Compile Data Set for Download or QSAR
Report error Found 24 Enz. Inhib. hit(s) with all data for entry = 50033135
TargetCholinesterase(Horse)
University of Sfax

Curated by ChEMBL
LigandPNGBDBM8961(CHEMBL95 | Cognex | cid_1935 | CHEMBL1337960 | 1,2...)
Affinity DataIC50: 5.20nMAssay Description:Inhibition of horse serum butyrylcholinesterase preincubated with compound for 10 mins using butrylcholine iodide as substrate after 15 mins by spect...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetAcetylcholinesterase(Electric eel)
University of Sfax

Curated by ChEMBL
LigandPNGBDBM50340109(rac-4-[(13-Amino-10,11,12,14-tetrahydro-9H-benzo[5...)
Affinity DataIC50: 7nMAssay Description:Inhibition of Electrophorus electricus acetylcholinesterase preincubated with compound for 10 mins using acetylcholine iodide as substrate after 15 m...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Sfax

Curated by ChEMBL
LigandPNGBDBM50340111(rac-14-(3'-Methoxyphenyl)-10,11,12,14-tetrahydro-9...)
Affinity DataIC50: 16nMAssay Description:Inhibition of Electrophorus electricus acetylcholinesterase preincubated with compound for 10 mins using acetylcholine iodide as substrate after 15 m...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Sfax

Curated by ChEMBL
LigandPNGBDBM50340110(rac-14-(4'-Methoxyphenyl)-10,11,12,14-tetrahydro-9...)
Affinity DataIC50: 18nMAssay Description:Inhibition of Electrophorus electricus acetylcholinesterase preincubated with compound for 10 mins using acetylcholine iodide as substrate after 15 m...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Sfax

Curated by ChEMBL
LigandPNGBDBM50340112(rac-14-(2'-Methoxyphenyl)-10,11,12,14-tetrahydro-9...)
Affinity DataIC50: 20nMAssay Description:Inhibition of Electrophorus electricus acetylcholinesterase preincubated with compound for 10 mins using acetylcholine iodide as substrate after 15 m...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Sfax

Curated by ChEMBL
LigandPNGBDBM50340115(rac-14-(3',4'-Dimethoxyphenyl)-10,11,12,14-tetrahy...)
Affinity DataIC50: 26nMAssay Description:Inhibition of Electrophorus electricus acetylcholinesterase preincubated with compound for 10 mins using acetylcholine iodide as substrate after 15 m...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Sfax

Curated by ChEMBL
LigandPNGBDBM50340116(rac-14-(3',4',5'-Trimethoxyphenyl)-10,11,12,14-tet...)
Affinity DataIC50: 26nMAssay Description:Inhibition of Electrophorus electricus acetylcholinesterase preincubated with compound for 10 mins using acetylcholine iodide as substrate after 15 m...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Sfax

Curated by ChEMBL
LigandPNGBDBM8961(CHEMBL95 | Cognex | cid_1935 | CHEMBL1337960 | 1,2...)
Affinity DataIC50: 27nMAssay Description:Inhibition of Electrophorus electricus acetylcholinesterase preincubated with compound for 10 mins using acetylcholine iodide as substrate after 15 m...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Sfax

Curated by ChEMBL
LigandPNGBDBM50340114(rac-4-[13-Amino-10,11,12,14-tetrahydro-9H-benzo[5,...)
Affinity DataIC50: 28nMAssay Description:Inhibition of Electrophorus electricus acetylcholinesterase preincubated with compound for 10 mins using acetylcholine iodide as substrate after 15 m...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Sfax

Curated by ChEMBL
LigandPNGBDBM50340108(rac-14-(4'-Methylphenyl)-10,11,12,14-tetrahydro-9H...)
Affinity DataIC50: 43nMAssay Description:Inhibition of Electrophorus electricus acetylcholinesterase preincubated with compound for 10 mins using acetylcholine iodide as substrate after 15 m...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Sfax

Curated by ChEMBL
LigandPNGBDBM50340113(rac-4-[12-Amino-9,10,11,13-tetrahydrobenzo[5,6]chr...)
Affinity DataIC50: 101nMAssay Description:Inhibition of Electrophorus electricus acetylcholinesterase preincubated with compound for 10 mins using acetylcholine iodide as substrate after 15 m...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Sfax

Curated by ChEMBL
LigandPNGBDBM50340117(rac-14-(4'-Nitrophenyl)-10,11,12,14-tetrahydro-9H-...)
Affinity DataIC50: 170nMAssay Description:Inhibition of Electrophorus electricus acetylcholinesterase preincubated with compound for 10 mins using acetylcholine iodide as substrate after 15 m...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Sfax

Curated by ChEMBL
LigandPNGBDBM50241346(ethyl 5-amino-4-(4-methoxyphenyl)-2-methyl-6,7,8,9...)
Affinity DataIC50: 868nMAssay Description:Inhibition of Electrophorus electricus acetylcholinesterase preincubated with compound for 10 mins using acetylcholine iodide as substrate after 15 m...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCholinesterase(Horse)
University of Sfax

Curated by ChEMBL
LigandPNGBDBM50340108(rac-14-(4'-Methylphenyl)-10,11,12,14-tetrahydro-9H...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of horse serum butyrylcholinesterase preincubated with compound for 10 mins using butrylcholine iodide as substrate after 15 mins by spect...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCholinesterase(Horse)
University of Sfax

Curated by ChEMBL
LigandPNGBDBM50340117(rac-14-(4'-Nitrophenyl)-10,11,12,14-tetrahydro-9H-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of horse serum butyrylcholinesterase preincubated with compound for 10 mins using butrylcholine iodide as substrate after 15 mins by spect...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCholinesterase(Horse)
University of Sfax

Curated by ChEMBL
LigandPNGBDBM50340116(rac-14-(3',4',5'-Trimethoxyphenyl)-10,11,12,14-tet...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of horse serum butyrylcholinesterase preincubated with compound for 10 mins using butrylcholine iodide as substrate after 15 mins by spect...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCholinesterase(Horse)
University of Sfax

Curated by ChEMBL
LigandPNGBDBM50340115(rac-14-(3',4'-Dimethoxyphenyl)-10,11,12,14-tetrahy...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of horse serum butyrylcholinesterase preincubated with compound for 10 mins using butrylcholine iodide as substrate after 15 mins by spect...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCholinesterase(Horse)
University of Sfax

Curated by ChEMBL
LigandPNGBDBM50340114(rac-4-[13-Amino-10,11,12,14-tetrahydro-9H-benzo[5,...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of horse serum butyrylcholinesterase preincubated with compound for 10 mins using butrylcholine iodide as substrate after 15 mins by spect...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCholinesterase(Horse)
University of Sfax

Curated by ChEMBL
LigandPNGBDBM50340113(rac-4-[12-Amino-9,10,11,13-tetrahydrobenzo[5,6]chr...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of horse serum butyrylcholinesterase preincubated with compound for 10 mins using butrylcholine iodide as substrate after 15 mins by spect...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCholinesterase(Horse)
University of Sfax

Curated by ChEMBL
LigandPNGBDBM50340112(rac-14-(2'-Methoxyphenyl)-10,11,12,14-tetrahydro-9...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of horse serum butyrylcholinesterase preincubated with compound for 10 mins using butrylcholine iodide as substrate after 15 mins by spect...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCholinesterase(Horse)
University of Sfax

Curated by ChEMBL
LigandPNGBDBM50340111(rac-14-(3'-Methoxyphenyl)-10,11,12,14-tetrahydro-9...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of horse serum butyrylcholinesterase preincubated with compound for 10 mins using butrylcholine iodide as substrate after 15 mins by spect...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCholinesterase(Horse)
University of Sfax

Curated by ChEMBL
LigandPNGBDBM50340110(rac-14-(4'-Methoxyphenyl)-10,11,12,14-tetrahydro-9...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of horse serum butyrylcholinesterase preincubated with compound for 10 mins using butrylcholine iodide as substrate after 15 mins by spect...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCholinesterase(Horse)
University of Sfax

Curated by ChEMBL
LigandPNGBDBM50340109(rac-4-[(13-Amino-10,11,12,14-tetrahydro-9H-benzo[5...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of horse serum butyrylcholinesterase preincubated with compound for 10 mins using butrylcholine iodide as substrate after 15 mins by spect...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Sfax

Curated by ChEMBL
LigandPNGBDBM50340109(rac-4-[(13-Amino-10,11,12,14-tetrahydro-9H-benzo[5...)
Affinity DataKi:  5nMAssay Description:Mixed inhibition of Electrophorus electricus acetylcholinesterase using acetylcholine as substrate by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed