Compile Data Set for Download or QSAR
Report error Found 142 Enz. Inhib. hit(s) with all data for entry = 50039191
TargetProgesterone receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50321196(rac-3-(4-Nitrophenylamino)-1-(4-bromophenyl)-3-cyc...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human progesterone receptor B expressed in african green monkey CV1 cells co-transfected with MMTV-Luc after 24 hrs by luciferase...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProgesterone receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50321197(rac-3-(4-Nitrophenylamino)-1-(4-chlorophenyl)-3-cy...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human progesterone receptor B expressed in african green monkey CV1 cells co-transfected with MMTV-Luc after 24 hrs by luciferase...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProgesterone receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50321199(rac-3-(4-Nitrophenylamino)-3-cyclohexyl-1-(3-fluor...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human progesterone receptor B expressed in african green monkey CV1 cells co-transfected with MMTV-Luc after 24 hrs by luciferase...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProgesterone receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM8903(CHEMBL103 | (1S,2R,10S,11S,14S,15S)-14-acetyl-2,15...)
Affinity DataEC50:  15.2nMAssay Description:Agonist activity at human progesterone receptor B expressed in african green monkey CV1 cells co-transfected with MMTV-Luc after 24 hrs by luciferase...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProgesterone receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50321176(rac-3-(4-Nitrophenylamino)-3-(3-fluorophenyl)-1-p-...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human progesterone receptor B expressed in african green monkey CV1 cells co-transfected with MMTV-Luc after 24 hrs by luciferase...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMineralocorticoid receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50321176(rac-3-(4-Nitrophenylamino)-3-(3-fluorophenyl)-1-p-...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human mineralocorticoid receptor expressed in african green monkey CV1 cells co-transfected with MMTV-Luc after 24 hrs by lucifer...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEstrogen receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50321176(rac-3-(4-Nitrophenylamino)-3-(3-fluorophenyl)-1-p-...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human ERalpha expressed in african green monkey CV1 cells co-transfected with ERE-MMTV-Luc after 24 hrs by luciferase reporter ge...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEstrogen receptor beta(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50321176(rac-3-(4-Nitrophenylamino)-3-(3-fluorophenyl)-1-p-...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human ERbeta expressed in african green monkey CV1 cells co-transfected with ERE-MMTV-Luc after 24 hrs by luciferase reporter gen...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAndrogen receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50321176(rac-3-(4-Nitrophenylamino)-3-(3-fluorophenyl)-1-p-...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human androgen receptor expressed in african green monkey CV1 cells co-transfected with MMTV-Luc after 24 hrs by luciferase repor...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlucocorticoid receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50321176(rac-3-(4-Nitrophenylamino)-3-(3-fluorophenyl)-1-p-...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human glucocorticoid receptor expressed in african green monkey CV1 cells co-transfected with MMTV-Luc after 24 hrs by luciferase...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProgesterone receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50321177(rac-3-(4-Nitrophenylamino)-1-(3-chlorophenyl)-3-(3...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human progesterone receptor B expressed in african green monkey CV1 cells co-transfected with MMTV-Luc after 24 hrs by luciferase...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProgesterone receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50321178(rac-3-(4-Nitrophenylamino)-3-(3-fluorophenyl)-1-(4...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human progesterone receptor B expressed in african green monkey CV1 cells co-transfected with MMTV-Luc after 24 hrs by luciferase...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProgesterone receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50321179(rac-3-(4-Nitrophenylamino)-3-(4-(trifluoromethyl)p...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human progesterone receptor B expressed in african green monkey CV1 cells co-transfected with MMTV-Luc after 24 hrs by luciferase...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProgesterone receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50321180(rac-3-(4-Nitrophenylamino)-3-(4-(trifluoromethyl)p...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human progesterone receptor B expressed in african green monkey CV1 cells co-transfected with MMTV-Luc after 24 hrs by luciferase...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProgesterone receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50321181(rac-3-(4-Nitrophenylamino)-1-(4-bromophenyl)-3-(4-...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human progesterone receptor B expressed in african green monkey CV1 cells co-transfected with MMTV-Luc after 24 hrs by luciferase...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProgesterone receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50321182(rac-3-(4-Nitrophenylamino)-3-cyclohexyl-1-(4-metho...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human progesterone receptor B expressed in african green monkey CV1 cells co-transfected with MMTV-Luc after 24 hrs by luciferase...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMineralocorticoid receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM18627(Mifeprex | (10S,11S,14S,15S,17R)-17-[4-(dimethylam...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human mineralocorticoid receptor expressed in african green monkey CV1 cells co-transfected with MMTV-Luc after 24 hrs by lucifer...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAndrogen receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM18627(Mifeprex | (10S,11S,14S,15S,17R)-17-[4-(dimethylam...)
Affinity DataEC50:  10nMAssay Description:Agonist activity at human androgen receptor expressed in african green monkey CV1 cells co-transfected with MMTV-Luc after 24 hrs by luciferase repor...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlucocorticoid receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM18627(Mifeprex | (10S,11S,14S,15S,17R)-17-[4-(dimethylam...)
Affinity DataEC50:  872nMAssay Description:Agonist activity at human glucocorticoid receptor expressed in african green monkey CV1 cells co-transfected with MMTV-Luc after 24 hrs by luciferase...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProgesterone receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM18627(Mifeprex | (10S,11S,14S,15S,17R)-17-[4-(dimethylam...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human progesterone receptor B expressed in african green monkey CV1 cells co-transfected with MMTV-Luc after 24 hrs by luciferase...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProgesterone receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM18627(Mifeprex | (10S,11S,14S,15S,17R)-17-[4-(dimethylam...)
Affinity DataIC50: 0.600nMAssay Description:Antagonist activity at human progesterone receptor B expressed in african green monkey CV1 cells co-transfected with MMTV-Luc assessed as effect on p...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlucocorticoid receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM18627(Mifeprex | (10S,11S,14S,15S,17R)-17-[4-(dimethylam...)
Affinity DataIC50: 0.950nMAssay Description:Antagonist activity at human glucocorticoid receptor expressed in african green monkey CV1 cells co-transfected with MMTV-Luc by luciferase reporter ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAndrogen receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM18627(Mifeprex | (10S,11S,14S,15S,17R)-17-[4-(dimethylam...)
Affinity DataIC50: 1nMAssay Description:Antagonist activity at human androgen receptor expressed in african green monkey CV1 cells co-transfected with MMTV-Luc by luciferase reporter gene a...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAndrogen receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50321219(1-(4-chlorophenyl)-3-(furan-2-yl)-3-(4-nitrophenyl...)
Affinity DataIC50: 2.90nMAssay Description:Binding affinity to androgen receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProgesterone receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50321182(rac-3-(4-Nitrophenylamino)-3-cyclohexyl-1-(4-metho...)
Affinity DataIC50: 139nMAssay Description:Antagonist activity at human progesterone receptor B expressed in african green monkey CV1 cells co-transfected with MMTV-Luc assessed as effect on p...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAndrogen receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50321176(rac-3-(4-Nitrophenylamino)-3-(3-fluorophenyl)-1-p-...)
Affinity DataIC50: 140nMAssay Description:Antagonist activity at human androgen receptor expressed in african green monkey CV1 cells co-transfected with MMTV-Luc by luciferase reporter gene a...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProgesterone receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50321219(1-(4-chlorophenyl)-3-(furan-2-yl)-3-(4-nitrophenyl...)
Affinity DataIC50: 180nMAssay Description:Binding affinity to progesterone receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProgesterone receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50321199(rac-3-(4-Nitrophenylamino)-3-cyclohexyl-1-(3-fluor...)
Affinity DataIC50: 193nMAssay Description:Antagonist activity at human progesterone receptor B expressed in african green monkey CV1 cells co-transfected with MMTV-Luc assessed as effect on p...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProgesterone receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50321197(rac-3-(4-Nitrophenylamino)-1-(4-chlorophenyl)-3-cy...)
Affinity DataIC50: 216nMAssay Description:Antagonist activity at human progesterone receptor B expressed in african green monkey CV1 cells co-transfected with MMTV-Luc assessed as effect on p...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProgesterone receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50321178(rac-3-(4-Nitrophenylamino)-3-(3-fluorophenyl)-1-(4...)
Affinity DataIC50: 805nMAssay Description:Antagonist activity at human progesterone receptor B expressed in african green monkey CV1 cells co-transfected with MMTV-Luc assessed as effect on p...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProgesterone receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50321181(rac-3-(4-Nitrophenylamino)-1-(4-bromophenyl)-3-(4-...)
Affinity DataIC50: 1.21E+3nMAssay Description:Antagonist activity at human progesterone receptor B expressed in african green monkey CV1 cells co-transfected with MMTV-Luc assessed as effect on p...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProgesterone receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50321196(rac-3-(4-Nitrophenylamino)-1-(4-bromophenyl)-3-cyc...)
Affinity DataIC50: 1.56E+3nMAssay Description:Antagonist activity at human progesterone receptor B expressed in african green monkey CV1 cells co-transfected with MMTV-Luc assessed as effect on p...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProgesterone receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50321179(rac-3-(4-Nitrophenylamino)-3-(4-(trifluoromethyl)p...)
Affinity DataIC50: 1.83E+3nMAssay Description:Antagonist activity at human progesterone receptor B expressed in african green monkey CV1 cells co-transfected with MMTV-Luc assessed as effect on p...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProgesterone receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50321180(rac-3-(4-Nitrophenylamino)-3-(4-(trifluoromethyl)p...)
Affinity DataIC50: 2.70E+3nMAssay Description:Antagonist activity at human progesterone receptor B expressed in african green monkey CV1 cells co-transfected with MMTV-Luc assessed as effect on p...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProgesterone receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50321177(rac-3-(4-Nitrophenylamino)-1-(3-chlorophenyl)-3-(3...)
Affinity DataIC50: 3.54E+3nMAssay Description:Antagonist activity at human progesterone receptor B expressed in african green monkey CV1 cells co-transfected with MMTV-Luc assessed as effect on p...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProgesterone receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50321176(rac-3-(4-Nitrophenylamino)-3-(3-fluorophenyl)-1-p-...)
Affinity DataIC50: 6.06E+3nMAssay Description:Antagonist activity at human progesterone receptor B expressed in african green monkey CV1 cells co-transfected with MMTV-Luc assessed as effect on p...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProgesterone receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM8903(CHEMBL103 | (1S,2R,10S,11S,14S,15S)-14-acetyl-2,15...)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human progesterone receptor B expressed in african green monkey CV1 cells co-transfected with MMTV-Luc assessed as effect on p...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEstrogen receptor beta(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50321176(rac-3-(4-Nitrophenylamino)-3-(3-fluorophenyl)-1-p-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human ERbeta expressed in african green monkey CV1 cells co-transfected with ERE-MMTV-Luc by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMineralocorticoid receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50321176(rac-3-(4-Nitrophenylamino)-3-(3-fluorophenyl)-1-p-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human mineralocorticoid receptor expressed in african green monkey CV1 cells co-transfected with MMTV-Luc by luciferase report...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlucocorticoid receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50321176(rac-3-(4-Nitrophenylamino)-3-(3-fluorophenyl)-1-p-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human glucocorticoid receptor expressed in african green monkey CV1 cells co-transfected with MMTV-Luc by luciferase reporter ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEstrogen receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50321176(rac-3-(4-Nitrophenylamino)-3-(3-fluorophenyl)-1-p-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human ERalpha expressed in african green monkey CV1 cells co-transfected with ERE-MMTV-Luc by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMineralocorticoid receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM18627(Mifeprex | (10S,11S,14S,15S,17R)-17-[4-(dimethylam...)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human mineralocorticoid receptor expressed in african green monkey CV1 cells co-transfected with MMTV-Luc by luciferase report...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlucocorticoid receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM18627(Mifeprex | (10S,11S,14S,15S,17R)-17-[4-(dimethylam...)
Affinity DataKi:  0.840nMAssay Description:Displacement of [3H]dexamethasone from human glucocorticoid receptor after 16 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAndrogen receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50321202(rac-3-(4-Nitrophenylamino)-1-(4-cyanophenyl)-3-(th...)
Affinity DataKi:  2.30nMAssay Description:Displacement of [3H]DHT from human androgen receptor after 16 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAndrogen receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM18161(DHT | Dihydrotestosterone | [3H]DHT | (5alpha,17be...)
Affinity DataKi:  4.70nMAssay Description:Displacement of [3H]DHT from human androgen receptor after 16 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetProgesterone receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM8903(CHEMBL103 | (1S,2R,10S,11S,14S,15S)-14-acetyl-2,15...)
Affinity DataKi:  5.10nMAssay Description:Displacement of [3H]progesterone from human progesterone receptor B after 16 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProgesterone receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50321197(rac-3-(4-Nitrophenylamino)-1-(4-chlorophenyl)-3-cy...)
Affinity DataKi:  6.70nMAssay Description:Displacement of [3H]progesterone from human progesterone receptor B after 16 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAndrogen receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM18627(Mifeprex | (10S,11S,14S,15S,17R)-17-[4-(dimethylam...)
Affinity DataKi:  8.40nMAssay Description:Displacement of [3H]DHT from human androgen receptor after 16 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProgesterone receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50321198(rac-3-(4-Nitrophenylamino)-3-cyclohexyl-1-(4-fluor...)
Affinity DataKi:  8.5nMAssay Description:Displacement of [3H]progesterone from human progesterone receptor B after 16 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProgesterone receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50321199(rac-3-(4-Nitrophenylamino)-3-cyclohexyl-1-(3-fluor...)
Affinity DataKi:  8.5nMAssay Description:Displacement of [3H]progesterone from human progesterone receptor B after 16 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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