Compile Data Set for Download or QSAR
Report error Found 16 Enz. Inhib. hit(s) with all data for entry = 50032493
TargetBifunctional epoxide hydrolase 2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50330100(N-(4-(3-(pyridin-3-yl)-5-(trifluoromethyl)-1H-pyra...)
Affinity DataIC50: 1nMAssay Description:Displacement of [3H]-cDPPO from human Ephx2 by cell-based assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50330103(N-(5-(3-(pyridin-3-yl)-5-(trifluoromethyl)-1H-pyra...)
Affinity DataIC50: 4.70nMAssay Description:Inhibition of human Ephx2 after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50330103(N-(5-(3-(pyridin-3-yl)-5-(trifluoromethyl)-1H-pyra...)
Affinity DataIC50: 5nMAssay Description:Displacement of [3H]-cDPPO from human Ephx2 by cell-based assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50330100(N-(4-(3-(pyridin-3-yl)-5-(trifluoromethyl)-1H-pyra...)
Affinity DataIC50: 6.20nMAssay Description:Inhibition of human Ephx2 after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50330099(N-(4-(3-(pyridin-3-yl)-5-(trifluoromethyl)-1H-pyra...)
Affinity DataIC50: 7.30nMAssay Description:Inhibition of human Ephx2 after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50330105(N-(6-(3-(pyridin-3-yl)-5-(trifluoromethyl)-1H-pyra...)
Affinity DataIC50: 8.80nMAssay Description:Inhibition of human Ephx2 after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50330104(N-(6-(3-(pyridin-3-yl)-5-(trifluoromethyl)-1H-pyra...)
Affinity DataIC50: 9.90nMAssay Description:Inhibition of human Ephx2 after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50330107(N-(5-(3-(pyridin-3-yl)-5-(trifluoromethyl)-1H-pyra...)
Affinity DataIC50: 21nMAssay Description:Inhibition of human Ephx2 after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50330098(N-(4-(3-(pyridin-3-yl)-5-(trifluoromethyl)-1H-pyra...)
Affinity DataIC50: 23nMAssay Description:Inhibition of human Ephx2 after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50330106(N-(5-(3-(pyridin-3-yl)-5-(trifluoromethyl)-1H-pyra...)
Affinity DataIC50: 28nMAssay Description:Inhibition of human Ephx2 after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 3A4(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50330103(N-(5-(3-(pyridin-3-yl)-5-(trifluoromethyl)-1H-pyra...)
Affinity DataIC50: 30nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50330097(N-(4-(5-ethyl-3-(pyridin-3-yl)-1H-pyrazol-1-yl)phe...)
Affinity DataIC50: 41nMAssay Description:Inhibition of human Ephx2 after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50330105(N-(6-(3-(pyridin-3-yl)-5-(trifluoromethyl)-1H-pyra...)
Affinity DataIC50: 83nMAssay Description:Displacement of [3H]-cDPPO from human Ephx2 by cell-based assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50330104(N-(6-(3-(pyridin-3-yl)-5-(trifluoromethyl)-1H-pyra...)
Affinity DataIC50: 397nMAssay Description:Displacement of [3H]-cDPPO from human Ephx2 by cell-based assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50330101(4-(3-(pyridin-3-yl)-5-(trifluoromethyl)-1H-pyrazol...)
Affinity DataIC50: 450nMAssay Description:Inhibition of human Ephx2 after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50330102(N-(4-(3-(pyridin-3-yl)-5-(trifluoromethyl)-1H-pyra...)
Affinity DataIC50: 650nMAssay Description:Inhibition of human Ephx2 after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed