Compile Data Set for Download or QSAR
Report error Found 54 Enz. Inhib. hit(s) with all data for entry = 50032243
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Glenmark Research Center

Curated by ChEMBL
LigandPNGBDBM50326165(oxalylaminobenzoic acid | CHEMBL1241315)
Affinity DataIC50: 38nMAssay Description:Inhibition of human recombinant PTP1B after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Glenmark Research Center

Curated by ChEMBL
LigandPNGBDBM50296382((3S)-7-{4-[(3R)-1,2-Dithiolan-3-yl]butylcarboxamid...)
Affinity DataIC50: 51.6nMAssay Description:Inhibition of human recombinant PTP1B after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Glenmark Research Center

Curated by ChEMBL
LigandPNGBDBM50326155(8-{2-[4-(Pyrrolidin-1-yl)phenyl]thiazol-4-yl}diben...)
Affinity DataIC50: 82nMAssay Description:Inhibition of human recombinant PTP1B after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Glenmark Research Center

Curated by ChEMBL
LigandPNGBDBM50326156(8-{2-[4-(Piperidin-1-yl)phenyl]thiazol-4-yl}dibenz...)
Affinity DataIC50: 121nMAssay Description:Inhibition of human recombinant PTP1B after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Glenmark Research Center

Curated by ChEMBL
LigandPNGBDBM50326165(oxalylaminobenzoic acid | CHEMBL1241315)
Affinity DataIC50: 136nMAssay Description:Inhibition of human recombinant TCPTP after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Glenmark Research Center

Curated by ChEMBL
LigandPNGBDBM50326160(8-[2-(3,5-Dibromo-4-(1-carboxy-2-phenylethoxy)phen...)
Affinity DataIC50: 177nMAssay Description:Inhibition of human recombinant PTP1B after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Glenmark Research Center

Curated by ChEMBL
LigandPNGBDBM50326153(8-[2-(4-Aminophenyl)thiazol-4-yl]dibenzo[b,d]furan...)
Affinity DataIC50: 185nMAssay Description:Inhibition of human recombinant PTP1B after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Glenmark Research Center

Curated by ChEMBL
LigandPNGBDBM50326158(8-{2-[4-(2,6-Dimethylmorpholino)phenyl]thiazol-4-y...)
Affinity DataIC50: 187nMAssay Description:Inhibition of human recombinant PTP1B after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Glenmark Research Center

Curated by ChEMBL
LigandPNGBDBM50326152(8-[2-(4-Nitrophenyl)thiazol-4-yl]dibenzo[b,d]furan...)
Affinity DataIC50: 201nMAssay Description:Inhibition of human recombinant PTP1B after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Glenmark Research Center

Curated by ChEMBL
LigandPNGBDBM50326154(8-{2-[4-(Dimethylamino)phenyl]thiazol-4-yl}dibenzo...)
Affinity DataIC50: 257nMAssay Description:Inhibition of human recombinant PTP1B after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Glenmark Research Center

Curated by ChEMBL
LigandPNGBDBM50326157(8-[2-(4-Morpholinophenyl)thiazol-4-yl]dibenzo[b,d]...)
Affinity DataIC50: 280nMAssay Description:Inhibition of human recombinant PTP1B after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Glenmark Research Center

Curated by ChEMBL
LigandPNGBDBM50326152(8-[2-(4-Nitrophenyl)thiazol-4-yl]dibenzo[b,d]furan...)
Affinity DataIC50: 348nMAssay Description:Inhibition of human recombinant TCPTP after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Glenmark Research Center

Curated by ChEMBL
LigandPNGBDBM50326159(8-[2-(4-Carboxyphenyl)thiazol-4-yl]dibenzo[b,d]fur...)
Affinity DataIC50: 388nMAssay Description:Inhibition of human recombinant PTP1B after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Glenmark Research Center

Curated by ChEMBL
LigandPNGBDBM50326161(8-[2-(4-Iodophenyl)thiazol-4-yl]dibenzo[b,d]furan-...)
Affinity DataIC50: 395nMAssay Description:Inhibition of human recombinant PTP1B after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase F(Human)
Glenmark Research Center

Curated by ChEMBL
LigandPNGBDBM50326165(oxalylaminobenzoic acid | CHEMBL1241315)
Affinity DataIC50: 410nMAssay Description:Inhibition of human recombinant LAR after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Glenmark Research Center

Curated by ChEMBL
LigandPNGBDBM50326162(8-[2-(3-Iodophenyl)thiazol-4-yl]dibenzo[b,d]furan-...)
Affinity DataIC50: 425nMAssay Description:Inhibition of human recombinant PTP1B after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Glenmark Research Center

Curated by ChEMBL
LigandPNGBDBM50326151(8-(2-Methylthiazol-4-yl)dibenzo[b,d]furan-4-carbox...)
Affinity DataIC50: 515nMAssay Description:Inhibition of human recombinant PTP1B after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Glenmark Research Center

Curated by ChEMBL
LigandPNGBDBM50326164((E)-8-{2-[3-(2-Carboxyvinyl)phenyl]thiazol-4-yl}di...)
Affinity DataIC50: 551nMAssay Description:Inhibition of human recombinant PTP1B after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Glenmark Research Center

Curated by ChEMBL
LigandPNGBDBM50326163((E)-8-{2-[4-(2-Carboxyvinyl)phenyl]thiazol-4-yl}di...)
Affinity DataIC50: 620nMAssay Description:Inhibition of human recombinant PTP1B after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Glenmark Research Center

Curated by ChEMBL
LigandPNGBDBM50326153(8-[2-(4-Aminophenyl)thiazol-4-yl]dibenzo[b,d]furan...)
Affinity DataIC50: 693nMAssay Description:Inhibition of human recombinant TCPTP after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Glenmark Research Center

Curated by ChEMBL
LigandPNGBDBM50326151(8-(2-Methylthiazol-4-yl)dibenzo[b,d]furan-4-carbox...)
Affinity DataIC50: 730nMAssay Description:Inhibition of human recombinant TCPTP after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Glenmark Research Center

Curated by ChEMBL
LigandPNGBDBM50326164((E)-8-{2-[3-(2-Carboxyvinyl)phenyl]thiazol-4-yl}di...)
Affinity DataIC50: 794nMAssay Description:Inhibition of human recombinant TCPTP after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Glenmark Research Center

Curated by ChEMBL
LigandPNGBDBM50326154(8-{2-[4-(Dimethylamino)phenyl]thiazol-4-yl}dibenzo...)
Affinity DataIC50: 961nMAssay Description:Inhibition of human recombinant TCPTP after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Glenmark Research Center

Curated by ChEMBL
LigandPNGBDBM50326163((E)-8-{2-[4-(2-Carboxyvinyl)phenyl]thiazol-4-yl}di...)
Affinity DataIC50: 983nMAssay Description:Inhibition of human recombinant TCPTP after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase F(Human)
Glenmark Research Center

Curated by ChEMBL
LigandPNGBDBM50326151(8-(2-Methylthiazol-4-yl)dibenzo[b,d]furan-4-carbox...)
Affinity DataIC50: 1.32E+3nMAssay Description:Inhibition of human recombinant LAR after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Glenmark Research Center

Curated by ChEMBL
LigandPNGBDBM50326158(8-{2-[4-(2,6-Dimethylmorpholino)phenyl]thiazol-4-y...)
Affinity DataIC50: 1.43E+3nMAssay Description:Inhibition of human recombinant TCPTP after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Glenmark Research Center

Curated by ChEMBL
LigandPNGBDBM50326162(8-[2-(3-Iodophenyl)thiazol-4-yl]dibenzo[b,d]furan-...)
Affinity DataIC50: 1.62E+3nMAssay Description:Inhibition of human recombinant TCPTP after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Glenmark Research Center

Curated by ChEMBL
LigandPNGBDBM50326157(8-[2-(4-Morpholinophenyl)thiazol-4-yl]dibenzo[b,d]...)
Affinity DataIC50: 1.63E+3nMAssay Description:Inhibition of human recombinant TCPTP after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Glenmark Research Center

Curated by ChEMBL
LigandPNGBDBM50326155(8-{2-[4-(Pyrrolidin-1-yl)phenyl]thiazol-4-yl}diben...)
Affinity DataIC50: 1.66E+3nMAssay Description:Inhibition of human recombinant TCPTP after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Glenmark Research Center

Curated by ChEMBL
LigandPNGBDBM50296382((3S)-7-{4-[(3R)-1,2-Dithiolan-3-yl]butylcarboxamid...)
Affinity DataIC50: 1.82E+3nMAssay Description:Inhibition of human recombinant TCPTP after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Glenmark Research Center

Curated by ChEMBL
LigandPNGBDBM50326161(8-[2-(4-Iodophenyl)thiazol-4-yl]dibenzo[b,d]furan-...)
Affinity DataIC50: 1.88E+3nMAssay Description:Inhibition of human recombinant TCPTP after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase F(Human)
Glenmark Research Center

Curated by ChEMBL
LigandPNGBDBM50326163((E)-8-{2-[4-(2-Carboxyvinyl)phenyl]thiazol-4-yl}di...)
Affinity DataIC50: 1.98E+3nMAssay Description:Inhibition of human recombinant LAR after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Glenmark Research Center

Curated by ChEMBL
LigandPNGBDBM50326156(8-{2-[4-(Piperidin-1-yl)phenyl]thiazol-4-yl}dibenz...)
Affinity DataIC50: 2.07E+3nMAssay Description:Inhibition of human recombinant TCPTP after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase F(Human)
Glenmark Research Center

Curated by ChEMBL
LigandPNGBDBM50326164((E)-8-{2-[3-(2-Carboxyvinyl)phenyl]thiazol-4-yl}di...)
Affinity DataIC50: 2.07E+3nMAssay Description:Inhibition of human recombinant LAR after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase F(Human)
Glenmark Research Center

Curated by ChEMBL
LigandPNGBDBM50326156(8-{2-[4-(Piperidin-1-yl)phenyl]thiazol-4-yl}dibenz...)
Affinity DataIC50: 2.07E+3nMAssay Description:Inhibition of human recombinant LAR after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Glenmark Research Center

Curated by ChEMBL
LigandPNGBDBM50326159(8-[2-(4-Carboxyphenyl)thiazol-4-yl]dibenzo[b,d]fur...)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of human recombinant TCPTP after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase F(Human)
Glenmark Research Center

Curated by ChEMBL
LigandPNGBDBM50326162(8-[2-(3-Iodophenyl)thiazol-4-yl]dibenzo[b,d]furan-...)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of human recombinant LAR after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase F(Human)
Glenmark Research Center

Curated by ChEMBL
LigandPNGBDBM50326158(8-{2-[4-(2,6-Dimethylmorpholino)phenyl]thiazol-4-y...)
Affinity DataIC50: 2.14E+3nMAssay Description:Inhibition of human recombinant LAR after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase F(Human)
Glenmark Research Center

Curated by ChEMBL
LigandPNGBDBM50326161(8-[2-(4-Iodophenyl)thiazol-4-yl]dibenzo[b,d]furan-...)
Affinity DataIC50: 2.65E+3nMAssay Description:Inhibition of human recombinant LAR after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase F(Human)
Glenmark Research Center

Curated by ChEMBL
LigandPNGBDBM50326153(8-[2-(4-Aminophenyl)thiazol-4-yl]dibenzo[b,d]furan...)
Affinity DataIC50: 2.69E+3nMAssay Description:Inhibition of human recombinant LAR after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase F(Human)
Glenmark Research Center

Curated by ChEMBL
LigandPNGBDBM50326152(8-[2-(4-Nitrophenyl)thiazol-4-yl]dibenzo[b,d]furan...)
Affinity DataIC50: 2.87E+3nMAssay Description:Inhibition of human recombinant LAR after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase F(Human)
Glenmark Research Center

Curated by ChEMBL
LigandPNGBDBM50326157(8-[2-(4-Morpholinophenyl)thiazol-4-yl]dibenzo[b,d]...)
Affinity DataIC50: 2.94E+3nMAssay Description:Inhibition of human recombinant LAR after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase F(Human)
Glenmark Research Center

Curated by ChEMBL
LigandPNGBDBM50326155(8-{2-[4-(Pyrrolidin-1-yl)phenyl]thiazol-4-yl}diben...)
Affinity DataIC50: 2.99E+3nMAssay Description:Inhibition of human recombinant LAR after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Glenmark Research Center

Curated by ChEMBL
LigandPNGBDBM50326160(8-[2-(3,5-Dibromo-4-(1-carboxy-2-phenylethoxy)phen...)
Affinity DataIC50: 3.14E+3nMAssay Description:Inhibition of human recombinant TCPTP after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Glenmark Research Center

Curated by ChEMBL
LigandPNGBDBM50326166(2-(4-(benzyloxy)-3-(2-(2-(4-chlorophenyl)-4-methyl...)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of human recombinant PTP1B after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase F(Human)
Glenmark Research Center

Curated by ChEMBL
LigandPNGBDBM50326159(8-[2-(4-Carboxyphenyl)thiazol-4-yl]dibenzo[b,d]fur...)
Affinity DataIC50: 3.25E+3nMAssay Description:Inhibition of human recombinant LAR after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase F(Human)
Glenmark Research Center

Curated by ChEMBL
LigandPNGBDBM50326160(8-[2-(3,5-Dibromo-4-(1-carboxy-2-phenylethoxy)phen...)
Affinity DataIC50: 3.57E+3nMAssay Description:Inhibition of human recombinant LAR after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase F(Human)
Glenmark Research Center

Curated by ChEMBL
LigandPNGBDBM50326154(8-{2-[4-(Dimethylamino)phenyl]thiazol-4-yl}dibenzo...)
Affinity DataIC50: 3.75E+3nMAssay Description:Inhibition of human recombinant LAR after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Glenmark Research Center

Curated by ChEMBL
LigandPNGBDBM50326165(oxalylaminobenzoic acid | CHEMBL1241315)
Affinity DataKi:  18nMAssay Description:Inhibition of human recombinant PTP1B after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Glenmark Research Center

Curated by ChEMBL
LigandPNGBDBM50326165(oxalylaminobenzoic acid | CHEMBL1241315)
Affinity DataKi:  65nMAssay Description:Inhibition of human recombinant TCPTP after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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