Compile Data Set for Download or QSAR
Report error Found 41 Enz. Inhib. hit(s) with all data for entry = 50039235
TargetC-C chemokine receptor type 5(Human)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50322288(4-(4-{[(3S)-1-Butyl-3-(cyclohexylmethyl)-2,5-dioxo...)
Affinity DataIC50: 13nMAssay Description:Antagonist activity at human CCR5 receptor expressed in CHO cells assessed as inhibition of MIP-1-alpha-stmulated calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50322271(rac-1-Butyl-3-(cyclohexylmethyl)-9-[(6-phenoxypyri...)
Affinity DataIC50: 21nMAssay Description:Antagonist activity at human CCR5 receptor expressed in CHO cells assessed as inhibition of MIP-1-alpha-stmulated calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50190516(1-butyl-3-cyclohexylmethyl-9-(4-phenoxy-benzyl)-1,...)
Affinity DataIC50: 28nMAssay Description:Antagonist activity at human CCR5 receptor expressed in CHO cells assessed as inhibition of MIP-1-alpha-stmulated calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50322287(4-(4-{[(3S)-1-Butyl-3-(cyclohexylmethyl)-2,5-dioxo...)
Affinity DataIC50: 28nMAssay Description:Antagonist activity at human CCR5 receptor expressed in CHO cells assessed as inhibition of MIP-1-alpha-stmulated calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50322285(4-(4-{[(3S)-1-Butyl-3-(cyclohexylmethyl)-2,5-dioxo...)
Affinity DataIC50: 33nMAssay Description:Antagonist activity at human CCR5 receptor expressed in CHO cells assessed as inhibition of MIP-1-alpha-stmulated calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50322273(rac-1-Butyl-3-(cyclohexylmethyl)-9-[(3,5-dimethyl-...)
Affinity DataIC50: 35nMAssay Description:Antagonist activity at human CCR5 receptor expressed in CHO cells assessed as inhibition of MIP-1-alpha-stmulated calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50322286(N-[4-(4-{[(3S)-1-Butyl-3-(cyclohexylmethyl)-2,5-di...)
Affinity DataIC50: 40nMAssay Description:Antagonist activity at human CCR5 receptor expressed in CHO cells assessed as inhibition of MIP-1-alpha-stmulated calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50322284((3S)-1-Butyl-3-(cyclohexylmethyl)-9-[4-(4-hydroxyp...)
Affinity DataIC50: 42nMAssay Description:Antagonist activity at human CCR5 receptor expressed in CHO cells assessed as inhibition of MIP-1-alpha-stmulated calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50322262(rac-1-Butyl-9-(4-phenoxybenzyl)-3-propyl-1,4,9-tri...)
Affinity DataIC50: 50nMAssay Description:Antagonist activity at human CCR5 receptor expressed in CHO cells assessed as inhibition of MIP-1-alpha-stmulated calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50322263(rac-1-Butyl-3-(cyclopentylmethyl)-9-(4-phenoxybenz...)
Affinity DataIC50: 52nMAssay Description:Antagonist activity at human CCR5 receptor expressed in CHO cells assessed as inhibition of MIP-1-alpha-stmulated calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50322259(rac-1-(2-Butynyl)-3-isobutyl-9-(4-phenoxybenzyl)-1...)
Affinity DataIC50: 54nMAssay Description:Antagonist activity at human CCR5 receptor expressed in CHO cells assessed as inhibition of MIP-1-alpha-stmulated calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50322280(4-{[(3S)-1-Butyl-3-(cyclohexylmethyl)-2,5-dioxo-1,...)
Affinity DataIC50: 57nMAssay Description:Antagonist activity at human CCR5 receptor expressed in CHO cells assessed as inhibition of MIP-1-alpha-stmulated calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50322258(rac-1-[(2E)-2-Butenyl]-3-isobutyl-9-(4-phenoxybenz...)
Affinity DataIC50: 69nMAssay Description:Antagonist activity at human CCR5 receptor expressed in CHO cells assessed as inhibition of MIP-1-alpha-stmulated calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50322272((3S)-1-Butyl-3-(cyclohexylmethyl)-9-[(6-phenylpyri...)
Affinity DataIC50: 71nMAssay Description:Antagonist activity at human CCR5 receptor expressed in CHO cells assessed as inhibition of MIP-1-alpha-stmulated calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50322261((3S)-1-Butyl-3-neopentyl-9-(4-phenoxybenzyl)-1,4,9...)
Affinity DataIC50: 79nMAssay Description:Antagonist activity at human CCR5 receptor expressed in CHO cells assessed as inhibition of MIP-1-alpha-stmulated calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50322282((3S)-1-Butyl-3-(cyclohexylmethyl)-9-[4-(4-methylph...)
Affinity DataIC50: 79nMAssay Description:Antagonist activity at human CCR5 receptor expressed in CHO cells assessed as inhibition of MIP-1-alpha-stmulated calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50322279((3S)-9-(4-Benzoylbenzyl)-1-butyl-3-(cyclohexylmeth...)
Affinity DataIC50: 81nMAssay Description:Antagonist activity at human CCR5 receptor expressed in CHO cells assessed as inhibition of MIP-1-alpha-stmulated calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50198940((3S)-1-Butyl-3-isobutyl-9-(4-phenoxybenzyl)-1,4,9-...)
Affinity DataIC50: 84nMAssay Description:Antagonist activity at human CCR5 receptor expressed in CHO cells assessed as inhibition of MIP-1-alpha-stmulated calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50322278((3S)-1-Butyl-3-(cyclohexylmethyl)-9-[4-(phenylsulf...)
Affinity DataIC50: 86nMAssay Description:Antagonist activity at human CCR5 receptor expressed in CHO cells assessed as inhibition of MIP-1-alpha-stmulated calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50322281((3S)-1-Butyl-3-(cyclohexylmethyl)-9-[4-(4-fluoroph...)
Affinity DataIC50: 92nMAssay Description:Antagonist activity at human CCR5 receptor expressed in CHO cells assessed as inhibition of MIP-1-alpha-stmulated calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50190520(rac-1-Butyl-3-isobutyl-9-(4-phenoxybenzyl)-1,4,9-t...)
Affinity DataIC50: 94nMAssay Description:Antagonist activity at human CCR5 receptor expressed in CHO cells assessed as inhibition of MIP-1-alpha-stmulated calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50190525(rac-1-Butyl-3-(cyclohexylmethyl)-9-(4-methoxybenzy...)
Affinity DataIC50: 120nMAssay Description:Antagonist activity at human CCR5 receptor expressed in CHO cells assessed as inhibition of MIP-1-alpha-stmulated calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50198937((3R)-1-Butyl-3-isobutyl-9-(4-phenoxybenzyl)-1,4,9-...)
Affinity DataIC50: 130nMAssay Description:Antagonist activity at human CCR5 receptor expressed in CHO cells assessed as inhibition of MIP-1-alpha-stmulated calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50322283((3S)-1-Butyl-3-(cyclohexylmethyl)-9-[4-(4-methoxyp...)
Affinity DataIC50: 130nMAssay Description:Antagonist activity at human CCR5 receptor expressed in CHO cells assessed as inhibition of MIP-1-alpha-stmulated calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50322274(rac-1-Butyl-3-(cyclohexylmethyl)-9-[(2-phenyl-1H-i...)
Affinity DataIC50: 160nMAssay Description:Antagonist activity at human CCR5 receptor expressed in CHO cells assessed as inhibition of MIP-1-alpha-stmulated calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50322277((3S)-1-Butyl-3-(cyclohexylmethyl)-9-[4-(phenylsulf...)
Affinity DataIC50: 170nMAssay Description:Antagonist activity at human CCR5 receptor expressed in CHO cells assessed as inhibition of MIP-1-alpha-stmulated calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50190518(1-butyl-3-(2-methylpropyl)-9-(6-phenylhexyl)-1,4,9...)
Affinity DataIC50: 270nMAssay Description:Antagonist activity at human CCR5 receptor expressed in CHO cells assessed as inhibition of MIP-1-alpha-stmulated calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50322260(rac-1-Benzyl-3-isobutyl-9-(4-phenoxybenzyl)-1,4,9-...)
Affinity DataIC50: 300nMAssay Description:Antagonist activity at human CCR5 receptor expressed in CHO cells assessed as inhibition of MIP-1-alpha-stmulated calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50322264(rac-1-Butyl-3-(methoxymethyl)-9-(4-phenoxybenzyl)-...)
Affinity DataIC50: 320nMAssay Description:Antagonist activity at human CCR5 receptor expressed in CHO cells assessed as inhibition of MIP-1-alpha-stmulated calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50322256(rac-1,3-Diisobutyl-9-(4-phenoxybenzyl)-1,4,9-triaz...)
Affinity DataIC50: 330nMAssay Description:Antagonist activity at human CCR5 receptor expressed in CHO cells assessed as inhibition of MIP-1-alpha-stmulated calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50322275((3S)-1-Butyl-3-(cyclohexylmethyl)-9-[(5-methyl-2-p...)
Affinity DataIC50: 450nMAssay Description:Antagonist activity at human CCR5 receptor expressed in CHO cells assessed as inhibition of MIP-1-alpha-stmulated calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50190524(rac-3-Isobutyl-9-(4-phenoxybenzyl)-1-propyl-1,4,9-...)
Affinity DataIC50: 500nMAssay Description:Antagonist activity at human CCR5 receptor expressed in CHO cells assessed as inhibition of MIP-1-alpha-stmulated calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50322276(rac-1-Butyl-3-(cyclohexylmethyl)-9-[(2-phenyl-1,3-...)
Affinity DataIC50: 570nMAssay Description:Antagonist activity at human CCR5 receptor expressed in CHO cells assessed as inhibition of MIP-1-alpha-stmulated calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50322266(rac-Benzyl [1-butyl-2,5-dioxo-9-(4-phenoxybenzyl)-...)
Affinity DataIC50: 590nMAssay Description:Antagonist activity at human CCR5 receptor expressed in CHO cells assessed as inhibition of MIP-1-alpha-stmulated calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50190522((RS)-9-benzyl-1-butyl-3-isobutyl-1,4,9-triazaspiro...)
Affinity DataIC50: 900nMAssay Description:Antagonist activity at human CCR5 receptor expressed in CHO cells assessed as inhibition of MIP-1-alpha-stmulated calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50322267(rac-1-Butyl-3-(3-cyclohexylpropyl)-9-(4-phenoxyben...)
Affinity DataIC50: 3.00E+3nMAssay Description:Antagonist activity at human CCR5 receptor expressed in CHO cells assessed as inhibition of MIP-1-alpha-stmulated calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50322265(rac-[1-Butyl-2,5-dioxo-9-(4-phenoxybenzyl)-1,4,9-t...)
Affinity DataIC50: 3.00E+3nMAssay Description:Antagonist activity at human CCR5 receptor expressed in CHO cells assessed as inhibition of MIP-1-alpha-stmulated calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50322257(1-(3-hydroxy-butyl)-3-isobutyl-9-(4-phenoxy-benzyl...)
Affinity DataIC50: 3.00E+3nMAssay Description:Antagonist activity at human CCR5 receptor expressed in CHO cells assessed as inhibition of MIP-1-alpha-stmulated calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50322268((3S)-1-Butyl-3-(cyclohexylmethyl)-9-[2-(4-phenoxyp...)
Affinity DataIC50: 3.00E+3nMAssay Description:Antagonist activity at human CCR5 receptor expressed in CHO cells assessed as inhibition of MIP-1-alpha-stmulated calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50322269(rac-Ethyl 4-[1-butyl-3-(cyclohexylmethyl)-2,5-diox...)
Affinity DataIC50: 3.00E+3nMAssay Description:Antagonist activity at human CCR5 receptor expressed in CHO cells assessed as inhibition of MIP-1-alpha-stmulated calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50322270(rac-Benzyl 1-butyl-3-(cyclohexylmethyl)-2,5-dioxo-...)
Affinity DataIC50: 3.00E+3nMAssay Description:Antagonist activity at human CCR5 receptor expressed in CHO cells assessed as inhibition of MIP-1-alpha-stmulated calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed