Compile Data Set for Download or QSAR
Report error Found 46 Enz. Inhib. hit(s) with all data for entry = 50032527
TargetKinesin-like protein KIF11(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50330546(4-Furan-6-methyl-N-(4-methoxyphenyl)-4,7-dihydro-2...)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of human full-length Eg5 ATPase activity expressed in Escherichia coli assessed as release of inorganic phosphate after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50330547(4-Thiophene-6-methyl-N-(4-methoxyphenyl)-4,7-dihyd...)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of human full-length Eg5 ATPase activity expressed in Escherichia coli assessed as release of inorganic phosphate after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50198311((R)-N-(1-(3-benzyl-7-chloro-4-oxo-3,4-dihydroquina...)
Affinity DataIC50: 29nMAssay Description:Inhibition of human full-length Eg5 ATPase activity expressed in Escherichia coli assessed as release of inorganic phosphate after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50330548(4-Phenyl-6-methyl-N-(4-fluorophenyl)-4,7-dihydro-2...)
Affinity DataIC50: 140nMAssay Description:Inhibition of human full-length Eg5 ATPase activity expressed in Escherichia coli assessed as release of inorganic phosphate after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50330549(4-Phenyl-6-methyl-N-(3-chloro-4-fluorophenyl)-4,7-...)
Affinity DataIC50: 170nMAssay Description:Inhibition of human full-length Eg5 ATPase activity expressed in Escherichia coli assessed as release of inorganic phosphate after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50330550(N-(4-chlorophenyl)-2,7,7-trimethyl-5-oxo-4-phenyl-...)
Affinity DataIC50: 180nMAssay Description:Inhibition of human full-length Eg5 ATPase activity expressed in Escherichia coli assessed as release of inorganic phosphate after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50330551(4-Phenyl-6-methyl-N-(4-nitrophenyl)-4,7-dihydro-2H...)
Affinity DataIC50: 200nMAssay Description:Inhibition of human full-length Eg5 ATPase activity expressed in Escherichia coli assessed as release of inorganic phosphate after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50330552(4-Thiophene-6-methyl-N-(4-trifluoromethylphenyl)-4...)
Affinity DataIC50: 320nMAssay Description:Inhibition of human full-length Eg5 ATPase activity expressed in Escherichia coli assessed as release of inorganic phosphate after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50330553(4-Phenyl-6-methyl-N-(4-trifluoromethylphenyl)-4,7-...)
Affinity DataIC50: 400nMAssay Description:Inhibition of human full-length Eg5 ATPase activity expressed in Escherichia coli assessed as release of inorganic phosphate after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50330554(4-Furan-6-methyl-N-(3-chloro-4-fluorophenyl)-4,7-d...)
Affinity DataIC50: 400nMAssay Description:Inhibition of human full-length Eg5 ATPase activity expressed in Escherichia coli assessed as release of inorganic phosphate after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50330555(4-Thiophene-6-methyl-N-(3-chloro-4-fluorophenyl)-4...)
Affinity DataIC50: 440nMAssay Description:Inhibition of human full-length Eg5 ATPase activity expressed in Escherichia coli assessed as release of inorganic phosphate after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50330556(4-Thiophene-6-methyl-N-(4-nitrophenyl)-4,7-dihydro...)
Affinity DataIC50: 820nMAssay Description:Inhibition of human full-length Eg5 ATPase activity expressed in Escherichia coli assessed as release of inorganic phosphate after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50330557(N-(3-Chloro-4-fluorobenzyl)-4-furan-2-methyl-1,4-d...)
Affinity DataIC50: 960nMAssay Description:Inhibition of human full-length Eg5 ATPase activity expressed in Escherichia coli assessed as release of inorganic phosphate after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50330558(4-Furan-6-methyl-N-(4-trifluoromethylphenyl)-4,7-d...)
Affinity DataIC50: 1.06E+3nMAssay Description:Inhibition of human full-length Eg5 ATPase activity expressed in Escherichia coli assessed as release of inorganic phosphate after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetAurora kinase A(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50330559(N-(4-Trifluoromethylbenzyl)-4-furan-2-methyl-1,4-d...)
Affinity DataIC50: 1.32E+3nMAssay Description:Inhibition of human purified recombinant aurora-A kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50330560(N-(4-Methoxybenzyl)-4-furan-2-methyl-1,4-dihydrobe...)
Affinity DataIC50: 2.46E+3nMAssay Description:Inhibition of human full-length Eg5 ATPase activity expressed in Escherichia coli assessed as release of inorganic phosphate after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50330561(4-Furan-6-methyl-N-(4-nitrophenyl)-4,7-dihydro-2Hp...)
Affinity DataIC50: 2.76E+3nMAssay Description:Inhibition of human full-length Eg5 ATPase activity expressed in Escherichia coli assessed as release of inorganic phosphate after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50330562(4-Phenyl-6-methyl-N-(4-methoxyphenyl)-4,7-dihydro-...)
Affinity DataIC50: 2.82E+3nMAssay Description:Inhibition of human full-length Eg5 ATPase activity expressed in Escherichia coli assessed as release of inorganic phosphate after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetAurora kinase A(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50330563(N-(4-Nitrobenzyl)-4-furan-2-methyl-1,4-dihydrobenz...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human purified recombinant aurora-A kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50330559(N-(4-Trifluoromethylbenzyl)-4-furan-2-methyl-1,4-d...)
Affinity DataIC50: 3.32E+3nMAssay Description:Inhibition of human full-length Eg5 ATPase activity expressed in Escherichia coli assessed as release of inorganic phosphate after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetAurora kinase A(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50224731(4-(6-chloro-3H-imidazo[4,5-b]pyridin-2-yl)-N,N-dim...)
Affinity DataIC50: 4.97E+3nMAssay Description:Inhibition of human purified recombinant aurora-A kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50216502(monastrol | rac-monastrol | 4-(3-hydroxy-phenyl)-6...)
Affinity DataIC50: 5.47E+3nMAssay Description:Inhibition of human full-length Eg5 ATPase activity expressed in Escherichia coli assessed as release of inorganic phosphate after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50330564(N-(4-Fluorobenzyl)-4-furan-2-methyl-1,4-dihydroben...)
Affinity DataIC50: 5.65E+3nMAssay Description:Inhibition of human full-length Eg5 ATPase activity expressed in Escherichia coli assessed as release of inorganic phosphate after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetAurora kinase A(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50330557(N-(3-Chloro-4-fluorobenzyl)-4-furan-2-methyl-1,4-d...)
Affinity DataIC50: 5.73E+3nMAssay Description:Inhibition of human purified recombinant aurora-A kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetAurora kinase A(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50330564(N-(4-Fluorobenzyl)-4-furan-2-methyl-1,4-dihydroben...)
Affinity DataIC50: 6.15E+3nMAssay Description:Inhibition of human purified recombinant aurora-A kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetAurora kinase A(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50330560(N-(4-Methoxybenzyl)-4-furan-2-methyl-1,4-dihydrobe...)
Affinity DataIC50: 7.58E+3nMAssay Description:Inhibition of human purified recombinant aurora-A kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetAurora kinase A(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50330565(4-Furan-6-methyl-N-(4-fluorophenyl)-4,7-dihydro-2H...)
Affinity DataIC50: 8.10E+3nMAssay Description:Inhibition of human purified recombinant aurora-A kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetAurora kinase A(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50330546(4-Furan-6-methyl-N-(4-methoxyphenyl)-4,7-dihydro-2...)
Affinity DataIC50: 9.25E+3nMAssay Description:Inhibition of human purified recombinant aurora-A kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50330565(4-Furan-6-methyl-N-(4-fluorophenyl)-4,7-dihydro-2H...)
Affinity DataIC50: 1.04E+4nMAssay Description:Inhibition of human full-length Eg5 ATPase activity expressed in Escherichia coli assessed as release of inorganic phosphate after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetAurora kinase A(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50330554(4-Furan-6-methyl-N-(3-chloro-4-fluorophenyl)-4,7-d...)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of human purified recombinant aurora-A kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50330563(N-(4-Nitrobenzyl)-4-furan-2-methyl-1,4-dihydrobenz...)
Affinity DataIC50: 2.09E+4nMAssay Description:Inhibition of human full-length Eg5 ATPase activity expressed in Escherichia coli assessed as release of inorganic phosphate after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50224731(4-(6-chloro-3H-imidazo[4,5-b]pyridin-2-yl)-N,N-dim...)
Affinity DataIC50: 4.02E+4nMAssay Description:Inhibition of human full-length Eg5 ATPase activity expressed in Escherichia coli assessed as release of inorganic phosphate after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetAurora kinase A(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50330550(N-(4-chlorophenyl)-2,7,7-trimethyl-5-oxo-4-phenyl-...)
Affinity DataIC50: 4.03E+4nMAssay Description:Inhibition of human purified recombinant aurora-A kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetAurora kinase A(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50198311((R)-N-(1-(3-benzyl-7-chloro-4-oxo-3,4-dihydroquina...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human purified recombinant aurora-A kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetAurora kinase A(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50216502(monastrol | rac-monastrol | 4-(3-hydroxy-phenyl)-6...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human purified recombinant aurora-A kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetAurora kinase A(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50330558(4-Furan-6-methyl-N-(4-trifluoromethylphenyl)-4,7-d...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human purified recombinant aurora-A kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetAurora kinase A(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50330561(4-Furan-6-methyl-N-(4-nitrophenyl)-4,7-dihydro-2Hp...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human purified recombinant aurora-A kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetAurora kinase A(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50330555(4-Thiophene-6-methyl-N-(3-chloro-4-fluorophenyl)-4...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human purified recombinant aurora-A kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetAurora kinase A(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50330552(4-Thiophene-6-methyl-N-(4-trifluoromethylphenyl)-4...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human purified recombinant aurora-A kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetAurora kinase A(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50330556(4-Thiophene-6-methyl-N-(4-nitrophenyl)-4,7-dihydro...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human purified recombinant aurora-A kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetAurora kinase A(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50330547(4-Thiophene-6-methyl-N-(4-methoxyphenyl)-4,7-dihyd...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human purified recombinant aurora-A kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetAurora kinase A(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50330548(4-Phenyl-6-methyl-N-(4-fluorophenyl)-4,7-dihydro-2...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human purified recombinant aurora-A kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetAurora kinase A(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50330549(4-Phenyl-6-methyl-N-(3-chloro-4-fluorophenyl)-4,7-...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human purified recombinant aurora-A kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetAurora kinase A(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50330553(4-Phenyl-6-methyl-N-(4-trifluoromethylphenyl)-4,7-...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human purified recombinant aurora-A kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetAurora kinase A(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50330551(4-Phenyl-6-methyl-N-(4-nitrophenyl)-4,7-dihydro-2H...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human purified recombinant aurora-A kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetAurora kinase A(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50330562(4-Phenyl-6-methyl-N-(4-methoxyphenyl)-4,7-dihydro-...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human purified recombinant aurora-A kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed