Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 50032919
TargetBeta-lactamase(Pseudomonas aeruginosa)
Toho University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50336509(Mercapto-acetic acid | Mercaptoacetic acid | SULFA...)
Affinity DataKi:  180nMAssay Description:Inhibition of Pseudomonas aeruginosa beta-lactamase IMP-1 assessed as hydrolysis of nitrocefin by UV spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetBeta-lactamase(Pseudomonas aeruginosa)
Toho University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50336510(7,8-dihydroxy-1-methoxy-3-methyl-10-oxo-1,10-dihyd...)
Affinity DataKi:  180nMAssay Description:Inhibition of Pseudomonas aeruginosa beta-lactamase IMP-1 assessed as hydrolysis of nitrocefin by UV spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetBeta-lactamase(Pseudomonas aeruginosa)
Toho University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50121953(3-sulfanylpropanoic acid | 3-mercaptopropanoic aci...)
Affinity DataKi:  180nMAssay Description:Inhibition of Pseudomonas aeruginosa beta-lactamase IMP-1 assessed as hydrolysis of nitrocefin by UV spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetBeta-lactamase(Pseudomonas aeruginosa)
Toho University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50336511((4R,5S,6S)-3-(benzo[b]thiophen-2-ylthio)-6-((R)-1-...)
Affinity DataKi:  180nMAssay Description:Inhibition of Pseudomonas aeruginosa beta-lactamase IMP-1 assessed as hydrolysis of nitrocefin by UV spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetBeta-lactamase(Pseudomonas aeruginosa)
Toho University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50336508(sodium 2,3-diethylmaleate | CHEMBL1673299)
Affinity DataKi:  410nMAssay Description:Inhibition of Pseudomonas aeruginosa beta-lactamase IMP-1 assessed as hydrolysis of nitrocefin by UV spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetMetallo-beta-lactamase VIM-2(Pseudomonas aeruginosa (g-Proteobacteria))
Toho University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50336508(sodium 2,3-diethylmaleate | CHEMBL1673299)
Affinity DataKi:  1.20E+5nMAssay Description:Inhibition of Pseudomonas aeruginosa beta-lactamase VIM-2 assessed as hydrolysis of nitrocefin by UV spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed