Compile Data Set for Download or QSAR
Report error Found 36 Enz. Inhib. hit(s) with all data for entry = 50033107
TargetKinesin-like protein KIF11(Human)
Institute For Cancer Research

Curated by ChEMBL
LigandPNGBDBM23780((2R)-2-amino-3-[(naphthalen-2-yldiphenylmethyl)sul...)
Affinity DataIC50: 16.3nMAssay Description:Inhibition of C-terminal His6-tagged human Eg5 microtubule-stimulated ATPase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Institute For Cancer Research

Curated by ChEMBL
LigandPNGBDBM50339678(S-(1,1-Diphenyl[4-iodophenyl]methyl)-L-cysteine | ...)
Affinity DataIC50: 19.3nMAssay Description:Inhibition of C-terminal His6-tagged human Eg5 microtubule-stimulated ATPase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Institute For Cancer Research

Curated by ChEMBL
LigandPNGBDBM50339677(S-(1,1-Diphenyl[4-thiomethylphenyl]methyl)-L-cyste...)
Affinity DataIC50: 21.8nMAssay Description:Inhibition of C-terminal His6-tagged human Eg5 microtubule-stimulated ATPase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Institute For Cancer Research

Curated by ChEMBL
LigandPNGBDBM23821((2R)-2-amino-3-{[(4-bromophenyl)diphenylmethyl]sul...)
Affinity DataIC50: 26.8nMAssay Description:Inhibition of C-terminal His6-tagged human Eg5 microtubule-stimulated ATPase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Institute For Cancer Research

Curated by ChEMBL
LigandPNGBDBM23823((2R)-2-amino-3-{[(4-methoxyphenyl)diphenylmethyl]s...)
Affinity DataIC50: 28.5nMAssay Description:Inhibition of C-terminal His6-tagged human Eg5 microtubule-stimulated ATPase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetKinesin-like protein KIF11(Human)
Institute For Cancer Research

Curated by ChEMBL
LigandPNGBDBM23820((2R)-2-amino-3-{[(4-chlorophenyl)diphenylmethyl]su...)
Affinity DataIC50: 53.3nMAssay Description:Inhibition of C-terminal His6-tagged human Eg5 microtubule-stimulated ATPase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Institute For Cancer Research

Curated by ChEMBL
LigandPNGBDBM50339676(S-(1,1-Diphenyl[4-(ethyl)phenyl]methyl)-L-cysteine...)
Affinity DataIC50: 55.4nMAssay Description:Inhibition of C-terminal His6-tagged human Eg5 microtubule-stimulated ATPase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Institute For Cancer Research

Curated by ChEMBL
LigandPNGBDBM23822((2R)-2-amino-3-{[(4-methylphenyl)diphenylmethyl]su...)
Affinity DataIC50: 61.7nMAssay Description:Inhibition of C-terminal His6-tagged human Eg5 microtubule-stimulated ATPase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Institute For Cancer Research

Curated by ChEMBL
LigandPNGBDBM50339675(S-(1,1-Diphenyl[4-(propyl)phenyl]methyl)-L-cystein...)
Affinity DataIC50: 85.9nMAssay Description:Inhibition of C-terminal His6-tagged human Eg5 microtubule-stimulated ATPase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Institute For Cancer Research

Curated by ChEMBL
LigandPNGBDBM50339673(S-(1,1-Diphenyl[4-(butyl)phenyl]methyl)-L-cysteine...)
Affinity DataIC50: 93.3nMAssay Description:Inhibition of C-terminal His6-tagged human Eg5 microtubule-stimulated ATPase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Institute For Cancer Research

Curated by ChEMBL
LigandPNGBDBM50213730((R)-2-amino-3-(diphenyl(4-(trifluoromethyl)phenyl)...)
Affinity DataIC50: 116nMAssay Description:Inhibition of C-terminal His6-tagged human Eg5 microtubule-stimulated ATPase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Institute For Cancer Research

Curated by ChEMBL
LigandPNGBDBM50339674(S-(1,1-Diphenyl[4-(isopropyl)phenyl]methyl)-L-cyst...)
Affinity DataIC50: 144nMAssay Description:Inhibition of C-terminal His6-tagged human Eg5 microtubule-stimulated ATPase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Institute For Cancer Research

Curated by ChEMBL
LigandPNGBDBM23772(STLC | Tritylcysteine | 3-Tritylthio-L-alanine | N...)
Affinity DataIC50: 285nMAssay Description:Inhibition of C-terminal His6-tagged human Eg5 microtubule-stimulated ATPase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Institute For Cancer Research

Curated by ChEMBL
LigandPNGBDBM50198302((S)-2-amino-3-(tritylthio)propanoic acid | CHEMBL3...)
Affinity DataIC50: 306nMAssay Description:Inhibition of C-terminal His6-tagged human Eg5 microtubule-stimulated ATPase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Institute For Cancer Research

Curated by ChEMBL
LigandPNGBDBM23776((2R)-2-amino-3-[(1,1-diphenylpentyl)sulfanyl]propa...)
Affinity DataIC50: 319nMAssay Description:Inhibition of C-terminal His6-tagged human Eg5 microtubule-stimulated ATPase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Institute For Cancer Research

Curated by ChEMBL
LigandPNGBDBM23802(2-[(triphenylmethyl)sulfanyl]ethan-1-amine | Triph...)
Affinity DataIC50: 396nMAssay Description:Inhibition of C-terminal His6-tagged human Eg5 microtubule-stimulated ATPase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Institute For Cancer Research

Curated by ChEMBL
LigandPNGBDBM50339680(S-(2-Methyl-1,1-diphenylbutyl)-L-cysteine | CHEMBL...)
Affinity DataIC50: 549nMAssay Description:Inhibition of C-terminal His6-tagged human Eg5 microtubule-stimulated ATPase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Institute For Cancer Research

Curated by ChEMBL
LigandPNGBDBM23777((2R)-2-amino-3-[(2-methyl-1,1-diphenylpropyl)sulfa...)
Affinity DataIC50: 1.15E+3nMAssay Description:Inhibition of C-terminal His6-tagged human Eg5 microtubule-stimulated ATPase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Institute For Cancer Research

Curated by ChEMBL
LigandPNGBDBM50339672(S-(1,1-Diphenyl[4-(tert-butyl)phenyl]methyl)-L-cys...)
Affinity DataIC50: 1.24E+3nMAssay Description:Inhibition of C-terminal His6-tagged human Eg5 microtubule-stimulated ATPase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Institute For Cancer Research

Curated by ChEMBL
LigandPNGBDBM50339670(S-(1,1-Diphenyl[4-(cyclohexyl)phenyl]methyl)-L-cys...)
Affinity DataIC50: 1.58E+3nMAssay Description:Inhibition of C-terminal His6-tagged human Eg5 microtubule-stimulated ATPase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Institute For Cancer Research

Curated by ChEMBL
LigandPNGBDBM50339681(S-(2-Ethyl-1,1-diphenylbutyl)-L-cysteine | CHEMBL1...)
Affinity DataIC50: 1.63E+3nMAssay Description:Inhibition of C-terminal His6-tagged human Eg5 microtubule-stimulated ATPase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Institute For Cancer Research

Curated by ChEMBL
LigandPNGBDBM50339671(cid_280618 | CHEMBL1688925 | S-(1,1-Diphenyl[4-bip...)
Affinity DataIC50: 1.97E+3nMAssay Description:Inhibition of C-terminal His6-tagged human Eg5 microtubule-stimulated ATPase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Institute For Cancer Research

Curated by ChEMBL
LigandPNGBDBM50339679(4-((2-amino-2-carboxyethylthio)diphenylmethyl)benz...)
Affinity DataIC50: 1.41E+4nMAssay Description:Inhibition of C-terminal His6-tagged human Eg5 microtubule-stimulated ATPase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Institute For Cancer Research

Curated by ChEMBL
LigandPNGBDBM50339682((R)-2-amino-3-(diphenyl(thiophen-2-yl)methylthio)p...)
Affinity DataIC50: 4.17E+4nMAssay Description:Inhibition of C-terminal His6-tagged human Eg5 microtubule-stimulated ATPase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Institute For Cancer Research

Curated by ChEMBL
LigandPNGBDBM23772(STLC | Tritylcysteine | 3-Tritylthio-L-alanine | N...)
Affinity DataKi:  71.9nMAssay Description:Inhibition of C-terminal His6-tagged human Eg5 basal ATPase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Institute For Cancer Research

Curated by ChEMBL
LigandPNGBDBM50339680(S-(2-Methyl-1,1-diphenylbutyl)-L-cysteine | CHEMBL...)
Affinity DataKi:  76.2nMAssay Description:Inhibition of C-terminal His6-tagged human Eg5 basal ATPase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Institute For Cancer Research

Curated by ChEMBL
LigandPNGBDBM50339673(S-(1,1-Diphenyl[4-(butyl)phenyl]methyl)-L-cysteine...)
Affinity DataKi:  84.2nMAssay Description:Inhibition of C-terminal His6-tagged human Eg5 basal ATPase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Institute For Cancer Research

Curated by ChEMBL
LigandPNGBDBM50198302((S)-2-amino-3-(tritylthio)propanoic acid | CHEMBL3...)
Affinity DataKi:  98.6nMAssay Description:Inhibition of C-terminal His6-tagged human Eg5 basal ATPase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Institute For Cancer Research

Curated by ChEMBL
LigandPNGBDBM23802(2-[(triphenylmethyl)sulfanyl]ethan-1-amine | Triph...)
Affinity DataKi:  156nMAssay Description:Inhibition of C-terminal His6-tagged human Eg5 basal ATPase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Institute For Cancer Research

Curated by ChEMBL
LigandPNGBDBM23777((2R)-2-amino-3-[(2-methyl-1,1-diphenylpropyl)sulfa...)
Affinity DataKi:  175nMAssay Description:Inhibition of C-terminal His6-tagged human Eg5 basal ATPase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Institute For Cancer Research

Curated by ChEMBL
LigandPNGBDBM50339681(S-(2-Ethyl-1,1-diphenylbutyl)-L-cysteine | CHEMBL1...)
Affinity DataKi:  302nMAssay Description:Inhibition of C-terminal His6-tagged human Eg5 basal ATPase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Institute For Cancer Research

Curated by ChEMBL
LigandPNGBDBM50339672(S-(1,1-Diphenyl[4-(tert-butyl)phenyl]methyl)-L-cys...)
Affinity DataKi:  429nMAssay Description:Inhibition of C-terminal His6-tagged human Eg5 basal ATPase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Institute For Cancer Research

Curated by ChEMBL
LigandPNGBDBM50339671(cid_280618 | CHEMBL1688925 | S-(1,1-Diphenyl[4-bip...)
Affinity DataKi:  1.35E+3nMAssay Description:Inhibition of C-terminal His6-tagged human Eg5 basal ATPase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Institute For Cancer Research

Curated by ChEMBL
LigandPNGBDBM50339679(4-((2-amino-2-carboxyethylthio)diphenylmethyl)benz...)
Affinity DataKi:  2.54E+3nMAssay Description:Inhibition of C-terminal His6-tagged human Eg5 basal ATPase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Institute For Cancer Research

Curated by ChEMBL
LigandPNGBDBM50339670(S-(1,1-Diphenyl[4-(cyclohexyl)phenyl]methyl)-L-cys...)
Affinity DataKi:  3.26E+3nMAssay Description:Inhibition of C-terminal His6-tagged human Eg5 basal ATPase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Institute For Cancer Research

Curated by ChEMBL
LigandPNGBDBM50339682((R)-2-amino-3-(diphenyl(thiophen-2-yl)methylthio)p...)
Affinity DataKi:  5.83E+4nMAssay Description:Inhibition of C-terminal His6-tagged human Eg5 basal ATPase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed