Compile Data Set for Download or QSAR
Report error Found 61 Enz. Inhib. hit(s) with all data for entry = 50032095
TargetAurora kinase A(Human)
Development Center For Biotechnology

Curated by ChEMBL
LigandPNGBDBM50324264((Z)-3-(4-Oxo-2-{[2-oxo-5-(pyrrolidin-1-ylsulfonyl)...)
Affinity DataIC50: 7nMAssay Description:Inhibition of recombinant aurora AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Development Center For Biotechnology

Curated by ChEMBL
LigandPNGBDBM50324267((Z)-3-(2-{[5-(Indolin-1-ylsulfonyl)-2-oxoindolin-3...)
Affinity DataIC50: 8nMAssay Description:Inhibition of recombinant aurora AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Development Center For Biotechnology

Curated by ChEMBL
LigandPNGBDBM50324269((Z)-3-(4-Oxo-2-{[2-oxo-5-(phenylsulfonamido)indoli...)
Affinity DataIC50: 12nMAssay Description:Inhibition of recombinant aurora AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Development Center For Biotechnology

Curated by ChEMBL
LigandPNGBDBM50324265((Z)-3-(4-Oxo-2-{[2-oxo-5-(piperidin-1-ylsulfonyl)i...)
Affinity DataIC50: 14nMAssay Description:Inhibition of recombinant aurora AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Development Center For Biotechnology

Curated by ChEMBL
LigandPNGBDBM50324263((Z)-3-(2-{[5-(N,N-Dimethylsulfamoyl)-2-oxoindolin-...)
Affinity DataIC50: 21nMAssay Description:Inhibition of recombinant aurora AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Development Center For Biotechnology

Curated by ChEMBL
LigandPNGBDBM50324266((Z)-3-(2-{[5-(Morpholinosulfonyl)-2-oxoindolin-3-y...)
Affinity DataIC50: 29nMAssay Description:Inhibition of recombinant aurora AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Development Center For Biotechnology

Curated by ChEMBL
LigandPNGBDBM50324262((Z)-3-(2-{[5-(N-Methylsulfamoyl)-2-oxoindolin-3-yl...)
Affinity DataIC50: 31nMAssay Description:Inhibition of recombinant aurora AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Development Center For Biotechnology

Curated by ChEMBL
LigandPNGBDBM50324268((Z)-3-(2-{[5-(Ethylsulfonamido)-2-oxoindolin-3-yli...)
Affinity DataIC50: 34nMAssay Description:Inhibition of recombinant aurora AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Development Center For Biotechnology

Curated by ChEMBL
LigandPNGBDBM50324258((Z)-3-(2-{[5-(Allylsulfonyl)-2-oxoindolin-3-yliden...)
Affinity DataIC50: 39nMAssay Description:Inhibition of recombinant aurora AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Development Center For Biotechnology

Curated by ChEMBL
LigandPNGBDBM50324257((Z)-3-(2-{[5-(Ethylsulfonyl)-2-oxoindolin-3-yliden...)
Affinity DataIC50: 57nMAssay Description:Inhibition of recombinant aurora AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Development Center For Biotechnology

Curated by ChEMBL
LigandPNGBDBM50324261((Z)-3-{4-Oxo-2-[(2-oxo-5-sulfamoylindolin-3-yliden...)
Affinity DataIC50: 61nMAssay Description:Inhibition of recombinant aurora AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Development Center For Biotechnology

Curated by ChEMBL
LigandPNGBDBM50324270((Z)-3-(4-Oxo-2-{[2-oxo-5-(phenylmethylsulfonamido)...)
Affinity DataIC50: 63nMAssay Description:Inhibition of recombinant aurora AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Development Center For Biotechnology

Curated by ChEMBL
LigandPNGBDBM50324271((Z)-Ethyl 3-(4-Oxo-2-{[2-oxo-5-(phenylsulfonamido)...)
Affinity DataIC50: 84nMAssay Description:Inhibition of recombinant aurora AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Development Center For Biotechnology

Curated by ChEMBL
LigandPNGBDBM50324274((Z)-N-Methyl-3-(4-oxo-2-{[2-oxo-5-(phenylsulfonami...)
Affinity DataIC50: 117nMAssay Description:Inhibition of recombinant aurora AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Development Center For Biotechnology

Curated by ChEMBL
LigandPNGBDBM50324269((Z)-3-(4-Oxo-2-{[2-oxo-5-(phenylsulfonamido)indoli...)
Affinity DataIC50: 156nMAssay Description:Inhibition of recombinant aurora BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Development Center For Biotechnology

Curated by ChEMBL
LigandPNGBDBM50324284((Z)-3-{2-[(5-Fluoro-2-oxoindolin-3-ylidene)methyl]...)
Affinity DataIC50: 178nMAssay Description:Inhibition of recombinant aurora AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Development Center For Biotechnology

Curated by ChEMBL
LigandPNGBDBM50324283((Z)-3-{4-Oxo-2-[(2-oxoindolin-3-ylidene)methyl]-4,...)
Affinity DataIC50: 208nMAssay Description:Inhibition of recombinant aurora AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Development Center For Biotechnology

Curated by ChEMBL
LigandPNGBDBM50324251((Z)-3-{2-[(5-Bromo-2-oxoindolin-3-ylidene)methyl]-...)
Affinity DataIC50: 210nMAssay Description:Inhibition of recombinant aurora AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Development Center For Biotechnology

Curated by ChEMBL
LigandPNGBDBM50324271((Z)-Ethyl 3-(4-Oxo-2-{[2-oxo-5-(phenylsulfonamido)...)
Affinity DataIC50: 214nMAssay Description:Inhibition of recombinant aurora BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Development Center For Biotechnology

Curated by ChEMBL
LigandPNGBDBM50324272((Z)-N-[2-Oxo-3-({4-oxo-3-[3-oxo-3-(pyrrolidin-1-yl...)
Affinity DataIC50: 218nMAssay Description:Inhibition of recombinant aurora AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Development Center For Biotechnology

Curated by ChEMBL
LigandPNGBDBM50324277((Z)-N-[3-({3-[3-(Dimethylamino)propyl]-4-oxo-4,5,6...)
Affinity DataIC50: 235nMAssay Description:Inhibition of recombinant aurora BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Development Center For Biotechnology

Curated by ChEMBL
LigandPNGBDBM50324255((Z)-3-{2-[(5-Acetamido-2-oxoindolin-3-ylidene)meth...)
Affinity DataIC50: 252nMAssay Description:Inhibition of recombinant aurora AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Development Center For Biotechnology

Curated by ChEMBL
LigandPNGBDBM50324259((Z)-3-(2-{[5-(Benzylsulfonyl)-2-oxoindolin-3-ylide...)
Affinity DataIC50: 271nMAssay Description:Inhibition of recombinant aurora AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Development Center For Biotechnology

Curated by ChEMBL
LigandPNGBDBM50324273((Z)-N-(3-{[3-(3-Morpholino-3-oxopropyl)-4-oxo-4,5,...)
Affinity DataIC50: 281nMAssay Description:Inhibition of recombinant aurora AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Development Center For Biotechnology

Curated by ChEMBL
LigandPNGBDBM50324267((Z)-3-(2-{[5-(Indolin-1-ylsulfonyl)-2-oxoindolin-3...)
Affinity DataIC50: 292nMAssay Description:Inhibition of recombinant aurora BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Development Center For Biotechnology

Curated by ChEMBL
LigandPNGBDBM50324276((Z)-N-[2-Oxo-3-({4-oxo-3-[3-(pyrrolidin-1-yl)propy...)
Affinity DataIC50: 310nMAssay Description:Inhibition of recombinant aurora BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Development Center For Biotechnology

Curated by ChEMBL
LigandPNGBDBM50324279((Z)-3-({3-[3-(Dimethylamino)propyl]-4-oxo-4,5,6,7-...)
Affinity DataIC50: 312nMAssay Description:Inhibition of recombinant aurora BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Development Center For Biotechnology

Curated by ChEMBL
LigandPNGBDBM50324274((Z)-N-Methyl-3-(4-oxo-2-{[2-oxo-5-(phenylsulfonami...)
Affinity DataIC50: 320nMAssay Description:Inhibition of recombinant aurora BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Development Center For Biotechnology

Curated by ChEMBL
LigandPNGBDBM50324278((Z)-N-[3-({3-[3-(Diethylamino)propyl]-4-oxo-4,5,6,...)
Affinity DataIC50: 356nMAssay Description:Inhibition of recombinant aurora BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Development Center For Biotechnology

Curated by ChEMBL
LigandPNGBDBM50324253((Z)-3-(2-{[5-(4-Hydroxy-3-methoxyphenyl)-2-oxoindo...)
Affinity DataIC50: 357nMAssay Description:Inhibition of recombinant aurora AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Development Center For Biotechnology

Curated by ChEMBL
LigandPNGBDBM50324250((Z)-3-{4-Acetyl-2-[(5-fluoro-2-oxoindolin-3-yliden...)
Affinity DataIC50: 362nMAssay Description:Inhibition of recombinant aurora AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Development Center For Biotechnology

Curated by ChEMBL
LigandPNGBDBM50324270((Z)-3-(4-Oxo-2-{[2-oxo-5-(phenylmethylsulfonamido)...)
Affinity DataIC50: 402nMAssay Description:Inhibition of recombinant aurora BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Development Center For Biotechnology

Curated by ChEMBL
LigandPNGBDBM50324264((Z)-3-(4-Oxo-2-{[2-oxo-5-(pyrrolidin-1-ylsulfonyl)...)
Affinity DataIC50: 441nMAssay Description:Inhibition of recombinant aurora BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Development Center For Biotechnology

Curated by ChEMBL
LigandPNGBDBM50324260((Z)-3-(2-{[5-(4-Fluorobenzylsulfonyl)-2-oxoindolin...)
Affinity DataIC50: 443nMAssay Description:Inhibition of recombinant aurora AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Development Center For Biotechnology

Curated by ChEMBL
LigandPNGBDBM50324285((Z)-3-{2-[(5-Fluoro-2-oxoindolin-3-ylidene)methyl]...)
Affinity DataIC50: 456nMAssay Description:Inhibition of recombinant aurora AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Development Center For Biotechnology

Curated by ChEMBL
LigandPNGBDBM50324265((Z)-3-(4-Oxo-2-{[2-oxo-5-(piperidin-1-ylsulfonyl)i...)
Affinity DataIC50: 495nMAssay Description:Inhibition of recombinant aurora BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Development Center For Biotechnology

Curated by ChEMBL
LigandPNGBDBM50324254((Z)-3-(2-{[5-(3,4-Dimethoxyphenyl)-2-oxoindolin-3-...)
Affinity DataIC50: 560nMAssay Description:Inhibition of recombinant aurora AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Development Center For Biotechnology

Curated by ChEMBL
LigandPNGBDBM50324275((Z)-5-(Indolin-1-ylsulfonyl)-3-{[3-(3-morpholino-3...)
Affinity DataIC50: 563nMAssay Description:Inhibition of recombinant aurora AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Development Center For Biotechnology

Curated by ChEMBL
LigandPNGBDBM50324280((Z)-3-({3-[3-(Diethylamino)propyl]-4-oxo-4,5,6,7-t...)
Affinity DataIC50: 616nMAssay Description:Inhibition of recombinant aurora BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Development Center For Biotechnology

Curated by ChEMBL
LigandPNGBDBM50324272((Z)-N-[2-Oxo-3-({4-oxo-3-[3-oxo-3-(pyrrolidin-1-yl...)
Affinity DataIC50: 719nMAssay Description:Inhibition of recombinant aurora BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Development Center For Biotechnology

Curated by ChEMBL
LigandPNGBDBM50324256((Z)-3-{2-[(5-Benzamido-2-oxoindolin-3-ylidene)meth...)
Affinity DataIC50: 720nMAssay Description:Inhibition of recombinant aurora AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Development Center For Biotechnology

Curated by ChEMBL
LigandPNGBDBM50324252((Z)-3-{2-[(5-Nitro-2-oxoindolin-3-ylidene)methyl]-...)
Affinity DataIC50: 724nMAssay Description:Inhibition of recombinant aurora AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Development Center For Biotechnology

Curated by ChEMBL
LigandPNGBDBM50324273((Z)-N-(3-{[3-(3-Morpholino-3-oxopropyl)-4-oxo-4,5,...)
Affinity DataIC50: 906nMAssay Description:Inhibition of recombinant aurora BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Development Center For Biotechnology

Curated by ChEMBL
LigandPNGBDBM50324277((Z)-N-[3-({3-[3-(Dimethylamino)propyl]-4-oxo-4,5,6...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of CSF1R by radiometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Development Center For Biotechnology

Curated by ChEMBL
LigandPNGBDBM50324271((Z)-Ethyl 3-(4-Oxo-2-{[2-oxo-5-(phenylsulfonamido)...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of c-Kit by radiometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Development Center For Biotechnology

Curated by ChEMBL
LigandPNGBDBM50324271((Z)-Ethyl 3-(4-Oxo-2-{[2-oxo-5-(phenylsulfonamido)...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of PDGFRbeta by radiometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Development Center For Biotechnology

Curated by ChEMBL
LigandPNGBDBM50324277((Z)-N-[3-({3-[3-(Dimethylamino)propyl]-4-oxo-4,5,6...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of FLT3 by radiometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Development Center For Biotechnology

Curated by ChEMBL
LigandPNGBDBM50324277((Z)-N-[3-({3-[3-(Dimethylamino)propyl]-4-oxo-4,5,6...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of PDGFRbeta by radiometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Development Center For Biotechnology

Curated by ChEMBL
LigandPNGBDBM50324277((Z)-N-[3-({3-[3-(Dimethylamino)propyl]-4-oxo-4,5,6...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of VEGFR2 by radiometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Development Center For Biotechnology

Curated by ChEMBL
LigandPNGBDBM50324271((Z)-Ethyl 3-(4-Oxo-2-{[2-oxo-5-(phenylsulfonamido)...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of CSF1R by radiometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
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