Compile Data Set for Download or QSAR
Report error Found 23 Enz. Inhib. hit(s) with all data for entry = 50032158
TargetMetabotropic glutamate receptor 4(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50325115(N-(4-(N-(2-chlorophenyl)sulfamoyl)phenyl)-6-fluoro...)
Affinity DataEC50:  122nMAssay Description:Positive allosteric modulation of human mGlu4 receptor expressed in CHO cells assessed as potentiation of glutamate-induced calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50325126(N-(4-(N-mesitylsulfamoyl)phenyl)furan-2-carboxamid...)
Affinity DataEC50:  5.96E+3nMAssay Description:Positive allosteric modulation of human mGlu4 receptor expressed in CHO cells assessed as potentiation of glutamate-induced calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50325125(N-(4-(N-mesitylsulfamoyl)phenyl)picolinamide | VU0...)
Affinity DataEC50:  159nMAssay Description:Positive allosteric modulation of human mGlu4 receptor expressed in CHO cells assessed as potentiation of glutamate-induced calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50325124(N-(4-(N-phenylsulfamoyl)phenyl)picolinamide | CHEM...)
Affinity DataEC50:  177nMAssay Description:Positive allosteric modulation of human mGlu4 receptor expressed in CHO cells assessed as potentiation of glutamate-induced calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50325123(N-(4-(N-(2-chlorophenyl)sulfamoyl)phenyl)picolinam...)
Affinity DataEC50:  27nMAssay Description:Positive allosteric modulation of human mGlu4 receptor expressed in CHO cells assessed as potentiation of glutamate-induced calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50325122(N-(4-(N-(2-fluorophenyl)sulfamoyl)phenyl)picolinam...)
Affinity DataEC50:  206nMAssay Description:Positive allosteric modulation of human mGlu4 receptor expressed in CHO cells assessed as potentiation of glutamate-induced calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50325121(N-(4-(N-(2,5-difluorophenyl)sulfamoyl)phenyl)picol...)
Affinity DataEC50:  325nMAssay Description:Positive allosteric modulation of human mGlu4 receptor expressed in CHO cells assessed as potentiation of glutamate-induced calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50325120(N-(4-(N-cyclopropylsulfamoyl)phenyl)picolinamide |...)
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation of human mGlu4 receptor expressed in CHO cells assessed as potentiation of glutamate-induced calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50325119(N-(4-(N-cyclobutylsulfamoyl)phenyl)picolinamide | ...)
Affinity DataEC50: >5.00E+3nMAssay Description:Positive allosteric modulation of human mGlu4 receptor expressed in CHO cells assessed as potentiation of glutamate-induced calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50325118(N-(4-(N-(cyclopropylmethyl)sulfamoyl)phenyl)picoli...)
Affinity DataEC50: >5.00E+3nMAssay Description:Positive allosteric modulation of human mGlu4 receptor expressed in CHO cells assessed as potentiation of glutamate-induced calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50325117(N-(4-(N-(2-methoxyethyl)sulfamoyl)phenyl)picolinam...)
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation of human mGlu4 receptor expressed in CHO cells assessed as potentiation of glutamate-induced calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50325116(N-(4-(4-methylpiperidin-1-ylsulfonyl)phenyl)picoli...)
Affinity DataEC50:  372nMAssay Description:Positive allosteric modulation of human mGlu4 receptor expressed in CHO cells assessed as potentiation of glutamate-induced calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50325104(N-(4-(N-cyclohexylsulfamoyl)phenyl)picolinamide | ...)
Affinity DataEC50:  1.03E+3nMAssay Description:Positive allosteric modulation of human mGlu4 receptor expressed in CHO cells assessed as potentiation of glutamate-induced calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50325114(N-(4-(N-(2-chlorophenyl)sulfamoyl)phenyl)pyrimidin...)
Affinity DataEC50:  478nMAssay Description:Positive allosteric modulation of human mGlu4 receptor expressed in CHO cells assessed as potentiation of glutamate-induced calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50325113(N-(4-(N-(2-chlorophenyl)sulfamoyl)phenyl)thiazole-...)
Affinity DataEC50:  77.4nMAssay Description:Positive allosteric modulation of human mGlu4 receptor expressed in CHO cells assessed as potentiation of glutamate-induced calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50325112(N-(4-(N-(2-chlorophenyl)sulfamoyl)phenyl)thiophene...)
Affinity DataEC50:  269nMAssay Description:Positive allosteric modulation of human mGlu4 receptor expressed in CHO cells assessed as potentiation of glutamate-induced calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50325111(N-(4-(N-(2-chlorophenyl)-N-methylsulfamoyl)phenyl)...)
Affinity DataEC50:  990nMAssay Description:Positive allosteric modulation of human mGlu4 receptor expressed in CHO cells assessed as potentiation of glutamate-induced calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50325110(N-(4-(N-(2-chlorophenyl)-N-methylsulfamoyl)phenyl)...)
Affinity DataEC50:  686nMAssay Description:Positive allosteric modulation of human mGlu4 receptor expressed in CHO cells assessed as potentiation of glutamate-induced calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50325109(N-(3-methoxy-4-(N-(2-methoxyphenyl)sulfamoyl)pheny...)
Affinity DataEC50:  132nMAssay Description:Positive allosteric modulation of human mGlu4 receptor expressed in CHO cells assessed as potentiation of glutamate-induced calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50325108(N-(3-chloro-4-(N-(2-chlorophenyl)sulfamoyl)phenyl)...)
Affinity DataEC50:  19.8nMAssay Description:Positive allosteric modulation of human mGlu4 receptor expressed in CHO cells assessed as potentiation of glutamate-induced calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50325107(N-(4-chloro-3-(N-(2-chlorophenyl)sulfamoyl)phenyl)...)
Affinity DataEC50:  731nMAssay Description:Positive allosteric modulation of human mGlu4 receptor expressed in CHO cells assessed as potentiation of glutamate-induced calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50325106(N-(4-(2-chlorobenzylsulfonyl)phenyl)picolinamide |...)
Affinity DataEC50:  237nMAssay Description:Positive allosteric modulation of human mGlu4 receptor expressed in CHO cells assessed as potentiation of glutamate-induced calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50325105(N-(4-((2-chlorophenylsulfonyl)methyl)phenyl)picoli...)
Affinity DataEC50:  2.17E+3nMAssay Description:Positive allosteric modulation of human mGlu4 receptor expressed in CHO cells assessed as potentiation of glutamate-induced calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed