Compile Data Set for Download or QSAR
Report error Found 40 Enz. Inhib. hit(s) with all data for entry = 50032876
TargetProstaglandin G/H synthase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50336012(6-chloro-8-(4-chlorophenyl)-2-(trifluoromethyl)-2H...)
Affinity DataIC50: 21nMAssay Description:Inhibition of human COX2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM11639(Celecoxib | CLX | Celebrex | 4-[5-(4-methylphenyl)...)
Affinity DataIC50: 40nMAssay Description:Inhibition of human COX2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50336018(6-chloro-8-(3-fluoro-4-methylphenyl)-2-(trifluorom...)
Affinity DataIC50: 66nMAssay Description:Inhibition of human COX2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50336014(6-chloro-8-(4-ethylphenyl)-2-(trifluoromethyl)-2H-...)
Affinity DataIC50: 78nMAssay Description:Inhibition of human COX2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50336013(6-chloro-8-p-tolyl-2-(trifluoromethyl)-2H-chromene...)
Affinity DataIC50: 103nMAssay Description:Inhibition of human COX2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50331883(6-chloro-8-phenyl-2-(trifluoromethyl)-2H-chromene-...)
Affinity DataIC50: 188nMAssay Description:Inhibition of human COX2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50336016(6-chloro-8-(4-(ethylthio)phenyl)-2-(trifluoromethy...)
Affinity DataIC50: 242nMAssay Description:Inhibition of human COX2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50336012(6-chloro-8-(4-chlorophenyl)-2-(trifluoromethyl)-2H...)
Affinity DataIC50: 242nMAssay Description:Inhibition of human COX1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50331875(6,8-dichloro-2-(trifluoromethyl)-2H-chromene-3-car...)
Affinity DataIC50: 300nMAssay Description:Inhibition of COX2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50331875(6,8-dichloro-2-(trifluoromethyl)-2H-chromene-3-car...)
Affinity DataIC50: 300nMAssay Description:Inhibition of human COX2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50336019(6-chloro-8-(4-methoxy-3-methylphenyl)-2-(trifluoro...)
Affinity DataIC50: 339nMAssay Description:Inhibition of human COX2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50336015(6-chloro-8-(4-ethoxyphenyl)-2-(trifluoromethyl)-2H...)
Affinity DataIC50: 355nMAssay Description:Inhibition of human COX2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50336011(6-chloro-8-(4-fluorophenyl)-2-(trifluoromethyl)-2H...)
Affinity DataIC50: 740nMAssay Description:Inhibition of human COX1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50331885(6-chloro-8-(4-sulfamoylphenyl)-2-(trifluoromethyl)...)
Affinity DataIC50: 758nMAssay Description:Inhibition of human COX2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50336006(8-(4-aminophenyl)-6-chloro-2-(trifluoromethyl)-2H-...)
Affinity DataIC50: 1.39E+3nMAssay Description:Inhibition of human COX1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50331883(6-chloro-8-phenyl-2-(trifluoromethyl)-2H-chromene-...)
Affinity DataIC50: 1.54E+3nMAssay Description:Inhibition of human COX1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50336006(8-(4-aminophenyl)-6-chloro-2-(trifluoromethyl)-2H-...)
Affinity DataIC50: 1.82E+3nMAssay Description:Inhibition of human COX2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50336008(6-chloro-8-(4-(hydroxymethyl)phenyl)-2-(trifluorom...)
Affinity DataIC50: 2.44E+3nMAssay Description:Inhibition of human COX1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50336009(6-chloro-8-(4-hydroxyphenyl)-2-(trifluoromethyl)-2...)
Affinity DataIC50: 2.91E+3nMAssay Description:Inhibition of human COX1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50336009(6-chloro-8-(4-hydroxyphenyl)-2-(trifluoromethyl)-2...)
Affinity DataIC50: 3.48E+3nMAssay Description:Inhibition of human COX2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50336005(6-chloro-8-(4-(methylsulfonyl)phenyl)-2-(trifluoro...)
Affinity DataIC50: 3.87E+3nMAssay Description:Inhibition of human COX1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50336013(6-chloro-8-p-tolyl-2-(trifluoromethyl)-2H-chromene...)
Affinity DataIC50: 4.34E+3nMAssay Description:Inhibition of human COX1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50336008(6-chloro-8-(4-(hydroxymethyl)phenyl)-2-(trifluorom...)
Affinity DataIC50: 6.38E+3nMAssay Description:Inhibition of human COX2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50336017(6-chloro-8-(4-isobutylphenyl)-2-(trifluoromethyl)-...)
Affinity DataIC50: 1.34E+4nMAssay Description:Inhibition of human COX2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM11639(Celecoxib | CLX | Celebrex | 4-[5-(4-methylphenyl)...)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of human COX1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50336014(6-chloro-8-(4-ethylphenyl)-2-(trifluoromethyl)-2H-...)
Affinity DataIC50: 1.77E+4nMAssay Description:Inhibition of human COX1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50336005(6-chloro-8-(4-(methylsulfonyl)phenyl)-2-(trifluoro...)
Affinity DataIC50: 2.13E+4nMAssay Description:Inhibition of human COX2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50336018(6-chloro-8-(3-fluoro-4-methylphenyl)-2-(trifluorom...)
Affinity DataIC50: 2.47E+4nMAssay Description:Inhibition of human COX1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50336017(6-chloro-8-(4-isobutylphenyl)-2-(trifluoromethyl)-...)
Affinity DataIC50: 2.65E+4nMAssay Description:Inhibition of human COX1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50331875(6,8-dichloro-2-(trifluoromethyl)-2H-chromene-3-car...)
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibition of human COX1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50336015(6-chloro-8-(4-ethoxyphenyl)-2-(trifluoromethyl)-2H...)
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibition of human COX1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50331875(6,8-dichloro-2-(trifluoromethyl)-2H-chromene-3-car...)
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibition of COX1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50336007(6-chloro-8-(4-(methylsulfonamido)phenyl)-2-(triflu...)
Affinity DataIC50: 4.01E+4nMAssay Description:Inhibition of human COX2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50336016(6-chloro-8-(4-(ethylthio)phenyl)-2-(trifluoromethy...)
Affinity DataIC50: 7.59E+4nMAssay Description:Inhibition of human COX1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50331885(6-chloro-8-(4-sulfamoylphenyl)-2-(trifluoromethyl)...)
Affinity DataIC50: 9.14E+4nMAssay Description:Inhibition of human COX1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50336010(8-(4-carboxyphenyl)-6-chloro-2-(trifluoromethyl)-2...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human COX1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50336011(6-chloro-8-(4-fluorophenyl)-2-(trifluoromethyl)-2H...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human COX2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50336010(8-(4-carboxyphenyl)-6-chloro-2-(trifluoromethyl)-2...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human COX2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50336019(6-chloro-8-(4-methoxy-3-methylphenyl)-2-(trifluoro...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human COX1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50336007(6-chloro-8-(4-(methylsulfonamido)phenyl)-2-(triflu...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human COX1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed