Compile Data Set for Download or QSAR
Report error Found 44 Enz. Inhib. hit(s) with all data for entry = 50031896
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50321153((1-(3-bromobenzoyl)piperidin-4-yl)(4-fluorophenyl)...)
Affinity DataIC50: 2.79E+3nMAssay Description:Inhibition of human 11beta-HSD1 by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50321171((1-(3-(dimethylamino)benzoyl)piperidin-4-yl)(4-flu...)
Affinity DataIC50: 3.15E+3nMAssay Description:Inhibition of human 11beta-HSD1 by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50321164((1-(4-bromobenzoyl)piperidin-4-yl)(4-fluorophenyl)...)
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of human 11beta-HSD1 by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50321161((4-(4-fluorobenzoyl)piperidin-1-yl)(p-tolyl)methan...)
Affinity DataIC50: 3.41E+3nMAssay Description:Inhibition of human 11beta-HSD1 by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50321169((1-(3,4-dichlorobenzoyl)piperidin-4-yl)(4-fluoroph...)
Affinity DataIC50: 3.52E+3nMAssay Description:Inhibition of human 11beta-HSD1 by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50321151((1-benzoylpiperidin-4-yl)(4-fluorophenyl)methanone...)
Affinity DataIC50: 3.61E+3nMAssay Description:Inhibition of human 11beta-HSD1 by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50321137((4-(4-fluorobenzoyl)piperidin-1-yl)(3-(trifluorome...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of human 11beta-HSD1 by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50321175((1-(2-chlorobenzoyl)piperidin-4-yl)(4-fluorophenyl...)
Affinity DataIC50: 4.06E+3nMAssay Description:Inhibition of human 11beta-HSD1 by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50321158((4-(4-fluorobenzoyl)piperidin-1-yl)(3-methoxypheny...)
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of human 11beta-HSD1 by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50321173((1-(4-chloro-3-(trifluoromethyl)benzoyl)piperidin-...)
Affinity DataIC50: 4.65E+3nMAssay Description:Inhibition of human 11beta-HSD1 by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50321167((4-(4-fluorobenzoyl)piperidin-1-yl)(4-(trifluorome...)
Affinity DataIC50: 5.45E+3nMAssay Description:Inhibition of human 11beta-HSD1 by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50321142((4-(4-fluorobenzoyl)piperidin-1-yl)(m-tolyl)methan...)
Affinity DataIC50: 5.93E+3nMAssay Description:Inhibition of human 11beta-HSD1 by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50321163((1-(4-chlorobenzoyl)piperidin-4-yl)(4-fluorophenyl...)
Affinity DataIC50: 6.02E+3nMAssay Description:Inhibition of human 11beta-HSD1 by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50321138(biphenyl-4-yl(4-(4-fluorobenzoyl)piperidin-1-yl)me...)
Affinity DataIC50: 6.12E+3nMAssay Description:Inhibition of human 11beta-HSD1 by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50321139(1-(4-(4-(4-fluorobenzoyl)piperidine-1-carbonyl)phe...)
Affinity DataIC50: 6.88E+3nMAssay Description:Inhibition of human 11beta-HSD1 by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50321166((4-(4-fluorobenzoyl)piperidin-1-yl)(o-tolyl)methan...)
Affinity DataIC50: 6.89E+3nMAssay Description:Inhibition of human 11beta-HSD1 by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50321154((1-(3-chlorobenzoyl)piperidin-4-yl)(4-fluorophenyl...)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of human 11beta-HSD1 by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50321140((4-(4-fluorobenzoyl)piperidin-1-yl)(4-(trifluorome...)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of human 11beta-HSD1 by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50321134((4-(4-fluorobenzoyl)piperidin-1-yl)(2-fluorophenyl...)
Affinity DataIC50: 7.44E+3nMAssay Description:Inhibition of human 11beta-HSD1 by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50321141((1-(3,4-difluorobenzoyl)piperidin-4-yl)(4-fluoroph...)
Affinity DataIC50: 7.50E+3nMAssay Description:Inhibition of human 11beta-HSD1 by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50321155((4-(4-fluorobenzoyl)piperidin-1-yl)(3-(trifluorome...)
Affinity DataIC50: 9.06E+3nMAssay Description:Inhibition of human 11beta-HSD1 by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50321150((4-(4-fluorobenzoyl)piperidin-1-yl)(4-nitrophenyl)...)
Affinity DataIC50: 9.12E+3nMAssay Description:Inhibition of human 11beta-HSD1 by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50321168((1-(2-chloro-4-fluorobenzoyl)piperidin-4-yl)(4-flu...)
Affinity DataIC50: 9.67E+3nMAssay Description:Inhibition of human 11beta-HSD1 by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50321160(2-(4-(4-fluorobenzoyl)piperidine-1-carbonyl)benzon...)
Affinity DataIC50: 1.06E+4nMAssay Description:Inhibition of human 11beta-HSD1 by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50321174((1-(2-aminobenzoyl)piperidin-4-yl)(4-fluorophenyl)...)
Affinity DataIC50: 1.28E+4nMAssay Description:Inhibition of human 11beta-HSD1 by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50321133((4-(4-fluorobenzoyl)piperidin-1-yl)(4-morpholinoph...)
Affinity DataIC50: 1.35E+4nMAssay Description:Inhibition of human 11beta-HSD1 by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50321149((4-(4-fluorobenzoyl)piperidin-1-yl)(4-methoxypheny...)
Affinity DataIC50: 1.58E+4nMAssay Description:Inhibition of human 11beta-HSD1 by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50321152((4-(4-fluorobenzoyl)piperidin-1-yl)(2-(trifluorome...)
Affinity DataIC50: 1.83E+4nMAssay Description:Inhibition of human 11beta-HSD1 by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50321132(piperidine-1,4-diylbis((4-fluorophenyl)methanone) ...)
Affinity DataIC50: 2.18E+4nMAssay Description:Inhibition of human 11beta-HSD1 by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50321157((4-(4-fluorobenzoyl)piperidin-1-yl)(3-fluorophenyl...)
Affinity DataIC50: 2.19E+4nMAssay Description:Inhibition of human 11beta-HSD1 by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50321143((1-(2,3-dimethoxybenzoyl)piperidin-4-yl)(4-fluorop...)
Affinity DataIC50: 2.32E+4nMAssay Description:Inhibition of human 11beta-HSD1 by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50321146((4-(4-fluorobenzoyl)piperidin-1-yl)(2-methoxypheny...)
Affinity DataIC50: 2.36E+4nMAssay Description:Inhibition of human 11beta-HSD1 by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50321147((1-(2,4-dimethoxybenzoyl)piperidin-4-yl)(4-fluorop...)
Affinity DataIC50: 2.37E+4nMAssay Description:Inhibition of human 11beta-HSD1 by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50321170((4-(4-fluorobenzoyl)piperidin-1-yl)(3-nitrophenyl)...)
Affinity DataIC50: 2.56E+4nMAssay Description:Inhibition of human 11beta-HSD1 by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50321145((1-(3,5-difluorobenzoyl)piperidin-4-yl)(4-fluoroph...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human 11beta-HSD1 by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50321162(4-(4-(4-fluorobenzoyl)piperidine-1-carbonyl)benzon...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human 11beta-HSD1 by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50321144((1-(2,3-difluorobenzoyl)piperidin-4-yl)(4-fluoroph...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human 11beta-HSD1 by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50321165((4-(4-fluorobenzoyl)piperidin-1-yl)(4-(methylsulfo...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human 11beta-HSD1 by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50321156((4-(4-fluorobenzoyl)piperidin-1-yl)(3-(methylsulfo...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human 11beta-HSD1 by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50321136(3-(4-(4-fluorobenzoyl)piperidine-1-carbonyl)benzen...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human 11beta-HSD1 by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50321135(4-(4-(4-fluorobenzoyl)piperidine-1-carbonyl)benzen...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human 11beta-HSD1 by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50321172((1-(2,4-dichlorobenzoyl)piperidin-4-yl)(4-fluoroph...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human 11beta-HSD1 by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50321148(3-(4-(4-fluorobenzoyl)piperidine-1-carbonyl)benzon...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human 11beta-HSD1 by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50321159(N-(3-(4-(4-fluorobenzoyl)piperidine-1-carbonyl)phe...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human 11beta-HSD1 by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed