Compile Data Set for Download or QSAR
Report error Found 24 Enz. Inhib. hit(s) with all data for entry = 50041854
TargetEstrogen receptor beta(Human)
Charles University In Prague

Curated by ChEMBL
LigandPNGBDBM50417029(CHEMBL1257168)
Affinity DataEC50:  5.19E+3nMAssay Description:Agonist activity at ERbeta-LBD in human U2OS cells transfected with Gal4-DBD assessed as increase of transactivation activity after 18 hrs by lucifer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Charles University In Prague

Curated by ChEMBL
LigandPNGBDBM50417022(CHEMBL1258783)
Affinity DataEC50:  9.95E+3nMAssay Description:Agonist activity at ERalpha-LBD in human U2OS cells transfected with Gal4-DBD assessed as increase of transactivation activity after 18 hrs by lucife...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Charles University In Prague

Curated by ChEMBL
LigandPNGBDBM17292([2,4,6,7-3H]-17beta-estradiol | [3H]-estradiol | 1...)
Affinity DataEC50:  2.77nMAssay Description:Agonist activity at ERalpha-LBD in human U2OS cells transfected with Gal4-DBD assessed as increase of transactivation activity after 18 hrs by lucife...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Charles University In Prague

Curated by ChEMBL
LigandPNGBDBM17292([2,4,6,7-3H]-17beta-estradiol | [3H]-estradiol | 1...)
Affinity DataEC50:  0.458nMAssay Description:Agonist activity at ERbeta-LBD in human U2OS cells transfected with Gal4-DBD assessed as increase of transactivation activity after 18 hrs by lucifer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Charles University In Prague

Curated by ChEMBL
LigandPNGBDBM50417028(CHEMBL1258902)
Affinity DataEC50:  485nMAssay Description:Agonist activity at ERalpha-LBD in human U2OS cells transfected with Gal4-DBD assessed as increase of transactivation activity after 18 hrs by lucife...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Charles University In Prague

Curated by ChEMBL
LigandPNGBDBM50417030(CHEMBL1257167)
Affinity DataEC50:  403nMAssay Description:Agonist activity at ERalpha-LBD in human U2OS cells transfected with Gal4-DBD assessed as increase of transactivation activity after 18 hrs by lucife...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Charles University In Prague

Curated by ChEMBL
LigandPNGBDBM50417023(CHEMBL1258901)
Affinity DataEC50:  35.5nMAssay Description:Agonist activity at ERalpha-LBD in human U2OS cells transfected with Gal4-DBD assessed as increase of transactivation activity after 18 hrs by lucife...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Charles University In Prague

Curated by ChEMBL
LigandPNGBDBM50417027(CHEMBL1256103)
Affinity DataEC50:  1.03E+3nMAssay Description:Agonist activity at ERalpha-LBD in human U2OS cells transfected with Gal4-DBD assessed as increase of transactivation activity after 18 hrs by lucife...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Charles University In Prague

Curated by ChEMBL
LigandPNGBDBM50417028(CHEMBL1258902)
Affinity DataEC50:  2.40E+3nMAssay Description:Agonist activity at ERbeta-LBD in human U2OS cells transfected with Gal4-DBD assessed as increase of transactivation activity after 18 hrs by lucifer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Charles University In Prague

Curated by ChEMBL
LigandPNGBDBM50417027(CHEMBL1256103)
Affinity DataEC50:  52nMAssay Description:Agonist activity at ERbeta-LBD in human U2OS cells transfected with Gal4-DBD assessed as increase of transactivation activity after 18 hrs by lucifer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Charles University In Prague

Curated by ChEMBL
LigandPNGBDBM50417023(CHEMBL1258901)
Affinity DataEC50:  129nMAssay Description:Agonist activity at ERbeta-LBD in human U2OS cells transfected with Gal4-DBD assessed as increase of transactivation activity after 18 hrs by lucifer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Charles University In Prague

Curated by ChEMBL
LigandPNGBDBM50417026(CHEMBL1256105)
Affinity DataEC50:  6.73nMAssay Description:Agonist activity at glucocorticoid receptor-LBD in human U2OS cells transfected with Gal4-DBD assessed as increase of transactivation activity after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Charles University In Prague

Curated by ChEMBL
LigandPNGBDBM50417025(CHEMBL1257284)
Affinity DataEC50:  1.66E+3nMAssay Description:Agonist activity at ERalpha-LBD in human U2OS cells transfected with Gal4-DBD assessed as increase of transactivation activity after 18 hrs by lucife...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetMineralocorticoid receptor(Human)
Charles University In Prague

Curated by ChEMBL
LigandPNGBDBM19214([3H]Aldosterone | (1S,2R,10S,11S,14S,15R,17S)-17-h...)
Affinity DataEC50:  0.338nMAssay Description:Agonist activity at mineralocorticoid receptor-LBD in human U2OS cells transfected with Gal4-DBD assessed as increase of transactivation activity aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Charles University In Prague

Curated by ChEMBL
LigandPNGBDBM50417024(CHEMBL1256102)
Affinity DataEC50:  2.08E+3nMAssay Description:Agonist activity at ERalpha-LBD in human U2OS cells transfected with Gal4-DBD assessed as increase of transactivation activity after 18 hrs by lucife...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Charles University In Prague

Curated by ChEMBL
LigandPNGBDBM50417029(CHEMBL1257168)
Affinity DataEC50:  4.03E+3nMAssay Description:Agonist activity at ERalpha-LBD in human U2OS cells transfected with Gal4-DBD assessed as increase of transactivation activity after 18 hrs by lucife...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Charles University In Prague

Curated by ChEMBL
LigandPNGBDBM18207(dexamethasone (tetramethyl-rhodamine conjugated ) ...)
Affinity DataIC50: 0.508nMAssay Description:Antagonist activity at glucocorticoid receptor-LBD in human U2OS cells transfected with Gal4-DBD assessed as inhibition of transactivation activity a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetMineralocorticoid receptor(Human)
Charles University In Prague

Curated by ChEMBL
LigandPNGBDBM19214([3H]Aldosterone | (1S,2R,10S,11S,14S,15R,17S)-17-h...)
Affinity DataIC50: 9.27nMAssay Description:Antagonist activity at mineralocorticoid receptor-LBD in human U2OS cells transfected with Gal4-DBD assessed as inhibition of transactivation activit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Charles University In Prague

Curated by ChEMBL
LigandPNGBDBM17292([2,4,6,7-3H]-17beta-estradiol | [3H]-estradiol | 1...)
Affinity DataIC50: 10.7nMAssay Description:Antagonist activity at ERbeta-LBD in human U2OS cells transfected with Gal4-DBD assessed as inhibition of transactivation activity after 18 hrs by lu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Charles University In Prague

Curated by ChEMBL
LigandPNGBDBM17292([2,4,6,7-3H]-17beta-estradiol | [3H]-estradiol | 1...)
Affinity DataIC50: 21.0nMAssay Description:Antagonist activity at ERalpha-LBD in human U2OS cells transfected with Gal4-DBD assessed as inhibition of transactivation activity after 18 hrs by l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Charles University In Prague

Curated by ChEMBL
LigandPNGBDBM50417023(CHEMBL1258901)
Affinity DataIC50: 3.13E+3nMAssay Description:Antagonist activity at glucocorticoid receptor-LBD in human U2OS cells transfected with Gal4-DBD assessed as inhibition of transactivation activity a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetMineralocorticoid receptor(Human)
Charles University In Prague

Curated by ChEMBL
LigandPNGBDBM50417023(CHEMBL1258901)
Affinity DataIC50: 3.81E+3nMAssay Description:Antagonist activity at mineralocorticoid receptor-LBD in human U2OS cells transfected with Gal4-DBD assessed as inhibition of transactivation activit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetMineralocorticoid receptor(Human)
Charles University In Prague

Curated by ChEMBL
LigandPNGBDBM50417030(CHEMBL1257167)
Affinity DataIC50: 5.14E+3nMAssay Description:Antagonist activity at mineralocorticoid receptor-LBD in human U2OS cells transfected with Gal4-DBD assessed as inhibition of transactivation activit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Charles University In Prague

Curated by ChEMBL
LigandPNGBDBM50417022(CHEMBL1258783)
Affinity DataIC50: 1.36E+4nMAssay Description:Antagonist activity at glucocorticoid receptor-LBD in human U2OS cells transfected with Gal4-DBD assessed as inhibition of transactivation activity a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed