Compile Data Set for Download or QSAR
Report error Found 46 Enz. Inhib. hit(s) with all data for entry = 50032782
TargetALK tyrosine kinase receptor(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50334604(2-(7-(5-chloro-4-(2-methoxy-4-(2-methoxyethoxy)phe...)
Affinity DataIC50: 4nMAssay Description:Inhibition of ALKMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50334601(2-(7-(5-chloro-4-(2-methoxyphenylamino)pyrimidin-2...)
Affinity DataIC50: 4nMAssay Description:Inhibition of ALKMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50334595(5-chloro-N2,N4-bis(2-methoxy-4-morpholinophenyl)py...)
Affinity DataIC50: 4nMAssay Description:Inhibition of ALKMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50334593(2-(7-(5-chloro-4-(2-methoxy-4-morpholinophenylamin...)
Affinity DataIC50: 4nMAssay Description:Inhibition of ALKMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50334606(2-(7-(5-chloro-4-(2,4-dimethoxyphenylamino)pyrimid...)
Affinity DataIC50: 5nMAssay Description:Inhibition of ALKMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50334594(2-(5-chloro-2-(2-methoxy-4-morpholinophenylamino)p...)
Affinity DataIC50: 5nMAssay Description:Inhibition of ALKMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50334602(4-(5-chloro-2-(3-(2-(dimethylamino)-2-oxoethyl)-8-...)
Affinity DataIC50: 6nMAssay Description:Inhibition of ALKMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50334603(2-(7-(5-chloro-4-(2-methoxy-4-morpholinophenylamin...)
Affinity DataIC50: 6nMAssay Description:Inhibition of ALKMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50334605(2-(7-(5-chloro-4-(4-cyano-2-methoxyphenylamino)pyr...)
Affinity DataIC50: 7nMAssay Description:Inhibition of ALKMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50334597(5-chloro-N2-(8-methoxy-3-(2-methoxyethyl)-2,3,4,5-...)
Affinity DataIC50: 7nMAssay Description:Inhibition of ALKMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50334599(5-chloro-N2-(8-methoxy-3-(2-(methylsulfonyl)ethyl)...)
Affinity DataIC50: 10nMAssay Description:Inhibition of ALKMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInsulin receptor(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50334594(2-(5-chloro-2-(2-methoxy-4-morpholinophenylamino)p...)
Affinity DataIC50: 25nMAssay Description:Inhibition of insulin receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50334593(2-(7-(5-chloro-4-(2-methoxy-4-morpholinophenylamin...)
Affinity DataIC50: 30nMAssay Description:Inhibition of ALK by cell based assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50334596(7-(5-chloro-4-(2-methoxy-4-morpholinophenylamino)p...)
Affinity DataIC50: 34nMAssay Description:Inhibition of ALKMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50334606(2-(7-(5-chloro-4-(2,4-dimethoxyphenylamino)pyrimid...)
Affinity DataIC50: 40nMAssay Description:Inhibition of ALK by cell based assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50334604(2-(7-(5-chloro-4-(2-methoxy-4-(2-methoxyethoxy)phe...)
Affinity DataIC50: 40nMAssay Description:Inhibition of ALK by cell based assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50334600(2-(7-(5-chloro-4-(4-morpholinophenylamino)pyrimidi...)
Affinity DataIC50: 49nMAssay Description:Inhibition of ALKMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50334594(2-(5-chloro-2-(2-methoxy-4-morpholinophenylamino)p...)
Affinity DataIC50: 50nMAssay Description:Inhibition of ALK by cell based assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50334598(5-chloro-N2-(3-(2,2-difluoroethyl)-8-methoxy-2,3,4...)
Affinity DataIC50: 58nMAssay Description:Inhibition of ALKMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInsulin receptor(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50334601(2-(7-(5-chloro-4-(2-methoxyphenylamino)pyrimidin-2...)
Affinity DataIC50: 62nMAssay Description:Inhibition of insulin receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50334602(4-(5-chloro-2-(3-(2-(dimethylamino)-2-oxoethyl)-8-...)
Affinity DataIC50: 65nMAssay Description:Inhibition of ALK by cell based assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50334605(2-(7-(5-chloro-4-(4-cyano-2-methoxyphenylamino)pyr...)
Affinity DataIC50: 65nMAssay Description:Inhibition of ALK by cell based assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50334601(2-(7-(5-chloro-4-(2-methoxyphenylamino)pyrimidin-2...)
Affinity DataIC50: 65nMAssay Description:Inhibition of ALK by cell based assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50334603(2-(7-(5-chloro-4-(2-methoxy-4-morpholinophenylamin...)
Affinity DataIC50: 100nMAssay Description:Inhibition of ALK by cell based assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50334599(5-chloro-N2-(8-methoxy-3-(2-(methylsulfonyl)ethyl)...)
Affinity DataIC50: 100nMAssay Description:Inhibition of ALK by cell based assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50334595(5-chloro-N2,N4-bis(2-methoxy-4-morpholinophenyl)py...)
Affinity DataIC50: 120nMAssay Description:Inhibition of ALK by cell based assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50334597(5-chloro-N2-(8-methoxy-3-(2-methoxyethyl)-2,3,4,5-...)
Affinity DataIC50: 150nMAssay Description:Inhibition of ALK by cell based assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50334596(7-(5-chloro-4-(2-methoxy-4-morpholinophenylamino)p...)
Affinity DataIC50: 175nMAssay Description:Inhibition of ALK by cell based assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInsulin receptor(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50334606(2-(7-(5-chloro-4-(2,4-dimethoxyphenylamino)pyrimid...)
Affinity DataIC50: 189nMAssay Description:Inhibition of insulin receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInsulin receptor(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50334605(2-(7-(5-chloro-4-(4-cyano-2-methoxyphenylamino)pyr...)
Affinity DataIC50: 233nMAssay Description:Inhibition of insulin receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInsulin receptor(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50334604(2-(7-(5-chloro-4-(2-methoxy-4-(2-methoxyethoxy)phe...)
Affinity DataIC50: 351nMAssay Description:Inhibition of insulin receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInsulin receptor(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50334600(2-(7-(5-chloro-4-(4-morpholinophenylamino)pyrimidi...)
Affinity DataIC50: 504nMAssay Description:Inhibition of insulin receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInsulin receptor(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50334602(4-(5-chloro-2-(3-(2-(dimethylamino)-2-oxoethyl)-8-...)
Affinity DataIC50: 573nMAssay Description:Inhibition of insulin receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2C19(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50334593(2-(7-(5-chloro-4-(2-methoxy-4-morpholinophenylamin...)
Affinity DataIC50: 800nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInsulin receptor(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50334593(2-(7-(5-chloro-4-(2-methoxy-4-morpholinophenylamin...)
Affinity DataIC50: 1.38E+3nMAssay Description:Inhibition of insulin receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2C9(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50334593(2-(7-(5-chloro-4-(2-methoxy-4-morpholinophenylamin...)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInsulin receptor(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50334595(5-chloro-N2,N4-bis(2-methoxy-4-morpholinophenyl)py...)
Affinity DataIC50: 1.86E+3nMAssay Description:Inhibition of insulin receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 3A4(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50334593(2-(7-(5-chloro-4-(2-methoxy-4-morpholinophenylamin...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInsulin receptor(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50334597(5-chloro-N2-(8-methoxy-3-(2-methoxyethyl)-2,3,4,5-...)
Affinity DataIC50: 2.69E+3nMAssay Description:Inhibition of insulin receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInsulin receptor(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50334603(2-(7-(5-chloro-4-(2-methoxy-4-morpholinophenylamin...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of insulin receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInsulin receptor(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50334599(5-chloro-N2-(8-methoxy-3-(2-(methylsulfonyl)ethyl)...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of insulin receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50334593(2-(7-(5-chloro-4-(2-methoxy-4-morpholinophenylamin...)
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibition of human ERG by patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInsulin receptor(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50334596(7-(5-chloro-4-(2-methoxy-4-morpholinophenylamino)p...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of insulin receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInsulin receptor(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50334598(5-chloro-N2-(3-(2,2-difluoroethyl)-8-methoxy-2,3,4...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of insulin receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 1A2(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50334593(2-(7-(5-chloro-4-(2-methoxy-4-morpholinophenylamin...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of CYP1A2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2D6(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50334593(2-(7-(5-chloro-4-(2-methoxy-4-morpholinophenylamin...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In DepthDetails Article
PubMed