Compile Data Set for Download or QSAR
Report error Found 20 Enz. Inhib. hit(s) with all data for entry = 50032572
TargetSodium/glucose cotransporter 2(Human)
Green Cross

Curated by ChEMBL
LigandPNGBDBM20880(CHEMBL429910 | C-aryl glucoside, 6 | BMS-512148 | ...)
Affinity DataIC50: 0.490nMAssay Description:Inhibition of human SGLT2 assessed as inhibition of methyl-alpha-D-glucopyranoside uptake by cell based assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetSodium/glucose cotransporter 2(Human)
Green Cross

Curated by ChEMBL
LigandPNGBDBM50331214((2S,3R,4S,5S,6R)-2-(4-chloro-3-((5-(methylthio)pyr...)
Affinity DataIC50: 10.7nMAssay Description:Inhibition of human SGLT2 assessed as inhibition of methyl-alpha-D-glucopyranoside uptake by cell based assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Green Cross

Curated by ChEMBL
LigandPNGBDBM50331231((2S,3R,4S,5S,6R)-2-(4-chloro-3-((5-(thiophen-2-yl)...)
Affinity DataIC50: 17.1nMAssay Description:Inhibition of human SGLT2 assessed as inhibition of methyl-alpha-D-glucopyranoside uptake by cell based assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Green Cross

Curated by ChEMBL
LigandPNGBDBM50331230((2S,3R,4S,5S,6R)-2-(4-chloro-3-((5-(furan-3-yl)pyr...)
Affinity DataIC50: 34.5nMAssay Description:Inhibition of human SGLT2 assessed as inhibition of methyl-alpha-D-glucopyranoside uptake by cell based assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Green Cross

Curated by ChEMBL
LigandPNGBDBM50331229((2S,3R,4S,5S,6R)-2-(4-chloro-3-((5-(furan-2-yl)pyr...)
Affinity DataIC50: 36.8nMAssay Description:Inhibition of human SGLT2 assessed as inhibition of methyl-alpha-D-glucopyranoside uptake by cell based assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Green Cross

Curated by ChEMBL
LigandPNGBDBM50331215((2S,3R,4S,5S,6R)-2-(4-chloro-3-((5-(ethylthio)pyri...)
Affinity DataIC50: 39.4nMAssay Description:Inhibition of human SGLT2 assessed as inhibition of methyl-alpha-D-glucopyranoside uptake by cell based assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Green Cross

Curated by ChEMBL
LigandPNGBDBM50331223((2S,3R,4S,5S,6R)-2-(4-chloro-3-((2-ethoxypyrimidin...)
Affinity DataIC50: 46.9nMAssay Description:Inhibition of human SGLT2 assessed as inhibition of methyl-alpha-D-glucopyranoside uptake by cell based assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Green Cross

Curated by ChEMBL
LigandPNGBDBM50331213((2S,3R,4S,5S,6R)-2-(4-chloro-3-((5-(thiophen-3-yl)...)
Affinity DataIC50: 64.4nMAssay Description:Inhibition of human SGLT2 assessed as inhibition of methyl-alpha-D-glucopyranoside uptake by cell based assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Green Cross

Curated by ChEMBL
LigandPNGBDBM50331227((2S,3R,4S,5S,6R)-2-(4-chloro-3-((5-phenylpyrimidin...)
Affinity DataIC50: 73.6nMAssay Description:Inhibition of human SGLT2 assessed as inhibition of methyl-alpha-D-glucopyranoside uptake by cell based assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Green Cross

Curated by ChEMBL
LigandPNGBDBM50331226((2S,3R,4S,5S,6R)-2-(4-chloro-3-((2-(methylthio)pyr...)
Affinity DataIC50: 76nMAssay Description:Inhibition of human SGLT2 assessed as inhibition of methyl-alpha-D-glucopyranoside uptake by cell based assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Green Cross

Curated by ChEMBL
LigandPNGBDBM50331228((2S,3R,4S,5S,6R)-2-(4-chloro-3-((5-(4-fluorophenyl...)
Affinity DataIC50: 107nMAssay Description:Inhibition of human SGLT2 assessed as inhibition of methyl-alpha-D-glucopyranoside uptake by cell based assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Green Cross

Curated by ChEMBL
LigandPNGBDBM50331220((2S,3R,4S,5S,6R)-2-(4-chloro-3-((2-(thiophen-3-yl)...)
Affinity DataIC50: 113nMAssay Description:Inhibition of human SGLT2 assessed as inhibition of methyl-alpha-D-glucopyranoside uptake by cell based assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Green Cross

Curated by ChEMBL
LigandPNGBDBM50331218((2S,3R,4S,5S,6R)-2-(4-chloro-3-((2-(4-fluorophenyl...)
Affinity DataIC50: 119nMAssay Description:Inhibition of human SGLT2 assessed as inhibition of methyl-alpha-D-glucopyranoside uptake by cell based assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Green Cross

Curated by ChEMBL
LigandPNGBDBM50331217((2S,3R,4S,5S,6R)-2-(4-chloro-3-((2-phenylpyrimidin...)
Affinity DataIC50: 124nMAssay Description:Inhibition of human SGLT2 assessed as inhibition of methyl-alpha-D-glucopyranoside uptake by cell based assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Green Cross

Curated by ChEMBL
LigandPNGBDBM50331225((2S,3R,4S,5S,6R)-2-(4-chloro-3-((2-(heptyloxy)pyri...)
Affinity DataIC50: 130nMAssay Description:Inhibition of human SGLT2 assessed as inhibition of methyl-alpha-D-glucopyranoside uptake by cell based assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Green Cross

Curated by ChEMBL
LigandPNGBDBM50331221(5-(2-chloro-5-((2S,3R,4S,5S,6R)-6-ethyl-3,4,5-trih...)
Affinity DataIC50: 189nMAssay Description:Inhibition of human SGLT2 assessed as inhibition of methyl-alpha-D-glucopyranoside uptake by cell based assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Green Cross

Curated by ChEMBL
LigandPNGBDBM50331222((2S,3R,4S,5S,6R)-2-(3-((2-(1,3,4-thiadiazol-2-yl)p...)
Affinity DataIC50: 223nMAssay Description:Inhibition of human SGLT2 assessed as inhibition of methyl-alpha-D-glucopyranoside uptake by cell based assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Green Cross

Curated by ChEMBL
LigandPNGBDBM50331219((2S,3R,4S,5S,6R)-2-(4-chloro-3-((2-(furan-3-yl)pyr...)
Affinity DataIC50: 246nMAssay Description:Inhibition of human SGLT2 assessed as inhibition of methyl-alpha-D-glucopyranoside uptake by cell based assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Green Cross

Curated by ChEMBL
LigandPNGBDBM50331224((2S,3R,4S,5S,6R)-2-(3-((2-butoxypyrimidin-5-yl)met...)
Affinity DataIC50: 447nMAssay Description:Inhibition of human SGLT2 assessed as inhibition of methyl-alpha-D-glucopyranoside uptake by cell based assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Green Cross

Curated by ChEMBL
LigandPNGBDBM50331216((2S,3R,4S,5S,6R)-2-(3-((2-butylpyrimidin-5-yl)meth...)
Affinity DataIC50: 8.87E+3nMAssay Description:Inhibition of human SGLT2 assessed as inhibition of methyl-alpha-D-glucopyranoside uptake by cell based assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed