-((R)-3-(...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of SHP-2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM84499(CHEMBL1765359 | 2-(5-{1-[(2Z)-2H-pyrrol-2-ylidene]...)
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of PTP1BMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetM-phase inducer phosphatase 2(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50197854(3-(4-heptadecyl-2,5-dioxo-2,5-dihydrofuran-3-yl)pr...)
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of human Cdc25BMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetM-phase inducer phosphatase 3(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50197854(3-(4-heptadecyl-2,5-dioxo-2,5-dihydrofuran-3-yl)pr...)
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of human Cdc25CMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetM-phase inducer phosphatase 1(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50197854(3-(4-heptadecyl-2,5-dioxo-2,5-dihydrofuran-3-yl)pr...)
Affinity DataIC50: 5.10E+3nMAssay Description:Inhibition of human Cdc25AMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetM-phase inducer phosphatase 1(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50341998(5-hydroxy-4-((S)-1-hydroxy-2-((1R,2R,5S,8aS)-1,2,5...)
Affinity DataIC50: 5.10E+3nMAssay Description:Inhibition of human Cdc25AMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTYR_PHOSPHATASE_2 domain-containing protein(Mycobacterium tuberculosis (strain CDC 1551 / Oshk...)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50341983(CHEMBL1765364)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis ptpBMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50341989(3-(3,5-DIBROMO-4-HYDROXY-BENZOYL)-2-ETHYL-BENZOFUR...)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of PTP1BMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetM-phase inducer phosphatase 1(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50341997(Dysidiolide | CHEMBL1765353)
Affinity DataIC50: 9.40E+3nMAssay Description:Inhibition of human Cdc25AMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTYR_PHOSPHATASE_2 domain-containing protein(Mycobacterium tuberculosis (strain CDC 1551 / Oshk...)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50341984(CHEMBL1765365)
Affinity DataIC50: 9.60E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis ptpBMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetM-phase inducer phosphatase 2(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50342001(1-(biphenyl-4-yl)-3,4-bis(2-hydroxyethylthio)-1H-p...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human Cdc25BMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50115579(CHEMBL16326 | (Z)-2-hydroxy-4-oxo-4-phenyl-but-2-e...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of PTP1BMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50152579(4-(2-Fluoro-phenyl)-2,4-dioxo-butyric acid | CHEMB...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of PTP1BMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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