Compile Data Set for Download or QSAR
Report error Found 28 Enz. Inhib. hit(s) with all data for entry = 50001054
TargetThymidylate synthase(Escherichia coli)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50008294(2-{4-[(2-Amino-4-oxo-3,4-dihydro-quinazolin-6-ylme...)
Affinity DataKi:  3nMAssay Description:Inhibition of Thymidylate synthase of Escherichia coli (Ki)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidylate synthase(Escherichia coli)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50012244(CHEMBL25889 | 2-{4-[(2-Methyl-4-oxo-3,4-dihydro-qu...)
Affinity DataKi:  4.80nMAssay Description:Inhibition of Thymidylate synthase of Escherichia coli (Ki)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidylate synthase(Human)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50012244(CHEMBL25889 | 2-{4-[(2-Methyl-4-oxo-3,4-dihydro-qu...)
Affinity DataKi:  8.5nMAssay Description:Inhibition of human Thymidylate synthase (Ki)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidylate synthase(Human)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50008294(2-{4-[(2-Amino-4-oxo-3,4-dihydro-quinazolin-6-ylme...)
Affinity DataKi:  12nMAssay Description:Inhibition of human Thymidylate synthase (Ki)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidylate synthase(Human)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50011244(CHEMBL417222 | 6-{[(4-Benzenesulfonyl-phenyl)-prop...)
Affinity DataKi:  13nMAssay Description:Inhibition of human Thymidylate synthase (Ki)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidylate synthase(Escherichia coli)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50011244(CHEMBL417222 | 6-{[(4-Benzenesulfonyl-phenyl)-prop...)
Affinity DataKi:  25nMAssay Description:Inhibition of Thymidylate synthase of Escherichia coli (Ki)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidylate synthase(Human)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50005330(5-(4-Benzenesulfonyl-benzyl)-5,6,7,8-tetrahydro-1H...)
Affinity DataKi:  31nMAssay Description:Inhibition of human Thymidylate synthase (Ki)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidylate synthase(Human)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50005203(CHEMBL275685 | (4-Benzenesulfonyl-benzyl)-(2-imino...)
Affinity DataKi:  31nMAssay Description:Inhibition of human Thymidylate synthase (Ki)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidylate synthase(Escherichia coli)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50012245(CHEMBL291548 | 6-{[(4-Benzenesulfonyl-3-trifluorom...)
Affinity DataKi:  37nMAssay Description:Inhibition of Thymidylate synthase of Escherichia coli (Ki)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidylate synthase(Escherichia coli)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50005330(5-(4-Benzenesulfonyl-benzyl)-5,6,7,8-tetrahydro-1H...)
Affinity DataKi:  43nMAssay Description:Inhibition of Thymidylate synthase of Escherichia coli (Ki)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidylate synthase(Human)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50012245(CHEMBL291548 | 6-{[(4-Benzenesulfonyl-3-trifluorom...)
Affinity DataKi:  50nMAssay Description:Inhibition of human Thymidylate synthase (Ki)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidylate synthase(Human)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50005323(5-[4-(Piperazine-1-sulfonyl)-benzyl]-5,6,7,8-tetra...)
Affinity DataKi:  64nMAssay Description:Inhibition of human Thymidylate synthase (Ki)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidylate synthase(Human)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50012240(CHEMBL299928 | 6-({[4-(Indole-1-sulfonyl)-phenyl]-...)
Affinity DataKi:  69nMAssay Description:Inhibition of human Thymidylate synthase (Ki)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidylate synthase(Escherichia coli)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50005323(5-[4-(Piperazine-1-sulfonyl)-benzyl]-5,6,7,8-tetra...)
Affinity DataKi:  140nMAssay Description:Inhibition of Thymidylate synthase of Escherichia coli (Ki)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidylate synthase(Escherichia coli)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50012240(CHEMBL299928 | 6-({[4-(Indole-1-sulfonyl)-phenyl]-...)
Affinity DataKi:  150nMAssay Description:Inhibition of Thymidylate synthase of Escherichia coli (Ki)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidylate synthase(Human)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50012243(CHEMBL301423 | 2-Methyl-6-{[prop-2-ynyl-(3-trifluo...)
Affinity DataKi:  390nMAssay Description:Inhibition of human Thymidylate synthase (Ki)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidylate synthase(Escherichia coli)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50012243(CHEMBL301423 | 2-Methyl-6-{[prop-2-ynyl-(3-trifluo...)
Affinity DataKi:  450nMAssay Description:Inhibition of Thymidylate synthase of Escherichia coli (Ki)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidylate synthase(Human)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50005202(CHEMBL301844 | 6-[(4-Benzenesulfonyl-benzyl)-methy...)
Affinity DataKi:  770nMAssay Description:Inhibition of human Thymidylate synthase (Ki)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidylate synthase(Human)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50005183(1-Methyl-6-{methyl-[4-(piperazine-1-sulfonyl)-benz...)
Affinity DataKi:  840nMAssay Description:Inhibition of human Thymidylate synthase (Ki)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidylate synthase(Escherichia coli)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50005202(CHEMBL301844 | 6-[(4-Benzenesulfonyl-benzyl)-methy...)
Affinity DataKi: >1.00E+3nMAssay Description:Inhibition of Thymidylate synthase of Escherichia coli (Ki)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidylate synthase(Escherichia coli)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50005203(CHEMBL275685 | (4-Benzenesulfonyl-benzyl)-(2-imino...)
Affinity DataKi:  1.50E+3nMAssay Description:Inhibition of Thymidylate synthase of Escherichia coli (Ki)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidylate synthase(Human)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50012242(CHEMBL57333 | 2-Methyl-6-[(phenyl-prop-2-ynyl-amin...)
Affinity DataKi:  2.20E+3nMAssay Description:Inhibition of human Thymidylate synthase (Ki)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidylate synthase(Human)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50012241(CHEMBL56992 | 4-(4-{[Ethyl-(2-oxo-1,2-dihydro-benz...)
Affinity DataKi:  3.00E+3nMAssay Description:Inhibition of human Thymidylate synthase (Ki)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidylate synthase(Escherichia coli)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50012242(CHEMBL57333 | 2-Methyl-6-[(phenyl-prop-2-ynyl-amin...)
Affinity DataKi:  4.00E+3nMAssay Description:Inhibition of Thymidylate synthase of Escherichia coli (Ki)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidylate synthase(Escherichia coli)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50005328(CHEMBL353700 | 5-[4-(Piperazine-1-sulfonyl)-benzyl...)
Affinity DataKi:  4.90E+3nMAssay Description:Inhibition of Thymidylate synthase of Escherichia coli (Ki)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidylate synthase(Human)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50005328(CHEMBL353700 | 5-[4-(Piperazine-1-sulfonyl)-benzyl...)
Affinity DataKi:  7.70E+3nMAssay Description:Inhibition of human Thymidylate synthase (Ki)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidylate synthase(Escherichia coli)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50005183(1-Methyl-6-{methyl-[4-(piperazine-1-sulfonyl)-benz...)
Affinity DataKi:  2.10E+4nMAssay Description:Inhibition of Thymidylate synthase of Escherichia coli (Ki)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidylate synthase(Escherichia coli)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50012241(CHEMBL56992 | 4-(4-{[Ethyl-(2-oxo-1,2-dihydro-benz...)
Affinity DataKi:  3.80E+4nMAssay Description:Inhibition of Thymidylate synthase of Escherichia coli (Ki)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed