Compile Data Set for Download or QSAR
Report error Found 16 Enz. Inhib. hit(s) with all data for entry = 50032451
TargetProteinase-activated receptor 2(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50329483(2-Furoyl-Cha-Ile-NH2 | CHEMBL1271235)
Affinity DataEC50: >5.00E+4nMAssay Description:Agonist activity at human PAR2 receptor in HEK293 cells assessed as induction of intracellular calcium releaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProteinase-activated receptor 2(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50329484(2-Pyrazoyl-Cha-Ile-NH2 | CHEMBL1270927)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at human PAR2 receptor in HEK293 cells assessed as induction of intracellular calcium releaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProteinase-activated receptor 2(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50329485(5-Isoxazoyl-Cha-Ile-NH2 | CHEMBL1270823)
Affinity DataEC50: >4.00E+3nMAssay Description:Agonist activity at human PAR2 receptor in HEK293 cells assessed as induction of intracellular calcium releaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProteinase-activated receptor 2(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50329486(4-(2-Methyloxazoyl)-Cha-Ile-NH2 | CHEMBL1271236)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at human PAR2 receptor in HEK293 cells assessed as induction of intracellular calcium releaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProteinase-activated receptor 2(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50329488(5-Isoxazoyl-Cha-Ile-(3-[aminomethyl]phenyl)-(4-[am...)
Affinity DataEC50:  251nMAssay Description:Agonist activity at PAR2 receptor in human HT-29 cells assessed as induction of intracellular calcium releaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProteinase-activated receptor 2(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50329489(5-Isoxazoyl-Cha-Ile-(piperidin-3-yl)-(4-[aminometh...)
Affinity DataEC50:  1.26E+4nMAssay Description:Agonist activity at PAR2 receptor in human HT-29 cells assessed as induction of intracellular calcium releaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProteinase-activated receptor 2(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50329490(5-Isoxazoyl-Cha-Ile-(4-aminophenyl)-(4-[aminomethy...)
Affinity DataEC50: >5.00E+4nMAssay Description:Agonist activity at PAR2 receptor in human HT-29 cells assessed as induction of intracellular calcium releaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProteinase-activated receptor 2(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50329491(5-Isoxazoyl-Cha-Ile-4-aminophenyl-(4-[aminomethyl]...)
Affinity DataEC50:  316nMAssay Description:Agonist activity at PAR2 receptor in human HT-29 cells assessed as induction of intracellular calcium releaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProteinase-activated receptor 2(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50329492(5-Isoxazoyl-Cha-Ile-(4-[aminomethyl]phenyl)-(4-[am...)
Affinity DataEC50:  1.00E+3nMAssay Description:Agonist activity at PAR2 receptor in human HT-29 cells assessed as induction of intracellular calcium releaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProteinase-activated receptor 2(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50329493(5-Isoxazoyl-Cha-Ile-(piperidin-4-yl)-(4-[aminometh...)
Affinity DataEC50:  1.71E+4nMAssay Description:Agonist activity at PAR2 receptor in human HT-29 cells assessed as induction of intracellular calcium releaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProteinase-activated receptor 2(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50329494(5-isoxazoyl-Cha-Ile-(3-aminophenyl)-(4-[aminomethy...)
Affinity DataEC50:  2.00E+3nMAssay Description:Agonist activity at PAR2 receptor in human HT-29 cells assessed as induction of intracellular calcium releaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProteinase-activated receptor 2(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50329495(5-Isoxazoyl-Cha-Ile-(piperidin-2-yl)-(4-[aminometh...)
Affinity DataEC50:  7.94E+3nMAssay Description:Agonist activity at PAR2 receptor in human HT-29 cells assessed as induction of intracellular calcium releaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProteinase-activated receptor 2(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50329496(5-Isoxazoyl-Cha-Ile-(3R,6S)-6-amino-3-(4-[aminomet...)
Affinity DataEC50:  6.31E+3nMAssay Description:Agonist activity at PAR2 receptor in human HT-29 cells assessed as induction of intracellular calcium releaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProteinase-activated receptor 2(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50329497(5-Isoxazoyl-Cha-Ile-(R)-3-amino-1-([S]-1-[4-(amino...)
Affinity DataEC50:  1.26E+4nMAssay Description:Agonist activity at PAR2 receptor in human HT-29 cells assessed as induction of intracellular calcium releaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProteinase-activated receptor 2(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50417178(CHEMBL1270720)
Affinity DataIC50: 7.94E+3nMAssay Description:Antagonist activity at PAR2 receptor in human HT-29 cells assessed as inhibition of intracellular calcium releaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProteinase-activated receptor 2(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50329487(5-Isoxazoyl-Cha-Ile-4-aminophenyl-(4morpholin-1-yl...)
Affinity DataIC50: 5.70E+4nMAssay Description:Antagonist activity at PAR2 receptor in human HT-29 cells assessed as inhibition of intracellular calcium releaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed