Compile Data Set for Download or QSAR
Report error Found 26 Enz. Inhib. hit(s) with all data for entry = 50039337
TargetC-C chemokine receptor type 5(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50334975(endo-methyl 3-(8-((S)-3-acetamido-3-(3-fluoropheny...)
Affinity DataIC50: 0.100nMAssay Description:Antagonist activity at CCR5 receptor expressed in HeLa-P4 cells co-expressing CD4 assessed as inhibition of infusion to HIV gp120 expressed in CHO-ta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50334986(4,4-Difluoro-cyclohexanecarboxylic acid {(S)-3-[(1...)
Affinity DataIC50: 0.200nMAssay Description:Antagonist activity at CCR5 receptor expressed in HeLa-P4 cells co-expressing CD4 assessed as inhibition of infusion to HIV gp120 expressed in CHO-ta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50334974(endo-methyl 3-(8-((S)-3-(3-fluorophenyl)-3-(methox...)
Affinity DataIC50: 0.200nMAssay Description:Antagonist activity at CCR5 receptor expressed in HeLa-P4 cells co-expressing CD4 assessed as inhibition of infusion to HIV gp120 expressed in CHO-ta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50334973(endo-methyl(S)-3-(3-(5-acetyl-2-methyl-4,5,6,7-tet...)
Affinity DataIC50: 0.200nMAssay Description:Antagonist activity at CCR5 receptor expressed in HeLa-P4 cells co-expressing CD4 assessed as inhibition of infusion to HIV gp120 expressed in CHO-ta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50334978(endo-methyl 3-(8-((S)-3-acetamido-3-phenylpropyl)-...)
Affinity DataIC50: 0.300nMAssay Description:Antagonist activity at CCR5 receptor expressed in HeLa-P4 cells co-expressing CD4 assessed as inhibition of infusion to HIV gp120 expressed in CHO-ta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50334980(endo-N-((S)-3-(3-(5-acetyl-2-methyl-4,5,6,7-tetrah...)
Affinity DataIC50: 0.400nMAssay Description:Antagonist activity at CCR5 receptor expressed in HeLa-P4 cells co-expressing CD4 assessed as inhibition of infusion to HIV gp120 expressed in CHO-ta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50334979(endo-N-((S)-3-(3-(2-methyl-5-propionyl-4,5,6,7-tet...)
Affinity DataIC50: 0.400nMAssay Description:Antagonist activity at CCR5 receptor expressed in HeLa-P4 cells co-expressing CD4 assessed as inhibition of infusion to HIV gp120 expressed in CHO-ta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50334977(endo-N-((S)-3-(3-(5-isobutyryl-2-methyl-4,5,6,7-te...)
Affinity DataIC50: 0.400nMAssay Description:Antagonist activity at CCR5 receptor expressed in HeLa-P4 cells co-expressing CD4 assessed as inhibition of infusion to HIV gp120 expressed in CHO-ta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50334971(endo-N-((S)-3-(3-(2-methyl-1H-benzo[d]imidazol-1-y...)
Affinity DataIC50: 0.5nMAssay Description:Antagonist activity at CCR5 receptor expressed in HeLa-P4 cells co-expressing CD4 assessed as inhibition of infusion to HIV gp120 expressed in CHO-ta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50334976(endo-methyl(S)-3-(3-(5-acetyl-2-methyl-4,5,6,7-tet...)
Affinity DataIC50: 0.600nMAssay Description:Antagonist activity at CCR5 receptor expressed in HeLa-P4 cells co-expressing CD4 assessed as inhibition of infusion to HIV gp120 expressed in CHO-ta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50334972(endo-4,4-difluoro-N-((S)-3-(3-(5-isopropyl-3-methy...)
Affinity DataIC50: 1.40nMAssay Description:Antagonist activity at CCR5 receptor expressed in HeLa-P4 cells co-expressing CD4 assessed as inhibition of infusion to HIV gp120 expressed in CHO-ta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50334982(endo-N-((S)-3-(3-(2-methyl-5-(methylsulfonyl)-4,5,...)
Affinity DataIC50: 2nMAssay Description:Antagonist activity at CCR5 receptor expressed in HeLa-P4 cells co-expressing CD4 assessed as inhibition of infusion to HIV gp120 expressed in CHO-ta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50334981(endo-N-((S)-3-(3-(5-isopropyl-2-methyl-4,5,6,7-tet...)
Affinity DataIC50: 3nMAssay Description:Antagonist activity at CCR5 receptor expressed in HeLa-P4 cells co-expressing CD4 assessed as inhibition of infusion to HIV gp120 expressed in CHO-ta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50334983(endo-N-((S)-3-(3-(2,5-dimethyl-4,5,6,7-tetrahydro-...)
Affinity DataIC50: 5nMAssay Description:Antagonist activity at CCR5 receptor expressed in HeLa-P4 cells co-expressing CD4 assessed as inhibition of infusion to HIV gp120 expressed in CHO-ta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50334985(endo-N-((S)-3-(3-(2-methyl-4,5,6,7-tetrahydro-3H-i...)
Affinity DataIC50: 9nMAssay Description:Antagonist activity at CCR5 receptor expressed in HeLa-P4 cells co-expressing CD4 assessed as inhibition of infusion to HIV gp120 expressed in CHO-ta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
LigandPNGBDBM50334969(endo-N-((S)-1-(3-fluorophenyl)-3-(3-(2-methyl-5-(p...)
Affinity DataIC50: 10nMAssay Description:Displacement of [3H]-dofetilide from human ERG expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50334984(endo-N-((S)-3-(3-(5-benzyl-2-methyl-4,5,6,7-tetrah...)
Affinity DataIC50: 29nMAssay Description:Antagonist activity at CCR5 receptor expressed in HeLa-P4 cells co-expressing CD4 assessed as inhibition of infusion to HIV gp120 expressed in CHO-ta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
LigandPNGBDBM50334970(endo-N-((S)-1-(3-fluorophenyl)-3-(3-(2-methyl-5-(p...)
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [3H]-dofetilide from human ERG expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
LigandPNGBDBM50334971(endo-N-((S)-3-(3-(2-methyl-1H-benzo[d]imidazol-1-y...)
Affinity DataIC50: 1.50E+3nMAssay Description:Displacement of [3H]-dofetilide from human ERG expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
LigandPNGBDBM50334968(Methyl 1-endo-{8-[(3S)-3-(Acetamido)-3-(3-fluoroph...)
Affinity DataIC50: 2.00E+3nMAssay Description:Displacement of [3H]-dofetilide from human ERG expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
LigandPNGBDBM50334972(endo-4,4-difluoro-N-((S)-3-(3-(5-isopropyl-3-methy...)
Affinity DataIC50: 4.23E+3nMAssay Description:Displacement of [3H]-dofetilide from human ERG expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
LigandPNGBDBM50334963(endo-N-((S)-1-(3-fluorophenyl)-3-(3-(2-methyl-5-pi...)
Affinity DataIC50: 5.00E+3nMAssay Description:Displacement of [3H]-dofetilide from human ERG expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
LigandPNGBDBM50334967(endo-N-((S)-3-(3-(5-acetyl-2-methyl-4,5,6,7-tetrah...)
Affinity DataIC50: 5.00E+3nMAssay Description:Displacement of [3H]-dofetilide from human ERG expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
LigandPNGBDBM50334966(endo-N-((S)-1-(3-fluorophenyl)-3-(3-(2-methyl-5-pr...)
Affinity DataIC50: 5.00E+3nMAssay Description:Displacement of [3H]-dofetilide from human ERG expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
LigandPNGBDBM50334965(endo-N-((S)-3-(3-(5-butyryl-2-methyl-4,5,6,7-tetra...)
Affinity DataIC50: 6.00E+3nMAssay Description:Displacement of [3H]-dofetilide from human ERG expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
LigandPNGBDBM50334964(N-{(1S)-3-[3-endo-(5-Isobutyryl-2-methyl-4,5,6,7-t...)
Affinity DataIC50: 1.20E+4nMAssay Description:Displacement of [3H]-dofetilide from human ERG expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed