Compile Data Set for Download or QSAR
Report error Found 12 Enz. Inhib. hit(s) with all data for entry = 3582
TargetFarnesyl pyrophosphate synthase(Human)
Novartis Institutes For Biomedical Research

LigandPNGBDBM36511(CID46398842 | 5-((2-Carboxy-1H-benzo[g]indol-1-yl)...)
Affinity DataIC50: 80nMpH: 7.4 T: 2°CAssay Description:A biophysical assay using NMR spectroscopy to identify fragments with higher binding affinity to human recombinant FPPS.More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2011
Entry Details Article
PubMed
TargetFarnesyl pyrophosphate synthase(Human)
Novartis Institutes For Biomedical Research

LigandPNGBDBM36510(CID46398840 | 1-(Carboxymethyl)-1H-benzo[g]indole-...)
Affinity DataIC50: 200nMpH: 7.4 T: 2°CAssay Description:A biophysical assay using NMR spectroscopy to identify fragments with higher binding affinity to human recombinant FPPS.More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetFarnesyl pyrophosphate synthase(Human)
Novartis Institutes For Biomedical Research

LigandPNGBDBM36508(CID46398841 | 3-(Carboxymethyl)-4,7-dichloro-1H-in...)
Affinity DataIC50: 2.00E+3nMpH: 7.4 T: 2°CAssay Description:A biophysical assay using NMR spectroscopy to identify fragments with higher binding affinity to human recombinant FPPS.More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2011
Entry Details Article
PubMed
TargetFarnesyl pyrophosphate synthase(Human)
Novartis Institutes For Biomedical Research

LigandPNGBDBM36509(CID46398845 | 3-(Carboxymethyl)-5,7-dichloro-1H-in...)
Affinity DataIC50: 6.00E+3nMpH: 7.4 T: 2°CAssay Description:A biophysical assay using NMR spectroscopy to identify fragments with higher binding affinity to human recombinant FPPS.More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2011
Entry Details Article
PubMed
TargetFarnesyl pyrophosphate synthase(Human)
Novartis Institutes For Biomedical Research

LigandPNGBDBM36506(CID46398844 | 2-(Naphtho[2,1-b]thiophen-1-yl)aceti...)
Affinity DataIC50: 7.00E+3nMpH: 7.4 T: 2°CAssay Description:A biophysical assay using NMR spectroscopy to identify fragments with higher binding affinity to human recombinant FPPS.More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetFarnesyl pyrophosphate synthase(Human)
Novartis Institutes For Biomedical Research

LigandPNGBDBM36505(CID46398839 | 2-(3-Chlorobenzo[b]thiophen-2-yl)ace...)
Affinity DataIC50: 1.20E+4nMpH: 7.4 T: 2°CAssay Description:A biophysical assay using NMR spectroscopy to identify fragments with higher binding affinity to human recombinant FPPS.More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2011
Entry Details Article
PubMed
TargetFarnesyl pyrophosphate synthase(Human)
Novartis Institutes For Biomedical Research

LigandPNGBDBM36507(CID6932062 | (R)-1-(benzyloxycarbonyl)indoline-2-c...)
Affinity DataIC50: 5.00E+4nMpH: 7.4 T: 2°CAssay Description:A biophysical assay using NMR spectroscopy to identify fragments with higher binding affinity to human recombinant FPPS.More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetFarnesyl pyrophosphate synthase(Human)
Novartis Institutes For Biomedical Research

LigandPNGBDBM36504(CID46398843 | 2-(4-Chlorobenzo[b]thiophen-2-yl)pro...)
Affinity DataIC50: 8.00E+4nMpH: 7.4 T: 2°CAssay Description:A biophysical assay using NMR spectroscopy to identify fragments with higher binding affinity to human recombinant FPPS.More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2011
Entry Details Article
PubMed
TargetFarnesyl pyrophosphate synthase(Human)
Novartis Institutes For Biomedical Research

LigandPNGBDBM36500(CID205058 | 2-(5-Chlorobenzo[b]thiophen-3-yl)aceti...)
Affinity DataIC50: 5.00E+5nMpH: 7.4 T: 2°CAssay Description:A biophysical assay using NMR spectroscopy to identify fragments with higher binding affinity to human recombinant FPPS.More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetFarnesyl pyrophosphate synthase(Human)
Novartis Institutes For Biomedical Research

LigandPNGBDBM36501(CID68686 | 2-(5-chloro-3-methylbenzo[b]thiophen-2-...)
Affinity DataIC50: 5.00E+5nMpH: 7.4 T: 2°CAssay Description:A biophysical assay using NMR spectroscopy to identify fragments with higher binding affinity to human recombinant FPPS.More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetFarnesyl pyrophosphate synthase(Human)
Novartis Institutes For Biomedical Research

LigandPNGBDBM36502(CID736818 | 2-(6-Methoxybenzofuran-3-yl)acetic aci...)
Affinity DataIC50: 5.00E+5nMpH: 7.4 T: 2°CAssay Description:A biophysical assay using NMR spectroscopy to identify fragments with higher binding affinity to human recombinant FPPS.More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetFarnesyl pyrophosphate synthase(Human)
Novartis Institutes For Biomedical Research

LigandPNGBDBM36503(CID6932064 | (S)-1-((Benzyloxy)carbonyl)indoline-2...)
Affinity DataIC50: 5.00E+5nMpH: 7.4 T: 2°CAssay Description:A biophysical assay using NMR spectroscopy to identify fragments with higher binding affinity to human recombinant FPPS.More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2011
Entry Details Article
PubMed