Compile Data Set for Download or QSAR
Report error Found 81 Enz. Inhib. hit(s) with all data for entry = 50032993
TargetC-C chemokine receptor type 2(Human)
Incyte

Curated by ChEMBL
LigandPNGBDBM50337608(cis-((1S,3R)-3-(3-ethyl-tetrahydro-2H-pyran-4-ylam...)
Affinity DataIC50: 2.30nMAssay Description:Antagonist activity at human CCR2 in human PBMC assessed as inhibition of MCP1-induced chemotaxis after 30 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Incyte

Curated by ChEMBL
LigandPNGBDBM50337604(Cis-((1S,3R)-1-isopropyl-3-(3-methyl-tetrahydro-2H...)
Affinity DataIC50: 2.5nMAssay Description:Antagonist activity at human CCR2 in human PBMC assessed as inhibition of MCP1-induced chemotaxis after 30 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetC-C chemokine receptor type 2(Mouse)
Incyte

Curated by ChEMBL
LigandPNGBDBM50337619(((1S,3R)-1-isopropyl-3-((3S,4S)-3-methoxytetrahydr...)
Affinity DataIC50: 2.80nMAssay Description:Binding affinity to mouse CCR2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetC-C chemokine receptor type 2(Rat)
Incyte

Curated by ChEMBL
LigandPNGBDBM50337619(((1S,3R)-1-isopropyl-3-((3S,4S)-3-methoxytetrahydr...)
Affinity DataIC50: 2.90nMAssay Description:Binding affinity to rat CCR2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Incyte

Curated by ChEMBL
LigandPNGBDBM50337619(((1S,3R)-1-isopropyl-3-((3S,4S)-3-methoxytetrahydr...)
Affinity DataIC50: 3nMAssay Description:Displacement of [125I]MCP1 from human CCR2 after 30 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Incyte

Curated by ChEMBL
LigandPNGBDBM50337604(Cis-((1S,3R)-1-isopropyl-3-(3-methyl-tetrahydro-2H...)
Affinity DataIC50: 3.10nMAssay Description:Displacement of [125I]MCP1 from human CCR2 after 30 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Incyte

Curated by ChEMBL
LigandPNGBDBM50337619(((1S,3R)-1-isopropyl-3-((3S,4S)-3-methoxytetrahydr...)
Affinity DataIC50: 3.20nMAssay Description:Antagonist activity at human CCR2 in human PBMC assessed as inhibition of MCP1-induced chemotaxis after 30 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Incyte

Curated by ChEMBL
LigandPNGBDBM50337634(((1S,3R)-3-((3S,4S)-3-methoxy-tetrahydro-2H-pyran-...)
Affinity DataIC50: 3.20nMAssay Description:Displacement of MCP-Alexa 488 from CCR2 in human whole blood after 5 mins by flow cytometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Incyte

Curated by ChEMBL
LigandPNGBDBM50337634(((1S,3R)-3-((3S,4S)-3-methoxy-tetrahydro-2H-pyran-...)
Affinity DataIC50: 3.40nMAssay Description:Displacement of [125I]MCP1 from human CCR2 after 30 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Incyte

Curated by ChEMBL
LigandPNGBDBM50337619(((1S,3R)-1-isopropyl-3-((3S,4S)-3-methoxytetrahydr...)
Affinity DataIC50: 3.90nMAssay Description:Displacement of MCP-Alexa 488 from CCR2 in human whole blood after 5 mins by flow cytometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Incyte

Curated by ChEMBL
LigandPNGBDBM50337619(((1S,3R)-1-isopropyl-3-((3S,4S)-3-methoxytetrahydr...)
Affinity DataIC50: 4.30nMAssay Description:Displacement of labeled MIP-1beta from human CCR5 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Incyte

Curated by ChEMBL
LigandPNGBDBM50337608(cis-((1S,3R)-3-(3-ethyl-tetrahydro-2H-pyran-4-ylam...)
Affinity DataIC50: 4.60nMAssay Description:Displacement of [125I]MCP1 from human CCR2 after 30 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Incyte

Curated by ChEMBL
LigandPNGBDBM50337619(((1S,3R)-1-isopropyl-3-((3S,4S)-3-methoxytetrahydr...)
Affinity DataIC50: 5.30nMAssay Description:Displacement of labeled MIP-1beta from human CCR5 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Incyte

Curated by ChEMBL
LigandPNGBDBM50337612(cis-((1S,3R)-1-isopropyl-3-((3S,4S)-3-methoxy-tetr...)
Affinity DataIC50: 5.70nMAssay Description:Displacement of [125I]MCP1 from human CCR2 after 30 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Incyte

Curated by ChEMBL
LigandPNGBDBM50337605(Cis-((1S,3R)-1-isopropyl-3-(3-methyl-tetrahydro-2H...)
Affinity DataIC50: 5.70nMAssay Description:Antagonist activity at human CCR2 in human PBMC assessed as inhibition of MCP1-induced chemotaxis after 30 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Incyte

Curated by ChEMBL
LigandPNGBDBM50337618(((1S,3R)-1-isopropyl-3-((3S,4S)-3-methoxy-tetrahyd...)
Affinity DataIC50: 6.20nMAssay Description:Antagonist activity at human CCR2 in human PBMC assessed as inhibition of MCP1-induced chemotaxis after 30 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Incyte

Curated by ChEMBL
LigandPNGBDBM50337618(((1S,3R)-1-isopropyl-3-((3S,4S)-3-methoxy-tetrahyd...)
Affinity DataIC50: 6.20nMAssay Description:Displacement of [125I]MCP1 from human CCR2 after 30 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Incyte

Curated by ChEMBL
LigandPNGBDBM50337612(cis-((1S,3R)-1-isopropyl-3-((3S,4S)-3-methoxy-tetr...)
Affinity DataIC50: 6.90nMAssay Description:Antagonist activity at human CCR2 in human PBMC assessed as inhibition of MCP1-induced chemotaxis after 30 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Incyte

Curated by ChEMBL
LigandPNGBDBM50337612(cis-((1S,3R)-1-isopropyl-3-((3S,4S)-3-methoxy-tetr...)
Affinity DataIC50: 7nMAssay Description:Displacement of MCP-Alexa 488 from CCR2 in human whole blood after 5 mins by flow cytometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Incyte

Curated by ChEMBL
LigandPNGBDBM50337634(((1S,3R)-3-((3S,4S)-3-methoxy-tetrahydro-2H-pyran-...)
Affinity DataIC50: 8.40nMAssay Description:Displacement of labeled MIP-1beta from human CCR5 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Incyte

Curated by ChEMBL
LigandPNGBDBM50337620(((1S,3R)-1-isopropyl-3-((3S,4S)-3-methoxy-tetrahyd...)
Affinity DataIC50: 8.90nMAssay Description:Antagonist activity at human CCR2 in human PBMC assessed as inhibition of MCP1-induced chemotaxis after 30 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Incyte

Curated by ChEMBL
LigandPNGBDBM50337634(((1S,3R)-3-((3S,4S)-3-methoxy-tetrahydro-2H-pyran-...)
Affinity DataIC50: 9nMAssay Description:Antagonist activity at human CCR2 in human PBMC assessed as inhibition of MCP1-induced chemotaxis after 30 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Incyte

Curated by ChEMBL
LigandPNGBDBM50337622(((1S,3R)-1-ethyl-3-((3S,4S)-3-methoxy-tetrahydro-2...)
Affinity DataIC50: 9.30nMAssay Description:Displacement of [125I]MCP1 from human CCR2 after 30 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Incyte

Curated by ChEMBL
LigandPNGBDBM50337634(((1S,3R)-3-((3S,4S)-3-methoxy-tetrahydro-2H-pyran-...)
Affinity DataIC50: 11nMAssay Description:Antagonist activity at human CCR5 receptor by chemotaxis assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Incyte

Curated by ChEMBL
LigandPNGBDBM50337620(((1S,3R)-1-isopropyl-3-((3S,4S)-3-methoxy-tetrahyd...)
Affinity DataIC50: 11nMAssay Description:Displacement of [125I]MCP1 from human CCR2 after 30 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Incyte

Curated by ChEMBL
LigandPNGBDBM50337623(((1S,3R)-3-((3S,4S)-3-methoxy-tetrahydro-2H-pyran-...)
Affinity DataIC50: 11nMAssay Description:Displacement of [125I]MCP1 from human CCR2 after 30 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Incyte

Curated by ChEMBL
LigandPNGBDBM50337605(Cis-((1S,3R)-1-isopropyl-3-(3-methyl-tetrahydro-2H...)
Affinity DataIC50: 11nMAssay Description:Displacement of [125I]MCP1 from human CCR2 after 30 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Incyte

Curated by ChEMBL
LigandPNGBDBM50337609(cis-((1S,3R)-3-(3-ethyl-tetrahydro-2H-pyran-4-ylam...)
Affinity DataIC50: 12nMAssay Description:Displacement of [125I]MCP1 from human CCR2 after 30 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Incyte

Curated by ChEMBL
LigandPNGBDBM50337633(((1S,3R)-3-((3S,4S)-3-methoxy-tetrahydro-2H-pyran-...)
Affinity DataIC50: 14nMAssay Description:Displacement of [125I]MCP1 from human CCR2 after 30 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Incyte

Curated by ChEMBL
LigandPNGBDBM50337613(cis-((1S,3R)-1-isopropyl-3-(3-methoxy-tetrahydro-2...)
Affinity DataIC50: 15nMAssay Description:Displacement of [125I]MCP1 from human CCR2 after 30 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Incyte

Curated by ChEMBL
LigandPNGBDBM50337633(((1S,3R)-3-((3S,4S)-3-methoxy-tetrahydro-2H-pyran-...)
Affinity DataIC50: 17nMAssay Description:Displacement of [125I]MCP1 from human CCR2 after 30 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Incyte

Curated by ChEMBL
LigandPNGBDBM50337620(((1S,3R)-1-isopropyl-3-((3S,4S)-3-methoxy-tetrahyd...)
Affinity DataIC50: 17nMAssay Description:Displacement of MCP-Alexa 488 from CCR2 in human whole blood after 5 mins by flow cytometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Incyte

Curated by ChEMBL
LigandPNGBDBM50337608(cis-((1S,3R)-3-(3-ethyl-tetrahydro-2H-pyran-4-ylam...)
Affinity DataIC50: 18nMAssay Description:Displacement of labeled MIP-1beta from human CCR5 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Incyte

Curated by ChEMBL
LigandPNGBDBM50337602(((1S,3R)-1-isopropyl-3-(tetrahydro-2H-pyran-4-ylam...)
Affinity DataIC50: 18nMAssay Description:Displacement of [125I]MCP1 from human CCR2 after 30 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Incyte

Curated by ChEMBL
LigandPNGBDBM50337632(((1R,3R)-1-(3-fluoropropyl)-3-((3S,4S)-3-methoxy-t...)
Affinity DataIC50: 19nMAssay Description:Displacement of [125I]MCP1 from human CCR2 after 30 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Incyte

Curated by ChEMBL
LigandPNGBDBM50337626(((1S,3R)-3-((3S,4S)-3-methoxy-tetrahydro-2H-pyran-...)
Affinity DataIC50: 20nMAssay Description:Displacement of [125I]MCP1 from human CCR2 after 30 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Incyte

Curated by ChEMBL
LigandPNGBDBM50337624(((1S,3R)-1-sec-butyl-3-((3S,4S)-3-methoxy-tetrahyd...)
Affinity DataIC50: 23nMAssay Description:Displacement of [125I]MCP1 from human CCR2 after 30 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Incyte

Curated by ChEMBL
LigandPNGBDBM50337614(cis-((1S,3R)-3-(3-ethoxy-tetrahydro-2H-pyran-4-yla...)
Affinity DataIC50: 23nMAssay Description:Displacement of labeled MIP-1beta from human CCR5 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Incyte

Curated by ChEMBL
LigandPNGBDBM50337612(cis-((1S,3R)-1-isopropyl-3-((3S,4S)-3-methoxy-tetr...)
Affinity DataIC50: 23nMAssay Description:Displacement of labeled MIP-1beta from human CCR5 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Incyte

Curated by ChEMBL
LigandPNGBDBM50337618(((1S,3R)-1-isopropyl-3-((3S,4S)-3-methoxy-tetrahyd...)
Affinity DataIC50: 27nMAssay Description:Displacement of labeled MIP-1beta from human CCR5 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Incyte

Curated by ChEMBL
LigandPNGBDBM50337606(trans-((1S,3R)-1-isopropyl-3-(3-methyl-tetrahydro-...)
Affinity DataIC50: 28nMAssay Description:Displacement of [125I]MCP1 from human CCR2 after 30 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Incyte

Curated by ChEMBL
LigandPNGBDBM50337625(((1R,3R)-1-(cyclopropylmethyl)-3-((3S,4S)-3-methox...)
Affinity DataIC50: 28nMAssay Description:Displacement of [125I]MCP1 from human CCR2 after 30 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Incyte

Curated by ChEMBL
LigandPNGBDBM50337622(((1S,3R)-1-ethyl-3-((3S,4S)-3-methoxy-tetrahydro-2...)
Affinity DataIC50: 32nMAssay Description:Displacement of [125I]MCP1 from human CCR2 after 30 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Incyte

Curated by ChEMBL
LigandPNGBDBM50337627(((1S,3R)-1-(ethoxymethyl)-3-((3S,4S)-3-methoxy-tet...)
Affinity DataIC50: 34nMAssay Description:Displacement of [125I]MCP1 from human CCR2 after 30 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Incyte

Curated by ChEMBL
LigandPNGBDBM50337620(((1S,3R)-1-isopropyl-3-((3S,4S)-3-methoxy-tetrahyd...)
Affinity DataIC50: 35nMAssay Description:Displacement of labeled MIP-1beta from human CCR5 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Incyte

Curated by ChEMBL
LigandPNGBDBM50337616(cis-((1S,3R)-1-isopropyl-3-(3-(methoxymethyl)-tetr...)
Affinity DataIC50: 36nMAssay Description:Displacement of [125I]MCP1 from human CCR2 after 30 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Incyte

Curated by ChEMBL
LigandPNGBDBM50337632(((1R,3R)-1-(3-fluoropropyl)-3-((3S,4S)-3-methoxy-t...)
Affinity DataIC50: 40nMAssay Description:Displacement of [125I]MCP1 from human CCR2 after 30 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Incyte

Curated by ChEMBL
LigandPNGBDBM50337623(((1S,3R)-3-((3S,4S)-3-methoxy-tetrahydro-2H-pyran-...)
Affinity DataIC50: 41nMAssay Description:Displacement of [125I]MCP1 from human CCR2 after 30 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Incyte

Curated by ChEMBL
LigandPNGBDBM50337614(cis-((1S,3R)-3-(3-ethoxy-tetrahydro-2H-pyran-4-yla...)
Affinity DataIC50: 46nMAssay Description:Displacement of [125I]MCP1 from human CCR2 after 30 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Incyte

Curated by ChEMBL
LigandPNGBDBM50337610(trans-((1S,3R)-3-(3-ethyl-tetrahydro-2H-pyran-4-yl...)
Affinity DataIC50: 46nMAssay Description:Displacement of [125I]MCP1 from human CCR2 after 30 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Displayed 1 to 50 (of 81 total ) | Next | Last >>
Jump to: