Compile Data Set for Download or QSAR
Report error Found 13 Enz. Inhib. hit(s) with all data for entry = 50033273
TargetAcetylcholinesterase(Human)
Alchemical Research

Curated by ChEMBL
LigandPNGBDBM50089619(9-(3,4-Dimethoxy-phenyl)-4a,12a-dihydroxy-4,4,6a,1...)
Affinity DataIC50: 1nMAssay Description:Inhibition of AChE-induced amyloid beta aggregationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Human)
Alchemical Research

Curated by ChEMBL
LigandPNGBDBM50342601(Huperzine A | CHEMBL1255901)
Affinity DataIC50: 5nMAssay Description:Inhibition of AChE-induced amyloid beta aggregationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Human)
Alchemical Research

Curated by ChEMBL
LigandPNGBDBM8960(2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2...)
Affinity DataIC50: 6nMAssay Description:Inhibition of AChE-induced amyloid beta aggregationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetAcetylcholinesterase(Human)
Alchemical Research

Curated by ChEMBL
LigandPNGBDBM50089616(CHEMBL24686 | territrem B | 4a,12a-Dihydroxy-4,4,6...)
Affinity DataIC50: 6nMAssay Description:Inhibition of AChE-induced amyloid beta aggregationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetCholinesterase(Human)
Alchemical Research

Curated by ChEMBL
LigandPNGBDBM8961(CHEMBL95 | Cognex | cid_1935 | CHEMBL1337960 | 1,2...)
Affinity DataIC50: 12nMAssay Description:Inhibition of BChEMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetCholinesterase(Human)
Alchemical Research

Curated by ChEMBL
LigandPNGBDBM10620(3-[(1S)-1-(dimethylamino)ethyl]phenyl N-ethyl-N-me...)
Affinity DataIC50: 49nMAssay Description:Inhibition of BChEMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Human)
Alchemical Research

Curated by ChEMBL
LigandPNGBDBM10620(3-[(1S)-1-(dimethylamino)ethyl]phenyl N-ethyl-N-me...)
Affinity DataIC50: 54nMAssay Description:Inhibition of AChE-induced amyloid beta aggregationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCholinesterase(Human)
Alchemical Research

Curated by ChEMBL
LigandPNGBDBM50342601(Huperzine A | CHEMBL1255901)
Affinity DataIC50: 100nMAssay Description:Inhibition of BChEMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Human)
Alchemical Research

Curated by ChEMBL
LigandPNGBDBM8961(CHEMBL95 | Cognex | cid_1935 | CHEMBL1337960 | 1,2...)
Affinity DataIC50: 200nMAssay Description:Inhibition of AChE-induced amyloid beta aggregationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetAcetylcholinesterase(Human)
Alchemical Research

Curated by ChEMBL
LigandPNGBDBM10404(galantamine | (1S,12S,14R)-9-methoxy-4-methyl-11-o...)
Affinity DataIC50: 350nMAssay Description:Inhibition of AChE-induced amyloid beta aggregationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCholinesterase(Human)
Alchemical Research

Curated by ChEMBL
LigandPNGBDBM8960(2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2...)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of BChEMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCholinesterase(Human)
Alchemical Research

Curated by ChEMBL
LigandPNGBDBM50089619(9-(3,4-Dimethoxy-phenyl)-4a,12a-dihydroxy-4,4,6a,1...)
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of BChEMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCholinesterase(Human)
Alchemical Research

Curated by ChEMBL
LigandPNGBDBM10404(galantamine | (1S,12S,14R)-9-methoxy-4-methyl-11-o...)
Affinity DataIC50: 1.86E+4nMAssay Description:Inhibition of BChEMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed