Compile Data Set for Download or QSAR
Report error Found 11 Enz. Inhib. hit(s) with all data for entry = 50033057
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
University of Missouri-Columbia

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  0.830nMAssay Description:Displacement of [3H]-(+)-pentazocine from Sigma1-receptor in guinea pig brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
University of Missouri-Columbia

Curated by ChEMBL
LigandPNGBDBM50338990(CHEMBL2311153 | N-phenylpropyl-N''-3,4-dimethoxyph...)
Affinity DataKi:  4.34nMAssay Description:Displacement of [3H]-(+)-pentazocine from Sigma1-receptor in guinea pig brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
University of Missouri-Columbia

Curated by ChEMBL
LigandPNGBDBM50338989(5-Bromo-N-(4-((3,4-dimethoxyphenethyl)(methyl)-ami...)
Affinity DataKi:  583nMAssay Description:Displacement of [3H]-(+)-pentazocine from Sigma1-receptor in guinea pig brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
University of Missouri-Columbia

Curated by ChEMBL
LigandPNGBDBM50206199(N-(4-(3,4-dimethoxyphenethylamino)butyl)-5-bromo-2...)
Affinity DataKi:  880nMAssay Description:Displacement of [3H]-(+)-pentazocine from Sigma1-receptor in guinea pig brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
University of Missouri-Columbia

Curated by ChEMBL
LigandPNGBDBM50137618(5-Bromo-N-[4-(6,7-dimethoxy-3,4-dihydro-1H-isoquin...)
Affinity DataKi:  881nMAssay Description:Displacement of [3H]-(+)-pentazocine from Sigma1-receptor in guinea pig brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
University of Missouri-Columbia

Curated by ChEMBL
LigandPNGBDBM50338983(5-Bromo-N-(4-(5,6-dimethoxyisoindolin-2-yl)butyl)-...)
Affinity DataKi:  1.44E+3nMAssay Description:Displacement of [3H]-(+)-pentazocine from Sigma1-receptor in guinea pig brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
University of Missouri-Columbia

Curated by ChEMBL
LigandPNGBDBM50338986(5-Bromo-N-(4-(7,8-dimethoxy-4,5-dihydro-1H-benzo[c...)
Affinity DataKi:  2.07E+3nMAssay Description:Displacement of [3H]-(+)-pentazocine from Sigma1-receptor in guinea pig brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
University of Missouri-Columbia

Curated by ChEMBL
LigandPNGBDBM50338987(5-Bromo-N-(4-(7,8-dimethoxy-2,3,4,5-tetrahydro-1Hb...)
Affinity DataKi:  2.56E+3nMAssay Description:Displacement of [3H]-(+)-pentazocine from Sigma1-receptor in guinea pig brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
University of Missouri-Columbia

Curated by ChEMBL
LigandPNGBDBM50338988(5-Bromo-N-(4-(6,7-dimethoxy-3,4-dihydroquinolin-1(...)
Affinity DataKi:  4.50E+3nMAssay Description:Displacement of [3H]-(+)-pentazocine from Sigma1-receptor in guinea pig brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
University of Missouri-Columbia

Curated by ChEMBL
LigandPNGBDBM50338985(5-Bromo-N-(4-(5,6-dimethoxyindolin-1-yl)butyl)-2,3...)
Affinity DataKi:  4.52E+3nMAssay Description:Displacement of [3H]-(+)-pentazocine from Sigma1-receptor in guinea pig brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
University of Missouri-Columbia

Curated by ChEMBL
LigandPNGBDBM50338984(5-Bromo-N-(4-(7,8-dimethoxy-4,5-dihydro-1H-benzo[d...)
Affinity DataKi:  5.07E+3nMAssay Description:Displacement of [3H]-(+)-pentazocine from Sigma1-receptor in guinea pig brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed