Compile Data Set for Download or QSAR
Report error Found 69 Enz. Inhib. hit(s) with all data for entry = 50032193
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50325788(2-(4-((8-(3-(difluoromethoxy)phenyl)quinolin-6-yl)...)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of human PDE4DMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50325790(methyl 2-(4-((8-(3-methoxyphenyl)quinolin-6-yl)met...)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of human PDE4DMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50174022(L-454560 | 8-(3-methoxyphenyl)-6-(pyridin-4-ylmeth...)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of human PDE4BMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50325786(4-(4-((8-(3-(difluoromethoxy)phenyl)quinolin-6-yl)...)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of human PDE4DMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50325787(8-(3-(difluoromethoxy)phenyl)-6-((4-(methylsulfony...)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of human PDE4DMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50325800(3-(4-((8-(3-(difluoromethoxy)phenyl)quinolin-6-yl)...)
Affinity DataIC50: 0.900nMAssay Description:Inhibition of human PDE4DMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50174022(L-454560 | 8-(3-methoxyphenyl)-6-(pyridin-4-ylmeth...)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of human PDE4DMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50174022(L-454560 | 8-(3-methoxyphenyl)-6-(pyridin-4-ylmeth...)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of human PDE4AMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50174017(8-(3-methoxyphenyl)-6-(pyridin-4-ylmethyl)quinolin...)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of human PDE4AMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50325794(3-(4-((8-(3-methoxyphenyl)quinolin-6-yl)methoxy)ph...)
Affinity DataIC50: 2nMAssay Description:Inhibition of human PDE4DMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50174017(8-(3-methoxyphenyl)-6-(pyridin-4-ylmethyl)quinolin...)
Affinity DataIC50: 2.30nMAssay Description:Inhibition of human PDE4BMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50174017(8-(3-methoxyphenyl)-6-(pyridin-4-ylmethyl)quinolin...)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of human PDE4DMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50174017(8-(3-methoxyphenyl)-6-(pyridin-4-ylmethyl)quinolin...)
Affinity DataIC50: 3.30nMAssay Description:Inhibition of human PDE4CMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50325798(3-(4-((8-(3-ethoxyphenyl)quinolin-6-yl)methoxy)phe...)
Affinity DataIC50: 4.5nMAssay Description:Inhibition of human PDE4DMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50325790(methyl 2-(4-((8-(3-methoxyphenyl)quinolin-6-yl)met...)
Affinity DataIC50: 4.60nMAssay Description:Inhibition of human PDE4AMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50325791(6-((2-chlorophenoxy)methyl)-8-(3-methoxyphenyl)qui...)
Affinity DataIC50: 5nMAssay Description:Inhibition of human PDE4DMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50325788(2-(4-((8-(3-(difluoromethoxy)phenyl)quinolin-6-yl)...)
Affinity DataIC50: 5.70nMAssay Description:Inhibition of human PDE4AMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50325790(methyl 2-(4-((8-(3-methoxyphenyl)quinolin-6-yl)met...)
Affinity DataIC50: 7.40nMAssay Description:Inhibition of human PDE4BMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50325788(2-(4-((8-(3-(difluoromethoxy)phenyl)quinolin-6-yl)...)
Affinity DataIC50: 8.70nMAssay Description:Inhibition of human PDE4BMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50174022(L-454560 | 8-(3-methoxyphenyl)-6-(pyridin-4-ylmeth...)
Affinity DataIC50: 9.10nMAssay Description:Inhibition of human PDE4CMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50325789(8-(3-methoxyphenyl)-6-(2-(methylsulfonyl)propan-2-...)
Affinity DataIC50: 9.30nMAssay Description:Inhibition of human PDE4DMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50325789(8-(3-methoxyphenyl)-6-(2-(methylsulfonyl)propan-2-...)
Affinity DataIC50: 9.90nMAssay Description:Inhibition of human PDE4AMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50325797(3-(4-((8-(3-fluorophenyl)quinolin-6-yl)methoxy)phe...)
Affinity DataIC50: 11nMAssay Description:Inhibition of human PDE4DMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50325789(8-(3-methoxyphenyl)-6-(2-(methylsulfonyl)propan-2-...)
Affinity DataIC50: 11nMAssay Description:Inhibition of human PDE4BMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50325792(6-((3-chlorophenoxy)methyl)-8-(3-methoxyphenyl)qui...)
Affinity DataIC50: 12nMAssay Description:Inhibition of human PDE4DMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50325787(8-(3-(difluoromethoxy)phenyl)-6-((4-(methylsulfony...)
Affinity DataIC50: 13nMAssay Description:Inhibition of human PDE4AMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50325787(8-(3-(difluoromethoxy)phenyl)-6-((4-(methylsulfony...)
Affinity DataIC50: 15nMAssay Description:Inhibition of human PDE4BMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50325796(3-(4-((8-(3-(trifluoromethoxy)phenyl)quinolin-6-yl...)
Affinity DataIC50: 17nMAssay Description:Inhibition of human PDE4DMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50325799(3-(4-((8-m-tolylquinolin-6-yl)methoxy)phenyl)propa...)
Affinity DataIC50: 18nMAssay Description:Inhibition of human PDE4DMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50325795(3-(4-((8-phenylquinolin-6-yl)methoxy)phenyl)propan...)
Affinity DataIC50: 22nMAssay Description:Inhibition of human PDE4DMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50325790(methyl 2-(4-((8-(3-methoxyphenyl)quinolin-6-yl)met...)
Affinity DataIC50: 31nMAssay Description:Inhibition of human PDE4CMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50325788(2-(4-((8-(3-(difluoromethoxy)phenyl)quinolin-6-yl)...)
Affinity DataIC50: 32nMAssay Description:Inhibition of human PDE4CMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50325787(8-(3-(difluoromethoxy)phenyl)-6-((4-(methylsulfony...)
Affinity DataIC50: 36nMAssay Description:Inhibition of human PDE4CMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50325798(3-(4-((8-(3-ethoxyphenyl)quinolin-6-yl)methoxy)phe...)
Affinity DataIC50: 43nMAssay Description:Inhibition of human PDE4BMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50325786(4-(4-((8-(3-(difluoromethoxy)phenyl)quinolin-6-yl)...)
Affinity DataIC50: 45nMAssay Description:Inhibition of human PDE4BMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50325793(8-(3-methoxyphenyl)-6-((4-(trifluoromethyl)phenoxy...)
Affinity DataIC50: 49nMAssay Description:Inhibition of human PDE4DMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50325800(3-(4-((8-(3-(difluoromethoxy)phenyl)quinolin-6-yl)...)
Affinity DataIC50: 58nMAssay Description:Inhibition of human PDE4BMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50325800(3-(4-((8-(3-(difluoromethoxy)phenyl)quinolin-6-yl)...)
Affinity DataIC50: 60nMAssay Description:Inhibition of human PDE4AMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50325786(4-(4-((8-(3-(difluoromethoxy)phenyl)quinolin-6-yl)...)
Affinity DataIC50: 64nMAssay Description:Inhibition of human PDE4AMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50325789(8-(3-methoxyphenyl)-6-(2-(methylsulfonyl)propan-2-...)
Affinity DataIC50: 70nMAssay Description:Inhibition of human PDE4CMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50325794(3-(4-((8-(3-methoxyphenyl)quinolin-6-yl)methoxy)ph...)
Affinity DataIC50: 87nMAssay Description:Inhibition of human PDE4BMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50325791(6-((2-chlorophenoxy)methyl)-8-(3-methoxyphenyl)qui...)
Affinity DataIC50: 87nMAssay Description:Inhibition of human PDE4BMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50325797(3-(4-((8-(3-fluorophenyl)quinolin-6-yl)methoxy)phe...)
Affinity DataIC50: 93nMAssay Description:Inhibition of human PDE4BMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50325796(3-(4-((8-(3-(trifluoromethoxy)phenyl)quinolin-6-yl...)
Affinity DataIC50: 96nMAssay Description:Inhibition of human PDE4BMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50325792(6-((3-chlorophenoxy)methyl)-8-(3-methoxyphenyl)qui...)
Affinity DataIC50: 102nMAssay Description:Inhibition of human PDE4CMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50325800(3-(4-((8-(3-(difluoromethoxy)phenyl)quinolin-6-yl)...)
Affinity DataIC50: 103nMAssay Description:Inhibition of human PDE4CMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50325795(3-(4-((8-phenylquinolin-6-yl)methoxy)phenyl)propan...)
Affinity DataIC50: 120nMAssay Description:Inhibition of human PDE4BMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50325794(3-(4-((8-(3-methoxyphenyl)quinolin-6-yl)methoxy)ph...)
Affinity DataIC50: 122nMAssay Description:Inhibition of human PDE4AMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50325791(6-((2-chlorophenoxy)methyl)-8-(3-methoxyphenyl)qui...)
Affinity DataIC50: 126nMAssay Description:Inhibition of human PDE4AMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50325786(4-(4-((8-(3-(difluoromethoxy)phenyl)quinolin-6-yl)...)
Affinity DataIC50: 151nMAssay Description:Inhibition of human PDE4CMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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