Compile Data Set for Download or QSAR
Report error Found 30 Enz. Inhib. hit(s) with all data for entry = 50032477
LigandPNGBDBM50329853(2-(3-fluorophenyl)-1H-imidazole-4,5-dicarboxylic a...)
Affinity DataKd:  520nMAssay Description:Binding affinity to Pin1 by isothermal calorimetryMore data for this Ligand-Target Pair
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PubMed
LigandPNGBDBM50329854(4-(benzyl(phenethyl)carbamoyl)-2-phenyl-1H-imidazo...)
Affinity DataEC50:  1.00E+4nMAssay Description:Inhibition of Pin1-mediated cyclin D1 expression in serum starved human PC3 cellsMore data for this Ligand-Target Pair
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PubMed
LigandPNGBDBM50329854(4-(benzyl(phenethyl)carbamoyl)-2-phenyl-1H-imidazo...)
Affinity DataEC50:  3.00E+4nMAssay Description:Inhibition of Pin1 in serum starved human PC3 cells assessed as reduction in insulin-induced p7)S6 kinase phosphorylationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50329855(2-(3-chlorophenyl)-4-(dibenzylcarbamoyl)-1H-imidaz...)
Affinity DataKd:  1.40E+3nMAssay Description:Binding affinity to Pin1 by isothermal calorimetryMore data for this Ligand-Target Pair
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PubMed
LigandPNGBDBM50329852(2-phenyl-1H-imidazole-4,5-dicarboxylic acid | CHEM...)
Affinity DataKd:  1.70E+3nMAssay Description:Binding affinity to Pin1 by isothermal calorimetryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50329853(2-(3-fluorophenyl)-1H-imidazole-4,5-dicarboxylic a...)
Affinity DataIC50: 320nMAssay Description:Inhibition of Pin1 by PIn1 PPIase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50329873(4-((2-amino-2-oxoethyl)(benzo[d]thiazol-2-ylmethyl...)
Affinity DataIC50: 520nMAssay Description:Inhibition of Pin1 by PIn1 PPIase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50329854(4-(benzyl(phenethyl)carbamoyl)-2-phenyl-1H-imidazo...)
Affinity DataIC50: 830nMAssay Description:Inhibition of Pin1 by PIn1 PPIase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50329855(2-(3-chlorophenyl)-4-(dibenzylcarbamoyl)-1H-imidaz...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of Pin1 by PIn1 PPIase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50329852(2-phenyl-1H-imidazole-4,5-dicarboxylic acid | CHEM...)
Affinity DataIC50: 1.46E+3nMAssay Description:Inhibition of Pin1 by PIn1 PPIase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50329874(4-(benzyl(methyl)carbamoyl)-2-(3-chlorophenyl)-1H-...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of Pin1 by PIn1 PPIase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50329870(4-(dibenzylcarbamoyl)-2-phenyl-1H-imidazole-5-carb...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of Pin1 by PIn1 PPIase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50329872(4-((2-amino-2-oxoethyl)(methyl)carbamoyl)-2-phenyl...)
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of Pin1 by PIn1 PPIase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50329869(4-(benzyl(2-ethoxy-2-oxoethyl)carbamoyl)-2-phenyl-...)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of Pin1 by PIn1 PPIase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50329871(4-((carboxymethyl)(methyl)carbamoyl)-2-phenyl-1H-i...)
Affinity DataIC50: 9.40E+3nMAssay Description:Inhibition of Pin1 by PIn1 PPIase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50329867(4-(MORPHOLIN-4-YLCARBONYL)-2-PHENYL-1H-IMIDAZOLE-5...)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of Pin1 by PIn1 PPIase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50329861(2-(3-cyanophenyl)-5-methyl-1H-imidazole-4-carboxyl...)
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of Pin1 by PIn1 PPIase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50329862(2-(3-CHLORO-PHENYL)-5-METHYL-1H-IMIDAZOLE-4-CARBOX...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of Pin1 by PIn1 PPIase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50329875(2-(3-chlorophenyl)-4-(morpholine-4-carbonyl)-1H-im...)
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibition of Pin1 by PIn1 PPIase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50329859(5-methyl-2-(3-(trifluoromethyl)phenyl)-1H-imidazol...)
Affinity DataIC50: 2.30E+4nMAssay Description:Inhibition of Pin1 by PIn1 PPIase assayMore data for this Ligand-Target Pair
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PubMed
LigandPNGBDBM50329868(4-(benzyl(methyl)carbamoyl)-2-phenyl-1H-imidazole-...)
Affinity DataIC50: 3.10E+4nMAssay Description:Inhibition of Pin1 by PIn1 PPIase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50329860(5-methyl-2-m-tolyl-1H-imidazole-4-carboxylic acid ...)
Affinity DataIC50: 3.40E+4nMAssay Description:Inhibition of Pin1 by PIn1 PPIase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50329864(4-(methylcarbamoyl)-2-phenyl-1H-imidazole-5-carbox...)
Affinity DataIC50: 8.00E+4nMAssay Description:Inhibition of Pin1 by PIn1 PPIase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50329865(4-(ethylcarbamoyl)-2-phenyl-1H-imidazole-5-carboxy...)
Affinity DataIC50: 1.40E+5nMAssay Description:Inhibition of Pin1 by PIn1 PPIase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50329857(2-phenyl-1H-imidazole-4-carboxylic acid | CHEMBL12...)
Affinity DataIC50: 1.80E+5nMAssay Description:Inhibition of Pin1 by PIn1 PPIase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50329866(4-(benzylcarbamoyl)-2-phenyl-1H-imidazole-5-carbox...)
Affinity DataIC50: 2.20E+5nMAssay Description:Inhibition of Pin1 by PIn1 PPIase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50329863(2-(3-methoxyphenyl)-5-methyl-1H-imidazole-4-carbox...)
Affinity DataIC50: 2.70E+5nMAssay Description:Inhibition of Pin1 by PIn1 PPIase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50329858(5-methyl-2-phenyl-1H-imidazole-4-carboxylic acid |...)
Affinity DataIC50: 3.60E+5nMAssay Description:Inhibition of Pin1 by PIn1 PPIase assayMore data for this Ligand-Target Pair
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PubMed
LigandPNGBDBM50329856(3-(pyridin-2-yl)-1H-pyrazole-5-carboxylic acid | 3...)
Affinity DataIC50: 7.20E+5nMAssay Description:Inhibition of Pin1 by PIn1 PPIase assayMore data for this Ligand-Target Pair
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PubMed
LigandPNGBDBM50175430(5-(2-methoxyphenyl)furan-2-carboxylic acid | 5-(2-...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of Pin1 by PIn1 PPIase assayMore data for this Ligand-Target Pair
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PubMedPDB3D3D Structure (crystal)