Compile Data Set for Download or QSAR
Report error Found 21 Enz. Inhib. hit(s) with all data for entry = 50032727
TargetPeroxisome proliferator-activated receptor gamma(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50333777((E)-2-(2-Methyl-4-(1-(((5-methyl-2-phenyloxazol-4-...)
Affinity DataEC50:  300nMAssay Description:Agonist activity at human PPARgamma expressed in HepG2 cells co-transfected with PPRE3-TK-luc assessed as beta-galactosidase activity after 20 to 22 ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM28701(Cedur | 2-(4-{2-[(4-chlorophenyl)formamido]ethyl}p...)
Affinity DataEC50:  1.89E+4nMAssay Description:Agonist activity at human PPARdelta expressed in HepG2 cells co-transfected with PPRE3-TK-luc assessed as beta-galactosidase activity after 20 to 22 ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetPeroxisome proliferator-activated receptor delta(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM28661(GW501516 | CHEMBL38943 | 2-{2-methyl-4-[({4-methyl...)
Affinity DataEC50:  1.20nMAssay Description:Agonist activity at human PPARdelta expressed in HepG2 cells co-transfected with PPRE3-TK-luc assessed as beta-galactosidase activity after 20 to 22 ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50333778((E)-2-(2-Methyl-4-(1-(((5-methyl-2-(p-tolyl)oxazol...)
Affinity DataEC50:  300nMAssay Description:Agonist activity at human PPARdelta expressed in HepG2 cells co-transfected with PPRE3-TK-luc assessed as beta-galactosidase activity after 20 to 22 ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50333777((E)-2-(2-Methyl-4-(1-(((5-methyl-2-phenyloxazol-4-...)
Affinity DataEC50:  800nMAssay Description:Agonist activity at human PPARdelta expressed in HepG2 cells co-transfected with PPRE3-TK-luc assessed as beta-galactosidase activity after 20 to 22 ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50333776((E)-2-(4-(Cyclohexyl(((4-methyl-2-(4-(trifluoromet...)
Affinity DataEC50:  700nMAssay Description:Agonist activity at human PPARdelta expressed in HepG2 cells co-transfected with PPRE3-TK-luc assessed as beta-galactosidase activity after 20 to 22 ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50333775((E)-2-(2-methyl-4-(1-(((4-methyl-2-(4-(trifluorome...)
Affinity DataEC50:  800nMAssay Description:Agonist activity at human PPARdelta expressed in HepG2 cells co-transfected with PPRE3-TK-luc assessed as beta-galactosidase activity after 20 to 22 ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50333774((E)-(2-Methyl-4-{1-[4-methyl-2-(4-trifluoromethylp...)
Affinity DataEC50:  10nMAssay Description:Agonist activity at human PPARdelta expressed in HepG2 cells co-transfected with PPRE3-TK-luc assessed as beta-galactosidase activity after 20 to 22 ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM28701(Cedur | 2-(4-{2-[(4-chlorophenyl)formamido]ethyl}p...)
Affinity DataEC50:  5.72E+4nMAssay Description:Agonist activity at human PPARgamma expressed in HepG2 cells co-transfected with PPRE3-TK-luc assessed as beta-galactosidase activity after 20 to 22 ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetPeroxisome proliferator-activated receptor gamma(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM28661(GW501516 | CHEMBL38943 | 2-{2-methyl-4-[({4-methyl...)
Affinity DataEC50:  800nMAssay Description:Agonist activity at human PPARgamma expressed in HepG2 cells co-transfected with PPRE3-TK-luc assessed as beta-galactosidase activity after 20 to 22 ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50333778((E)-2-(2-Methyl-4-(1-(((5-methyl-2-(p-tolyl)oxazol...)
Affinity DataEC50:  400nMAssay Description:Agonist activity at human PPARgamma expressed in HepG2 cells co-transfected with PPRE3-TK-luc assessed as beta-galactosidase activity after 20 to 22 ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50333774((E)-(2-Methyl-4-{1-[4-methyl-2-(4-trifluoromethylp...)
Affinity DataEC50:  8nMAssay Description:Agonist activity at human PPARalpha expressed in HepG2 cells co-transfected with PPRE3-TK-luc assessed as beta-galactosidase activity after 20 to 22 ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50333776((E)-2-(4-(Cyclohexyl(((4-methyl-2-(4-(trifluoromet...)
Affinity DataEC50:  1.00E+3nMAssay Description:Agonist activity at human PPARgamma expressed in HepG2 cells co-transfected with PPRE3-TK-luc assessed as beta-galactosidase activity after 20 to 22 ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50333775((E)-2-(2-methyl-4-(1-(((4-methyl-2-(4-(trifluorome...)
Affinity DataEC50:  800nMAssay Description:Agonist activity at human PPARgamma expressed in HepG2 cells co-transfected with PPRE3-TK-luc assessed as beta-galactosidase activity after 20 to 22 ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50333774((E)-(2-Methyl-4-{1-[4-methyl-2-(4-trifluoromethylp...)
Affinity DataEC50:  6nMAssay Description:Agonist activity at human PPARgamma expressed in HepG2 cells co-transfected with PPRE3-TK-luc assessed as beta-galactosidase activity after 20 to 22 ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM28701(Cedur | 2-(4-{2-[(4-chlorophenyl)formamido]ethyl}p...)
Affinity DataEC50:  4.25E+4nMAssay Description:Agonist activity at human PPARalpha expressed in HepG2 cells co-transfected with PPRE3-TK-luc assessed as beta-galactosidase activity after 20 to 22 ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetPeroxisome proliferator-activated receptor alpha(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM28661(GW501516 | CHEMBL38943 | 2-{2-methyl-4-[({4-methyl...)
Affinity DataEC50:  1.10E+3nMAssay Description:Agonist activity at human PPARalpha expressed in HepG2 cells co-transfected with PPRE3-TK-luc assessed as beta-galactosidase activity after 20 to 22 ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50333778((E)-2-(2-Methyl-4-(1-(((5-methyl-2-(p-tolyl)oxazol...)
Affinity DataEC50:  150nMAssay Description:Agonist activity at human PPARalpha expressed in HepG2 cells co-transfected with PPRE3-TK-luc assessed as beta-galactosidase activity after 20 to 22 ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50333777((E)-2-(2-Methyl-4-(1-(((5-methyl-2-phenyloxazol-4-...)
Affinity DataEC50:  500nMAssay Description:Agonist activity at human PPARalpha expressed in HepG2 cells co-transfected with PPRE3-TK-luc assessed as beta-galactosidase activity after 20 to 22 ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50333776((E)-2-(4-(Cyclohexyl(((4-methyl-2-(4-(trifluoromet...)
Affinity DataEC50:  1.60E+3nMAssay Description:Agonist activity at human PPARalpha expressed in HepG2 cells co-transfected with PPRE3-TK-luc assessed as beta-galactosidase activity after 20 to 22 ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50333775((E)-2-(2-methyl-4-(1-(((4-methyl-2-(4-(trifluorome...)
Affinity DataEC50:  120nMAssay Description:Agonist activity at human PPARalpha expressed in HepG2 cells co-transfected with PPRE3-TK-luc assessed as beta-galactosidase activity after 20 to 22 ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed