Compile Data Set for Download or QSAR
Report error Found 13 Enz. Inhib. hit(s) with all data for entry = 50032189
TargetC-C chemokine receptor type 1(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50325723((R)-2-(4-(4-chlorobenzyl)-5-methyl-4H-1,2,4-triazo...)
Affinity DataIC50: 2.90nMAssay Description:Antagonist activity at CCR1 in human THP1 cells assessed as inhibition of CCL3-induced chemotaxis after 3 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetC-C chemokine receptor type 1(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50325722((R)-2-(4-(4-chlorobenzyl)-4H-1,2,4-triazol-3-yl)-N...)
Affinity DataIC50: 4nMAssay Description:Antagonist activity at CCR1 in human THP1 cells assessed as inhibition of CCL3-induced chemotaxis after 3 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetC-C chemokine receptor type 1(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50325719((R)-2-(1-(4-chlorobenzyl)-1H-tetrazol-5-yl)-N-(4-(...)
Affinity DataIC50: 6.5nMAssay Description:Antagonist activity at CCR1 in human THP1 cells assessed as inhibition of CCL3-induced chemotaxis after 3 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetC-C chemokine receptor type 1(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50325718(2-(1-(4-chlorobenzyl)-1H-imidazol-2-yl)-N-(4-(trif...)
Affinity DataIC50: 16nMAssay Description:Antagonist activity at CCR1 in human THP1 cells assessed as inhibition of CCL3-induced chemotaxis after 3 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetC-C chemokine receptor type 1(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50325722((R)-2-(4-(4-chlorobenzyl)-4H-1,2,4-triazol-3-yl)-N...)
Affinity DataIC50: 17nMAssay Description:Displacement of [125I]-MIP1-alpha from human recombinant CCR1 expressed in HEK293 cells after 4 hrs by SPAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetC-C chemokine receptor type 1(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50325719((R)-2-(1-(4-chlorobenzyl)-1H-tetrazol-5-yl)-N-(4-(...)
Affinity DataIC50: 20nMAssay Description:Displacement of [125I]-MIP1-alpha from human recombinant CCR1 expressed in HEK293 cells after 4 hrs by SPAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetC-C chemokine receptor type 1(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50293051((R)-N2-(4-Chlorobenzyl)-N2-methyl-N1-[4-(trifluoro...)
Affinity DataIC50: 22nMAssay Description:Antagonist activity at CCR1 in human THP1 cells assessed as inhibition of CCL3-induced chemotaxis after 3 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetC-C chemokine receptor type 1(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50325720((R)-2-(1-(4-chlorobenzyl)-1H-1,2,4-triazol-5-yl)-N...)
Affinity DataIC50: 22nMAssay Description:Antagonist activity at CCR1 in human THP1 cells assessed as inhibition of CCL3-induced chemotaxis after 3 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetC-C chemokine receptor type 1(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50325720((R)-2-(1-(4-chlorobenzyl)-1H-1,2,4-triazol-5-yl)-N...)
Affinity DataIC50: 32nMAssay Description:Displacement of [125I]-MIP1-alpha from human recombinant CCR1 expressed in HEK293 cells after 4 hrs by SPAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetC-C chemokine receptor type 1(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50325718(2-(1-(4-chlorobenzyl)-1H-imidazol-2-yl)-N-(4-(trif...)
Affinity DataIC50: 65nMAssay Description:Displacement of [125I]-MIP1-alpha from human recombinant CCR1 expressed in HEK293 cells after 4 hrs by SPAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetC-C chemokine receptor type 1(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50325723((R)-2-(4-(4-chlorobenzyl)-5-methyl-4H-1,2,4-triazo...)
Affinity DataIC50: 69nMAssay Description:Displacement of [125I]-MIP1-alpha from human recombinant CCR1 expressed in HEK293 cells after 4 hrs by SPAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetC-C chemokine receptor type 1(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50293051((R)-N2-(4-Chlorobenzyl)-N2-methyl-N1-[4-(trifluoro...)
Affinity DataIC50: 140nMAssay Description:Displacement of [125I]-MIP1-alpha from human recombinant CCR1 expressed in HEK293 cells after 4 hrs by SPAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetC-C chemokine receptor type 1(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50325721((R)-2-(1-(4-chlorobenzyl)-3-methyl-1H-1,2,4-triazo...)
Affinity DataIC50: 810nMAssay Description:Displacement of [125I]-MIP1-alpha from human recombinant CCR1 expressed in HEK293 cells after 4 hrs by SPAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed