Compile Data Set for Download or QSAR
Report error Found 15 Enz. Inhib. hit(s) with all data for entry = 50033275
Target6-phosphogluconate dehydrogenase, decarboxylating(Trypanosoma brucei brucei (strain 927/4 GUTat10.1))
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50342610((2R,3R,4S)-2,3,4-trihydroxy-5-(hydroxyamino)-5-oxo...)
Affinity DataIC50: 5.80E+3nMAssay Description:Inhibition of Trypanosoma brucei 6-phosphogluconate dehydrogenaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetArabinose 5-phosphate isomerase KdsD(Francisella tularensis subsp. tularensis (strain S...)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50148765(Acetic acid (1R,3R)-2-acetoxy-1-hydroxycarbamoyl-3...)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of Francisella tularensis N-terminal hexahistidine-tagged arabinose phosphate isomerase expressed in Escherichia coli BL21(DE3) after 3 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetArabinose 5-phosphate isomerase KdsD(Francisella tularensis subsp. tularensis (strain S...)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50148769((R)-Phosphoric acid mono-((R)-3-carbamoyl-2,3-dihy...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Francisella tularensis N-terminal hexahistidine-tagged arabinose phosphate isomerase expressed in Escherichia coli BL21(DE3) after 3 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetArabinose 5-phosphate isomerase KdsD(Francisella tularensis subsp. tularensis (strain S...)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50148767(Phosphoric acid mono-((1R,3R)-2,3-dihydroxy-3-hydr...)
Affinity DataIC50: 3.50E+4nMAssay Description:Inhibition of Francisella tularensis N-terminal hexahistidine-tagged arabinose phosphate isomerase expressed in Escherichia coli BL21(DE3) after 3 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetArabinose 5-phosphate isomerase KdsD(Francisella tularensis subsp. tularensis (strain S...)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50148780((5-(hydroxycarbamoyl)-2,2-dimethyl-1,3-dioxolan-4-...)
Affinity DataIC50: 3.00E+6nMAssay Description:Inhibition of Francisella tularensis N-terminal hexahistidine-tagged arabinose phosphate isomerase expressed in Escherichia coli BL21(DE3) after 3 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
Target6-phosphogluconate dehydrogenase, decarboxylating(Trypanosoma brucei brucei (strain 927/4 GUTat10.1))
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50148767(Phosphoric acid mono-((1R,3R)-2,3-dihydroxy-3-hydr...)
Affinity DataKi:  10nMAssay Description:Inhibition of Trypanosoma brucei 6-phosphogluconate dehydrogenaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
Target6-phosphogluconate dehydrogenase, decarboxylating(Trypanosoma brucei brucei (strain 927/4 GUTat10.1))
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50148780((5-(hydroxycarbamoyl)-2,2-dimethyl-1,3-dioxolan-4-...)
Affinity DataKi:  35nMAssay Description:Inhibition of Trypanosoma brucei 6-phosphogluconate dehydrogenaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
Target6-phosphogluconate dehydrogenase, decarboxylating(Trypanosoma brucei brucei (strain 927/4 GUTat10.1))
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50148765(Acetic acid (1R,3R)-2-acetoxy-1-hydroxycarbamoyl-3...)
Affinity DataKi:  80nMAssay Description:Inhibition of Trypanosoma brucei 6-phosphogluconate dehydrogenaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetGlucose-6-phosphate isomerase(Rabbit)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50342610((2R,3R,4S)-2,3,4-trihydroxy-5-(hydroxyamino)-5-oxo...)
Affinity DataKi:  100nMAssay Description:Inhibition of rabbit cytosolic phosphoglucose isomeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
Target6-phosphogluconate dehydrogenase, decarboxylating(Sheep)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50148765(Acetic acid (1R,3R)-2-acetoxy-1-hydroxycarbamoyl-3...)
Affinity DataKi:  360nMAssay Description:Inhibition of sheep 6-phosphogluconate dehydrogenaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
Target6-phosphogluconate dehydrogenase, decarboxylating(Trypanosoma brucei brucei (strain 927/4 GUTat10.1))
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50148769((R)-Phosphoric acid mono-((R)-3-carbamoyl-2,3-dihy...)
Affinity DataKi:  1.52E+3nMAssay Description:Inhibition of Trypanosoma brucei 6-phosphogluconate dehydrogenaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetTriosephosphate isomerase(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50167777(2-(hydroxyamino)-2-oxoethyl dihydrogen phosphate |...)
Affinity DataKi:  4.00E+3nMAssay Description:Inhibition of Triosephosphate isomeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetRibose-5-phosphate isomerase B(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50148767(Phosphoric acid mono-((1R,3R)-2,3-dihydroxy-3-hydr...)
Affinity DataKi:  4.00E+5nMAssay Description:Inhibition of Mycobacterium tuberculosis rpiBMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetRibose-5-phosphate isomerase B(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50148767(Phosphoric acid mono-((1R,3R)-2,3-dihydroxy-3-hydr...)
Affinity DataKi:  4.00E+5nMAssay Description:Inhibition of Mycobacterium tuberculosis rpiBMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetRibose-5-phosphate isomerase B(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50148769((R)-Phosphoric acid mono-((R)-3-carbamoyl-2,3-dihy...)
Affinity DataKi: >3.00E+7nMAssay Description:Inhibition of Mycobacterium tuberculosis rpiBMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed