Compile Data Set for Download or QSAR
Report error Found 26 Enz. Inhib. hit(s) with all data for entry = 50032437
TargetInterleukin-1 receptor-associated kinase 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50329198(CHEMBL1650533 | 2-{ethyl[(5-{[6-methyl-3-(1H-pyraz...)
Affinity DataIC50: 8nMAssay Description:Inhibition of IRK4More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50329197(3-((R)-1-((2S,6R)-2,6-dimethylmorpholino)ethyl)-N-...)
Affinity DataIC50: 10nMAssay Description:Inhibition of cMETMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50329197(3-((R)-1-((2S,6R)-2,6-dimethylmorpholino)ethyl)-N-...)
Affinity DataIC50: 10nMAssay Description:Inhibition of JAK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50329197(3-((R)-1-((2S,6R)-2,6-dimethylmorpholino)ethyl)-N-...)
Affinity DataIC50: 10nMAssay Description:Inhibition of IKK-betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50329197(3-((R)-1-((2S,6R)-2,6-dimethylmorpholino)ethyl)-N-...)
Affinity DataIC50: 10nMAssay Description:Inhibition of ERK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50329197(3-((R)-1-((2S,6R)-2,6-dimethylmorpholino)ethyl)-N-...)
Affinity DataIC50: 10nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetCasein kinase I isoform delta(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50329197(3-((R)-1-((2S,6R)-2,6-dimethylmorpholino)ethyl)-N-...)
Affinity DataIC50: 10nMAssay Description:Inhibition of CSNK1dMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50329197(3-((R)-1-((2S,6R)-2,6-dimethylmorpholino)ethyl)-N-...)
Affinity DataIC50: 10nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetCalcium/calmodulin-dependent protein kinase type IV(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50329197(3-((R)-1-((2S,6R)-2,6-dimethylmorpholino)ethyl)-N-...)
Affinity DataIC50: 10nMAssay Description:Inhibition of Camk4More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50329197(3-((R)-1-((2S,6R)-2,6-dimethylmorpholino)ethyl)-N-...)
Affinity DataIC50: 10nMAssay Description:Inhibition of AKT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK3(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50329197(3-((R)-1-((2S,6R)-2,6-dimethylmorpholino)ethyl)-N-...)
Affinity DataIC50: 10nMAssay Description:Inhibition of PLK3More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetTestis-specific serine/threonine-protein kinase 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50329197(3-((R)-1-((2S,6R)-2,6-dimethylmorpholino)ethyl)-N-...)
Affinity DataIC50: 10nMAssay Description:Inhibition of TSSK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetProtein kinase C alpha type(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50329197(3-((R)-1-((2S,6R)-2,6-dimethylmorpholino)ethyl)-N-...)
Affinity DataIC50: 10nMAssay Description:Inhibition of PKCalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50329197(3-((R)-1-((2S,6R)-2,6-dimethylmorpholino)ethyl)-N-...)
Affinity DataIC50: 10nMAssay Description:Inhibition of ROCK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50329198(CHEMBL1650533 | 2-{ethyl[(5-{[6-methyl-3-(1H-pyraz...)
Affinity DataIC50: 13nMAssay Description:Inhibition of CHK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50329196(3-(1-((2S,6R)-2,6-dimethylmorpholino)cyclopropyl)-...)
Affinity DataIC50: 45nMAssay Description:Inhibition of Aurora AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50329201(3-((2,2-dimethylpiperidin-1-yl)methyl)-N-(6-methyl...)
Affinity DataIC50: 45nMAssay Description:Inhibition of LCKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50329196(3-(1-((2S,6R)-2,6-dimethylmorpholino)cyclopropyl)-...)
Affinity DataIC50: 50nMAssay Description:Inhibition of Aurora BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50329197(3-((R)-1-((2S,6R)-2,6-dimethylmorpholino)ethyl)-N-...)
Affinity DataIC50: 140nMAssay Description:Inhibition of CHK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase alpha-3(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50329198(CHEMBL1650533 | 2-{ethyl[(5-{[6-methyl-3-(1H-pyraz...)
Affinity DataIC50: 180nMAssay Description:Inhibition of RSK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase alpha-3(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50329197(3-((R)-1-((2S,6R)-2,6-dimethylmorpholino)ethyl)-N-...)
Affinity DataIC50: 330nMAssay Description:Inhibition of RSK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50329200(3-((3,3-dimethylmorpholino)methyl)-N-(6-methyl-3-(...)
Affinity DataIC50: 384nMAssay Description:Inhibition of LCKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50329197(3-((R)-1-((2S,6R)-2,6-dimethylmorpholino)ethyl)-N-...)
Affinity DataIC50: 510nMAssay Description:Inhibition of LCKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50329199(3-methyl-N-(6-methyl-3-(1H-pyrazol-4-yl)imidazo[1,...)
Affinity DataIC50: 568nMAssay Description:Inhibition of LCKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50329197(3-((R)-1-((2S,6R)-2,6-dimethylmorpholino)ethyl)-N-...)
Affinity DataIC50: 710nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50329197(3-((R)-1-((2S,6R)-2,6-dimethylmorpholino)ethyl)-N-...)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of IRK4More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed