Compile Data Set for Download or QSAR
Report error Found 42 Enz. Inhib. hit(s) with all data for entry = 50032591
TargetMitogen-activated protein kinase 14(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50331633(5-amino-1-butyl-N-(5-(isoxazol-3-ylcarbamoyl)-2-me...)
Affinity DataIC50: 2nMAssay Description:Inhibition of human recombinant p38alphaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50331631(5-amino-1-(4-fluorophenyl)-N-(5-(isoxazol-3-ylcarb...)
Affinity DataIC50: 2nMAssay Description:Inhibition of human recombinant p38alphaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50331630(5-amino-N-(5-(1-ethyl-1H-pyrazol-5-ylcarbamoyl)-2-...)
Affinity DataIC50: 2nMAssay Description:Inhibition of human recombinant p38alphaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50331629(5-amino-1-(2-fluorophenyl)-N-(5-(isoxazol-3-ylcarb...)
Affinity DataIC50: 2nMAssay Description:Inhibition of human recombinant p38alphaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50331626(5-amino-N-(5-(isoxazol-3-ylcarbamoyl)-2-methylphen...)
Affinity DataIC50: 2nMAssay Description:Inhibition of human recombinant p38alphaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50331625(5-amino-N-(5-(isoxazol-3-ylcarbamoyl)-2-methylphen...)
Affinity DataIC50: 3nMAssay Description:Inhibition of human recombinant p38alphaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50331627(5-amino-N-(5-(1-ethyl-1H-pyrazol-5-ylcarbamoyl)-2-...)
Affinity DataIC50: 3nMAssay Description:Inhibition of human recombinant p38alphaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50331636(5-(ethylamino)-N-(5-(isoxazol-3-ylcarbamoyl)-2-met...)
Affinity DataIC50: 4nMAssay Description:Inhibition of human recombinant p38alphaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50331628(5-amino-1-(2-fluorophenyl)-N-(2-methyl-5-(1-methyl...)
Affinity DataIC50: 4nMAssay Description:Inhibition of human recombinant p38alphaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50331637(5-(ethylamino)-N-(5-(isoxazol-3-ylcarbamoyl)-2-met...)
Affinity DataIC50: 5nMAssay Description:Inhibition of human recombinant p38alphaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50331634(N-(5-(isoxazol-3-ylcarbamoyl)-2-methylphenyl)-5-(m...)
Affinity DataIC50: 5nMAssay Description:Inhibition of human recombinant p38alphaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50331624(5-amino-N-(5-(1-ethyl-1H-pyrazol-5-ylcarbamoyl)-2-...)
Affinity DataIC50: 5nMAssay Description:Inhibition of human recombinant p38alphaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50331635(5-(ethylamino)-N-(5-(ethylcarbamoyl)-2-methylpheny...)
Affinity DataIC50: 6nMAssay Description:Inhibition of human recombinant p38alphaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50331623(5-amino-N-(2-methyl-5-(1-methyl-1H-pyrazol-5-ylcar...)
Affinity DataIC50: 7nMAssay Description:Inhibition of human recombinant p38alphaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50331622(5-amino-N-(5-(cyclopropylcarbamoyl)-2-methylphenyl...)
Affinity DataIC50: 7nMAssay Description:Inhibition of human recombinant p38alphaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50331632(5-amino-1-butyl-N-(2-methyl-5-(1-methyl-1H-pyrazol...)
Affinity DataIC50: 7nMAssay Description:Inhibition of human recombinant p38alphaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50331621(5-amino-N-(5-(ethylcarbamoyl)-2-methylphenyl)-1-ph...)
Affinity DataIC50: 8nMAssay Description:Inhibition of human recombinant p38alphaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50331619(N,4-dimethyl-3-(1-phenyl-1H-pyrazolo[3,4-d]pyrimid...)
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant p38alphaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50331620(5-amino-N-(2-methyl-5-(methylcarbamoyl)phenyl)-1-p...)
Affinity DataIC50: 14nMAssay Description:Inhibition of human recombinant p38alphaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50331629(5-amino-1-(2-fluorophenyl)-N-(5-(isoxazol-3-ylcarb...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of Tyk2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50331629(5-amino-1-(2-fluorophenyl)-N-(5-(isoxazol-3-ylcarb...)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSignal transducer and activator of transcription 3(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50331629(5-amino-1-(2-fluorophenyl)-N-(5-(isoxazol-3-ylcarb...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of STAT3More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50331629(5-amino-1-(2-fluorophenyl)-N-(5-(isoxazol-3-ylcarb...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Jak3More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2D6(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50331629(5-amino-1-(2-fluorophenyl)-N-(5-(isoxazol-3-ylcarb...)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 3A4(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50331629(5-amino-1-(2-fluorophenyl)-N-(5-(isoxazol-3-ylcarb...)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 1A2(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50331629(5-amino-1-(2-fluorophenyl)-N-(5-(isoxazol-3-ylcarb...)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of CYP1A2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50331629(5-amino-1-(2-fluorophenyl)-N-(5-(isoxazol-3-ylcarb...)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of BtkMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase PLK1(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50331629(5-amino-1-(2-fluorophenyl)-N-(5-(isoxazol-3-ylcarb...)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of PLK1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50331629(5-amino-1-(2-fluorophenyl)-N-(5-(isoxazol-3-ylcarb...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of DGATMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein kinase C zeta type(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50331629(5-amino-1-(2-fluorophenyl)-N-(5-(isoxazol-3-ylcarb...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of PKCzetaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2C9(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50331629(5-amino-1-(2-fluorophenyl)-N-(5-(isoxazol-3-ylcarb...)
Affinity DataIC50: 2.30E+4nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2C19(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50331629(5-amino-1-(2-fluorophenyl)-N-(5-(isoxazol-3-ylcarb...)
Affinity DataIC50: 2.30E+4nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMAP kinase-activated protein kinase 2(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50331629(5-amino-1-(2-fluorophenyl)-N-(5-(isoxazol-3-ylcarb...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of MK2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein kinase C beta type(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50331629(5-amino-1-(2-fluorophenyl)-N-(5-(isoxazol-3-ylcarb...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of PKAbetaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein kinase C delta type(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50331629(5-amino-1-(2-fluorophenyl)-N-(5-(isoxazol-3-ylcarb...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of PKCdeltaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein kinase C alpha type(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50331629(5-amino-1-(2-fluorophenyl)-N-(5-(isoxazol-3-ylcarb...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of PKCalphaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50331629(5-amino-1-(2-fluorophenyl)-N-(5-(isoxazol-3-ylcarb...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of IGF-1RMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50331629(5-amino-1-(2-fluorophenyl)-N-(5-(isoxazol-3-ylcarb...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of SykMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50331629(5-amino-1-(2-fluorophenyl)-N-(5-(isoxazol-3-ylcarb...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of FGFR1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50331629(5-amino-1-(2-fluorophenyl)-N-(5-(isoxazol-3-ylcarb...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of ItkMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50331629(5-amino-1-(2-fluorophenyl)-N-(5-(isoxazol-3-ylcarb...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50331629(5-amino-1-(2-fluorophenyl)-N-(5-(isoxazol-3-ylcarb...)
Affinity DataIC50: 1.60E+5nMAssay Description:Inhibition of human ERG by flux assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed