Compile Data Set for Download or QSAR
Report error Found 28 Enz. Inhib. hit(s) with all data for entry = 50032020
TargetHydroxycarboxylic acid receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50323394(5-(2,3,5-trifluorophenyl)-1,4,5,6-tetrahydrocyclop...)
Affinity DataIC50: 20nMAssay Description:Displacement of [3H]nicotinic acid from human GPR10a receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50323394(5-(2,3,5-trifluorophenyl)-1,4,5,6-tetrahydrocyclop...)
Affinity DataIC50: 30nMAssay Description:Displacement of [3H]nicotinic acid from mouse GPR10a receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50277789(3-(1H-tetrazol-5-yl)-5-(2,3,5-trifluorophenyl)-1,4...)
Affinity DataIC50: 70nMAssay Description:Displacement of [3H]nicotinic acid from mouse GPR10a receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50277789(3-(1H-tetrazol-5-yl)-5-(2,3,5-trifluorophenyl)-1,4...)
Affinity DataIC50: 80nMAssay Description:Displacement of [3H]nicotinic acid from human GPR10a receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50323396(5-(thiophen-3-yl)-1,4,5,6-tetrahydrocyclopenta[c]p...)
Affinity DataIC50: 80nMAssay Description:Displacement of [3H]nicotinic acid from mouse GPR10a receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50323396(5-(thiophen-3-yl)-1,4,5,6-tetrahydrocyclopenta[c]p...)
Affinity DataIC50: 90nMAssay Description:Displacement of [3H]nicotinic acid from human GPR10a receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM23515(pyridine-3-carboxylic acid | CHEMBL573 | [5, 6-3H]...)
Affinity DataIC50: 140nMAssay Description:Displacement of [3H]nicotinic acid from mouse GPR10a receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetHydroxycarboxylic acid receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM23515(pyridine-3-carboxylic acid | CHEMBL573 | [5, 6-3H]...)
Affinity DataIC50: 140nMAssay Description:Displacement of [3H]nicotinic acid from human GPR10a receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetHydroxycarboxylic acid receptor 2(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50323393(5-phenyl-1,4,5,6-tetrahydrocyclopenta[c]pyrazole-3...)
Affinity DataIC50: 150nMAssay Description:Displacement of [3H]nicotinic acid from mouse GPR10a receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50323393(5-phenyl-1,4,5,6-tetrahydrocyclopenta[c]pyrazole-3...)
Affinity DataIC50: 200nMAssay Description:Displacement of [3H]nicotinic acid from human GPR10a receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50323395(5-(thiophen-2-yl)-1,4,5,6-tetrahydrocyclopenta[c]p...)
Affinity DataIC50: 240nMAssay Description:Displacement of [3H]nicotinic acid from human GPR10a receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50323395(5-(thiophen-2-yl)-1,4,5,6-tetrahydrocyclopenta[c]p...)
Affinity DataIC50: 250nMAssay Description:Displacement of [3H]nicotinic acid from mouse GPR10a receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50323390(5-propyl-1,4,5,6-tetrahydrocyclopenta[c]pyrazole-3...)
Affinity DataIC50: 250nMAssay Description:Displacement of [3H]nicotinic acid from mouse GPR10a receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50323390(5-propyl-1,4,5,6-tetrahydrocyclopenta[c]pyrazole-3...)
Affinity DataIC50: 380nMAssay Description:Displacement of [3H]nicotinic acid from human GPR10a receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50323398(5-(1-methyl-1H-pyrazol-5-yl)-1,4,5,6-tetrahydrocyc...)
Affinity DataIC50: 390nMAssay Description:Displacement of [3H]nicotinic acid from human GPR10a receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50323398(5-(1-methyl-1H-pyrazol-5-yl)-1,4,5,6-tetrahydrocyc...)
Affinity DataIC50: 450nMAssay Description:Displacement of [3H]nicotinic acid from mouse GPR10a receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50323391(5-isopropyl-1,4,5,6-tetrahydrocyclopenta[c]pyrazol...)
Affinity DataIC50: 990nMAssay Description:Displacement of [3H]nicotinic acid from mouse GPR10a receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50323392(5-sec-butyl-1,4,5,6-tetrahydrocyclopenta[c]pyrazol...)
Affinity DataIC50: 1.10E+3nMAssay Description:Displacement of [3H]nicotinic acid from mouse GPR10a receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50273099(MK-0354 | 3-(1H-tetrazol-5-yl)-1,4,5,6-tetrahydroc...)
Affinity DataIC50: 1.20E+3nMAssay Description:Displacement of [3H]nicotinic acid from mouse GPR10a receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50323392(5-sec-butyl-1,4,5,6-tetrahydrocyclopenta[c]pyrazol...)
Affinity DataIC50: 1.30E+3nMAssay Description:Displacement of [3H]nicotinic acid from human GPR10a receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50273099(MK-0354 | 3-(1H-tetrazol-5-yl)-1,4,5,6-tetrahydroc...)
Affinity DataIC50: 1.50E+3nMAssay Description:Displacement of [3H]nicotinic acid from human GPR10a receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50323397(5-(1-methyl-1H-pyrazol-4-yl)-1,4,5,6-tetrahydrocyc...)
Affinity DataIC50: 1.60E+3nMAssay Description:Displacement of [3H]nicotinic acid from mouse GPR10a receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50323391(5-isopropyl-1,4,5,6-tetrahydrocyclopenta[c]pyrazol...)
Affinity DataIC50: 1.70E+3nMAssay Description:Displacement of [3H]nicotinic acid from human GPR10a receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50323399(5-(1H-pyrazol-1-yl)-1,4,5,6-tetrahydrocyclopenta[c...)
Affinity DataIC50: 1.90E+3nMAssay Description:Displacement of [3H]nicotinic acid from human GPR10a receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50323397(5-(1-methyl-1H-pyrazol-4-yl)-1,4,5,6-tetrahydrocyc...)
Affinity DataIC50: 2.10E+3nMAssay Description:Displacement of [3H]nicotinic acid from human GPR10a receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50323399(5-(1H-pyrazol-1-yl)-1,4,5,6-tetrahydrocyclopenta[c...)
Affinity DataIC50: 3.40E+3nMAssay Description:Displacement of [3H]nicotinic acid from mouse GPR10a receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50323400(5-(1H-1,2,3-triazol-1-yl)-1,4,5,6-tetrahydrocyclop...)
Affinity DataIC50: 4.00E+3nMAssay Description:Displacement of [3H]nicotinic acid from human GPR10a receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50323400(5-(1H-1,2,3-triazol-1-yl)-1,4,5,6-tetrahydrocyclop...)
Affinity DataIC50: 5.20E+3nMAssay Description:Displacement of [3H]nicotinic acid from mouse GPR10a receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed