Compile Data Set for Download or QSAR
Report error Found 31 Enz. Inhib. hit(s) with all data for entry = 50032142
TargetIntegrin alpha-L(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50324825((R)-5-(4-bromobenzyl)-3-(3,5-dichlorophenyl)-5-met...)
Affinity DataKd:  26nMAssay Description:Binding affinity to LFA1More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetIntegrin alpha-L(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50324826((2S)-2-(2,6-dichloro-4-(3-hydroxy-3-(3-hydroxyphen...)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of LFA1 by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetIntegrin beta-2/Intercellular adhesion molecule 1(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50324824((S)-2-(2-(benzofuran-2-carbonyl)-5,7-dichloro-1,2,...)
Affinity DataIC50: 5nMAssay Description:Inhibition of LFA1/ICAM1 interaction in human Hut-78 cells by cell migration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetIntegrin beta-2/Intercellular adhesion molecule 1(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50324822((S)-2-(2-(benzofuran-6-carbonyl)-5,7-dichloro-1,2,...)
Affinity DataIC50: 9nMAssay Description:Inhibition of LFA1/ICAM1 interaction in human Hut-78 cells by cell migration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetIntegrin beta-2/Intercellular adhesion molecule 1(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50324810((S)-2-(5,7-dichloro-2-(4-methylbenzoyl)-1,2,3,4-te...)
Affinity DataIC50: 10nMAssay Description:Inhibition of LFA1/ICAM1 interaction in human Hut-78 cells by cell migration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetIntegrin beta-2/Intercellular adhesion molecule 1(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50324823((S)-2-(5,7-dichloro-2-(2,3-dihydrobenzofuran-6-car...)
Affinity DataIC50: 13nMAssay Description:Inhibition of LFA1/ICAM1 interaction in human Hut-78 cells by cell migration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetIntegrin beta-2/Intercellular adhesion molecule 1(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50324812((S)-2-(5,7-dichloro-2-(4-chlorobenzoyl)-1,2,3,4-te...)
Affinity DataIC50: 22nMAssay Description:Inhibition of LFA1/ICAM1 interaction in human Hut-78 cells by cell migration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetIntegrin beta-2/Intercellular adhesion molecule 1(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50324806((S,E)-2-(5,7-dichloro-2-(3-(furan-2-yl)acryloyl)-1...)
Affinity DataIC50: 25nMAssay Description:Inhibition of LFA1/ICAM1 interaction in human Hut-78 cells by cell migration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetIntegrin beta-2/Intercellular adhesion molecule 1(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50324816((S)-3-benzamido-2-(5,7-dichloro-2-(4-chlorobenzoyl...)
Affinity DataIC50: 29nMAssay Description:Inhibition of LFA1/ICAM1 interaction in human Hut-78 cells by cell migration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetIntegrin beta-2/Intercellular adhesion molecule 1(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50092956(A-286982 | 1-(4-acetylpiperazin-1-yl)-3-(4-(2-isop...)
Affinity DataIC50: 44nMAssay Description:Inhibition of LFA1/ICAM1 interaction in human Hut-78 cells by cell migration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetIntegrin beta-2/Intercellular adhesion molecule 1(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50324817((S)-2-(5,7-dichloro-2-(4-chlorobenzoyl)-1,2,3,4-te...)
Affinity DataIC50: 51nMAssay Description:Inhibition of LFA1/ICAM1 interaction in human Hut-78 cells by cell migration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetIntegrin beta-2/Intercellular adhesion molecule 1(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50324811((S)-2-(5,7-dichloro-2-(3-chlorobenzoyl)-1,2,3,4-te...)
Affinity DataIC50: 66nMAssay Description:Inhibition of LFA1/ICAM1 interaction in human Hut-78 cells by cell migration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetIntegrin alpha-L(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50324824((S)-2-(2-(benzofuran-2-carbonyl)-5,7-dichloro-1,2,...)
Affinity DataIC50: 69nMAssay Description:Inhibition of LFA1-mediated Staphylococcal enterotoxin B-stimulated human T cell activation in presence of 10% fetal bovine serumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetIntegrin beta-2/Intercellular adhesion molecule 1(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50324807((S)-2-(2-benzoyl-5,7-dichloro-1,2,3,4-tetrahydrois...)
Affinity DataIC50: 79nMAssay Description:Inhibition of LFA1/ICAM1 interaction in human Hut-78 cells by cell migration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetIntegrin beta-2/Intercellular adhesion molecule 1(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50324809((S)-2-(5,7-dichloro-2-(3-methylbenzoyl)-1,2,3,4-te...)
Affinity DataIC50: 90nMAssay Description:Inhibition of LFA1/ICAM1 interaction in human Hut-78 cells by cell migration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetIntegrin alpha-L(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50324811((S)-2-(5,7-dichloro-2-(3-chlorobenzoyl)-1,2,3,4-te...)
Affinity DataIC50: 240nMAssay Description:Inhibition of LFA1-mediated Staphylococcal enterotoxin B-stimulated human T cell activation in presence of 10% fetal bovine serumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetIntegrin alpha-L(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50324822((S)-2-(2-(benzofuran-6-carbonyl)-5,7-dichloro-1,2,...)
Affinity DataIC50: 260nMAssay Description:Inhibition of LFA1-mediated Staphylococcal enterotoxin B-stimulated human T cell activation in presence of 10% fetal bovine serumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetIntegrin alpha-L(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50324812((S)-2-(5,7-dichloro-2-(4-chlorobenzoyl)-1,2,3,4-te...)
Affinity DataIC50: 430nMAssay Description:Inhibition of LFA1-mediated Staphylococcal enterotoxin B-stimulated human T cell activation in presence of 10% fetal bovine serumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetIntegrin beta-2/Intercellular adhesion molecule 1(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50324808((S)-2-(5,7-dichloro-2-(2-methylbenzoyl)-1,2,3,4-te...)
Affinity DataIC50: 460nMAssay Description:Inhibition of LFA1/ICAM1 interaction in human Hut-78 cells by cell migration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetIntegrin beta-2/Intercellular adhesion molecule 1(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50324815((S)-3-(cyclohexanecarboxamido)-2-(5,7-dichloro-2-(...)
Affinity DataIC50: 540nMAssay Description:Inhibition of LFA1/ICAM1 interaction in human Hut-78 cells by cell migration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetIntegrin alpha-L(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50324816((S)-3-benzamido-2-(5,7-dichloro-2-(4-chlorobenzoyl...)
Affinity DataIC50: 550nMAssay Description:Inhibition of LFA1-mediated Staphylococcal enterotoxin B-stimulated human T cell activation in presence of 10% fetal bovine serumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetIntegrin beta-2/Intercellular adhesion molecule 1(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50324814((S)-3-acetamido-2-(5,7-dichloro-2-(4-chlorobenzoyl...)
Affinity DataIC50: 620nMAssay Description:Inhibition of LFA1/ICAM1 interaction in human Hut-78 cells by cell migration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetIntegrin alpha-L(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50324823((S)-2-(5,7-dichloro-2-(2,3-dihydrobenzofuran-6-car...)
Affinity DataIC50: 650nMAssay Description:Inhibition of LFA1-mediated Staphylococcal enterotoxin B-stimulated human T cell activation in presence of 10% fetal bovine serumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetIntegrin beta-2/Intercellular adhesion molecule 1(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50324819((S)-2-(5,7-dichloro-2-(4-chlorobenzoyl)-1,2,3,4-te...)
Affinity DataIC50: 810nMAssay Description:Inhibition of LFA1/ICAM1 interaction in human Hut-78 cells by cell migration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetIntegrin beta-2/Intercellular adhesion molecule 1(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50324821((S)-2-(5,7-dichloro-2-(cyclohexanecarbonyl)-1,2,3,...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of LFA1/ICAM1 interaction in human Hut-78 cells by cell migration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetIntegrin beta-2/Intercellular adhesion molecule 1(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50324813((S)-3-amino-2-(5,7-dichloro-2-(4-chlorobenzoyl)-1,...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of LFA1/ICAM1 interaction in human Hut-78 cells by cell migration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetIntegrin beta-2/Intercellular adhesion molecule 1(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50324818((S)-2-(5,7-dichloro-2-(4-chlorobenzoyl)-1,2,3,4-te...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of LFA1/ICAM1 interaction in human Hut-78 cells by cell migration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetIntegrin beta-2/Intercellular adhesion molecule 1(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50324820((S)-2-(2-acetyl-5,7-dichloro-1,2,3,4-tetrahydroiso...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of LFA1/ICAM1 interaction in human Hut-78 cells by cell migration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetIntegrin alpha-L(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50324807((S)-2-(2-benzoyl-5,7-dichloro-1,2,3,4-tetrahydrois...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of LFA1-mediated Staphylococcal enterotoxin B-stimulated human T cell activation in presence of 10% fetal bovine serumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetIntegrin alpha-L(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50324810((S)-2-(5,7-dichloro-2-(4-methylbenzoyl)-1,2,3,4-te...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of LFA1-mediated Staphylococcal enterotoxin B-stimulated human T cell activation in presence of 10% fetal bovine serumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetIntegrin alpha-L(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50324817((S)-2-(5,7-dichloro-2-(4-chlorobenzoyl)-1,2,3,4-te...)
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of LFA1-mediated Staphylococcal enterotoxin B-stimulated human T cell activation in presence of 10% fetal bovine serumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed