Compile Data Set for Download or QSAR
Report error Found 109 Enz. Inhib. hit(s) with all data for entry = 50032472
TargetTGF-beta receptor type-1(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50329814((Z)-N-ethyl-3-((4-(N-methyl-2-(4-methylpiperazin-1...)
Affinity DataEC50:  2.18E+3nMAssay Description:Inhibition of TGFbeta receptor in human HaCaT cells assessed as Smad phosphorylation by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTGF-beta receptor type-1(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50329793((Z)-3-((4-(N-(2-(dimethylamino)ethyl)acetamido)phe...)
Affinity DataEC50:  1.07E+3nMAssay Description:Inhibition of TGFbeta receptor in human HaCaT cells assessed as Smad phosphorylation by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTGF-beta receptor type-1(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50329794((Z)-3-((4-(N-(2-(dimethylamino)ethyl)acetamido)phe...)
Affinity DataEC50:  102nMAssay Description:Inhibition of TGFbeta receptor in human HaCaT cells assessed as Smad phosphorylation by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTGF-beta receptor type-1(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50329800((Z)-3-((4-(2-(dimethylamino)-N-methylacetamido)phe...)
Affinity DataEC50:  3.38E+3nMAssay Description:Inhibition of TGFbeta receptor in human HaCaT cells assessed as Smad phosphorylation by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTGF-beta receptor type-1(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50329799((Z)-3-((4-((dimethylamino)methyl)phenylamino)(phen...)
Affinity DataEC50:  185nMAssay Description:Inhibition of TGFbeta receptor in human HaCaT cells assessed as Smad phosphorylation by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTGF-beta receptor type-1(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50329797((Z)-N-ethyl-3-((4-(N-methyl-2-(4-methylpiperazin-1...)
Affinity DataEC50:  1.37E+3nMAssay Description:Inhibition of TGFbeta receptor in human HaCaT cells assessed as Smad phosphorylation by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTGF-beta receptor type-1(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50329796((Z)-3-((4-(N-(3-(dimethylamino)propyl)acetamido)ph...)
Affinity DataEC50:  411nMAssay Description:Inhibition of TGFbeta receptor in human HaCaT cells assessed as Smad phosphorylation by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTGF-beta receptor type-1(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50329815((Z)-N-ethyl-2-oxo-3-((4-(piperidin-1-ylmethyl)phen...)
Affinity DataEC50:  376nMAssay Description:Inhibition of TGFbeta receptor in human HaCaT cells assessed as Smad phosphorylation by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTGF-beta receptor type-1(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50279163(CHEMBL496861 | CHEMBL1203981)
Affinity DataEC50:  246nMAssay Description:Inhibition of TGFbeta receptor in human HaCaT cells assessed as Smad phosphorylation by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTGF-beta receptor type-1(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50279164((3Z)-N-ETHYL-N-METHYL-2-OXO-3-(PHENYL{[4-(PIPERIDI...)
Affinity DataEC50:  105nMAssay Description:Inhibition of TGFbeta receptor in human HaCaT cells assessed as Smad phosphorylation by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetTGF-beta receptor type-1(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50329787((Z)-N-(2-hydroxyethyl)-2-oxo-3-(phenyl(4-(piperidi...)
Affinity DataEC50: >5.00E+4nMAssay Description:Inhibition of TGFbeta receptor in human HaCaT cells assessed as Smad phosphorylation by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTGF-beta receptor type-1(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50329792((Z)-3-((4-(N-(2-(dimethylamino)ethyl)methylsulfona...)
Affinity DataEC50:  209nMAssay Description:Inhibition of TGFbeta receptor in human HaCaT cells assessed as Smad phosphorylation by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTGF-beta receptor type-1(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50329795((Z)-3-((4-(N-(3-(dimethylamino)propyl)acetamido)ph...)
Affinity DataEC50:  1.25E+3nMAssay Description:Inhibition of TGFbeta receptor in human HaCaT cells assessed as Smad phosphorylation by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTGF-beta receptor type-1(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50279044((Z)-2-oxo-3-[Phenyl-(4-piperidin-1-ylmethyl-phenyl...)
Affinity DataEC50: >5.00E+4nMAssay Description:Inhibition of TGFbeta receptor in human HaCaT cells assessed as Smad phosphorylation by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTGF-beta receptor type-1(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50329784((Z)-3-[Phenyl-(4-piperidin-1-ylmethyl-phenylamino)...)
Affinity DataEC50:  75nMAssay Description:Inhibition of TGFbeta receptor in human HaCaT cells assessed as Smad phosphorylation by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTGF-beta receptor type-1(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50329785((Z)-N-butyl-2-oxo-3-(phenyl(4-(piperidin-1-ylmethy...)
Affinity DataEC50:  1.07E+3nMAssay Description:Inhibition of TGFbeta receptor in human HaCaT cells assessed as Smad phosphorylation by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTGF-beta receptor type-1(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50329786((Z)-3-(phenyl(4-(piperidin-1-ylmethyl)phenylamino)...)
Affinity DataEC50:  696nMAssay Description:Inhibition of TGFbeta receptor in human HaCaT cells assessed as Smad phosphorylation by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTGF-beta receptor type-1(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50279162((Z)-2-oxo-3-[Phenyl-(4-piperidin-1-ylmethyl-phenyl...)
Affinity DataEC50:  708nMAssay Description:Inhibition of TGFbeta receptor in human HaCaT cells assessed as Smad phosphorylation by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTGF-beta receptor type-1(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50329790((Z)-N,N-dimethyl-2-oxo-3-(phenyl(4-(piperidin-1-yl...)
Affinity DataEC50:  198nMAssay Description:Inhibition of TGFbeta receptor in human HaCaT cells assessed as Smad phosphorylation by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTGF-beta receptor type-1(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50110208(SB-431542 | cid_4521392 | 4-(5-(benzo[d][1,3]dioxo...)
Affinity DataEC50:  172nMAssay Description:Inhibition of TGFbeta receptor in human HaCaT cells assessed as Smad phosphorylation by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTGF-beta receptor type-1(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50329791((Z)-3-((4-(N-(2-(dimethylamino)ethyl)methylsulfona...)
Affinity DataEC50:  108nMAssay Description:Inhibition of TGFbeta receptor in human HaCaT cells assessed as Smad phosphorylation by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTGF-beta receptor type-1(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50329798((Z)-N-ethyl-N-methyl-3-((4-(N-methyl-2-(4-methylpi...)
Affinity DataEC50:  833nMAssay Description:Inhibition of TGFbeta receptor in human HaCaT cells assessed as Smad phosphorylation by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTGF-beta receptor type-1(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50329801((Z)-3-((4-(2-(dimethylamino)-N-methylacetamido)phe...)
Affinity DataEC50:  382nMAssay Description:Inhibition of TGFbeta receptor in human HaCaT cells assessed as Smad phosphorylation by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTGF-beta receptor type-1(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50329802((Z)-N-ethyl-3-((4-((ethylamino)methyl)phenylamino)...)
Affinity DataEC50:  160nMAssay Description:Inhibition of TGFbeta receptor in human HaCaT cells assessed as Smad phosphorylation by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTGF-beta receptor type-1(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50329803((Z)-3-((4-(2-(diethylamino)ethylcarbamoyl)phenylam...)
Affinity DataEC50:  505nMAssay Description:Inhibition of TGFbeta receptor in human HaCaT cells assessed as Smad phosphorylation by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTGF-beta receptor type-1(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50329804((Z)-3-((4-(2-(diethylamino)ethylcarbamoyl)phenylam...)
Affinity DataEC50:  542nMAssay Description:Inhibition of TGFbeta receptor in human HaCaT cells assessed as Smad phosphorylation by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTGF-beta receptor type-1(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50329805((Z)-3-((4-(2-(dimethylamino)ethyl)phenylamino)(phe...)
Affinity DataEC50:  135nMAssay Description:Inhibition of TGFbeta receptor in human HaCaT cells assessed as Smad phosphorylation by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTGF-beta receptor type-1(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50329806((Z)-3-((4-(2-(dimethylamino)ethyl)phenylamino)(phe...)
Affinity DataEC50:  259nMAssay Description:Inhibition of TGFbeta receptor in human HaCaT cells assessed as Smad phosphorylation by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTGF-beta receptor type-1(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50329807((Z)-3-((4-(N-(2-(dimethylamino)-2-oxoethyl)methyls...)
Affinity DataEC50: >3.00E+3nMAssay Description:Inhibition of TGFbeta receptor in human HaCaT cells assessed as Smad phosphorylation by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTGF-beta receptor type-1(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50329808((Z)-N-ethyl-N-methyl-3-((4-(N-methylmethylsulfonam...)
Affinity DataEC50: >1.00E+4nMAssay Description:Inhibition of TGFbeta receptor in human HaCaT cells assessed as Smad phosphorylation by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTGF-beta receptor type-1(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50329813((Z)-3-((4-(N-(3-(dimethylamino)propyl)acetamido)ph...)
Affinity DataEC50:  597nMAssay Description:Inhibition of TGFbeta receptor in human HaCaT cells assessed as Smad phosphorylation by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTGF-beta receptor type-1(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50329816((Z)-3-((4-(2-(dimethylamino)-N-methylacetamido)phe...)
Affinity DataEC50:  4.36E+3nMAssay Description:Inhibition of TGFbeta receptor in human HaCaT cells assessed as Smad phosphorylation by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTGF-beta receptor type-1(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50329817((Z)-N-ethyl-N-methyl-3-((1-methylpiperidin-4-ylami...)
Affinity DataEC50: >1.00E+4nMAssay Description:Inhibition of TGFbeta receptor in human HaCaT cells assessed as Smad phosphorylation by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTGF-beta receptor type-1(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50329818((Z)-3-((cyclohexylamino)(phenyl)methylene)-N-ethyl...)
Affinity DataEC50: >1.00E+4nMAssay Description:Inhibition of TGFbeta receptor in human HaCaT cells assessed as Smad phosphorylation by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTGF-beta receptor type-1(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50329791((Z)-3-((4-(N-(2-(dimethylamino)ethyl)methylsulfona...)
Affinity DataIC50: 1nMAssay Description:Inhibition of TGFbeta receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTGF-beta receptor type-1(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50329793((Z)-3-((4-(N-(2-(dimethylamino)ethyl)acetamido)phe...)
Affinity DataIC50: 3nMAssay Description:Inhibition of TGFbeta receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTGF-beta receptor type-1(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50329795((Z)-3-((4-(N-(3-(dimethylamino)propyl)acetamido)ph...)
Affinity DataIC50: 3nMAssay Description:Inhibition of TGFbeta receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTGF-beta receptor type-1(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50329798((Z)-N-ethyl-N-methyl-3-((4-(N-methyl-2-(4-methylpi...)
Affinity DataIC50: 7nMAssay Description:Inhibition of TGFbeta receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTGF-beta receptor type-1(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50329792((Z)-3-((4-(N-(2-(dimethylamino)ethyl)methylsulfona...)
Affinity DataIC50: 7nMAssay Description:Inhibition of TGFbeta receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTGF-beta receptor type-1(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50329794((Z)-3-((4-(N-(2-(dimethylamino)ethyl)acetamido)phe...)
Affinity DataIC50: 8nMAssay Description:Inhibition of TGFbeta receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTGF-beta receptor type-1(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50329796((Z)-3-((4-(N-(3-(dimethylamino)propyl)acetamido)ph...)
Affinity DataIC50: 9nMAssay Description:Inhibition of TGFbeta receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTGF-beta receptor type-1(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50329797((Z)-N-ethyl-3-((4-(N-methyl-2-(4-methylpiperazin-1...)
Affinity DataIC50: 9nMAssay Description:Inhibition of TGFbeta receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTGF-beta receptor type-1(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50329814((Z)-N-ethyl-3-((4-(N-methyl-2-(4-methylpiperazin-1...)
Affinity DataIC50: 15nMAssay Description:Inhibition of TGFbeta receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTGF-beta receptor type-1(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50329813((Z)-3-((4-(N-(3-(dimethylamino)propyl)acetamido)ph...)
Affinity DataIC50: 17nMAssay Description:Inhibition of TGFbeta receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTGF-beta receptor type-1(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50329799((Z)-3-((4-((dimethylamino)methyl)phenylamino)(phen...)
Affinity DataIC50: 19nMAssay Description:Inhibition of TGFbeta receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTGF-beta receptor type-1(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50329784((Z)-3-[Phenyl-(4-piperidin-1-ylmethyl-phenylamino)...)
Affinity DataIC50: 24nMAssay Description:Inhibition of TGFbeta receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTGF-beta receptor type-1(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50329801((Z)-3-((4-(2-(dimethylamino)-N-methylacetamido)phe...)
Affinity DataIC50: 29nMAssay Description:Inhibition of TGFbeta receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTGF-beta receptor type-1(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50329802((Z)-N-ethyl-3-((4-((ethylamino)methyl)phenylamino)...)
Affinity DataIC50: 32nMAssay Description:Inhibition of TGFbeta receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTGF-beta receptor type-1(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50279165(CHEMBL1203982 | CHEMBL497724)
Affinity DataIC50: 32nMAssay Description:Inhibition of TGFbeta receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTGF-beta receptor type-1(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50329803((Z)-3-((4-(2-(diethylamino)ethylcarbamoyl)phenylam...)
Affinity DataIC50: 33nMAssay Description:Inhibition of TGFbeta receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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