Compile Data Set for Download or QSAR
Report error Found 37 Enz. Inhib. hit(s) with all data for entry = 50031843
TargetCytochrome P450 2D6(Human)
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50320377((E)-(2-(4-(4-fluorostyryl)phenylsulfonyl)phenyl)me...)
Affinity DataIC50: 100nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50320375((E)-1-(2-(4-(4-fluorostyryl)phenylsulfonyl)phenyl)...)
Affinity DataKi:  0.0700nMAssay Description:Displacement of [3H]- ketanserin from human 5HT2A receptor expressed CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50320373((E)-3-(4-(2,4-difluorostyryl)phenylsulfonyl)benzam...)
Affinity DataKi:  0.200nMAssay Description:Displacement of [3H]- ketanserin from human 5HT2A receptor expressed CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50320376((S,E)-1-(2-(4-(4-fluorostyryl)phenylsulfonyl)pheny...)
Affinity DataKi:  0.220nMAssay Description:Displacement of [3H]- ketanserin from human 5HT2A receptor expressed CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50095027((2,3-Dimethoxy-phenyl)-{1-[2-(4-fluoro-phenyl)-eth...)
Affinity DataKi:  0.310nMAssay Description:Displacement of [3H]- ketanserin from human 5HT2A receptor expressed CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50169842(1-[2-(2,4-Difluoro-phenyl)-ethyl]-4-fluoro-4-(4-fl...)
Affinity DataKi:  0.390nMAssay Description:Displacement of [3H]- ketanserin from human 5HT2A receptor expressed CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50108699(1-(2,4-difluorophenethyl)-4-(4-fluorophenylsulfony...)
Affinity DataKi:  0.420nMAssay Description:Displacement of [3H]- ketanserin from human 5HT2A receptor expressed CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50320372((E)-2-(4-(2,4-difluorostyryl)phenylsulfonyl)benzam...)
Affinity DataKi:  0.650nMAssay Description:Displacement of [3H]- ketanserin from human 5HT2A receptor expressed CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50320374((E)-4-(4-(2,4-difluorostyryl)phenylsulfonyl)benzam...)
Affinity DataKi:  0.650nMAssay Description:Displacement of [3H]- ketanserin from human 5HT2A receptor expressed CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50320370((E)-2,4-difluoro-1-(4-(phenylsulfonyl)styryl)benze...)
Affinity DataKi:  1.32nMAssay Description:Displacement of [3H]- ketanserin from human 5HT2A receptor expressed CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50320371(2,4-difluoro-1-(4-(phenylsulfonyl)phenethyl)benzen...)
Affinity DataKi:  1.43nMAssay Description:Displacement of [3H]- ketanserin from human 5HT2A receptor expressed CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50320378(8-(4-(2,4-difluorophenethyl)piperidin-1-ylsulfonyl...)
Affinity DataKi:  2.10nMAssay Description:Displacement of [3H]- ketanserin from human 5HT2A receptor expressed CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50185780((4-(2,4-difluorophenethyl)piperidin-1-yl)(2-fluoro...)
Affinity DataKi:  3.90nMAssay Description:Displacement of [3H]- ketanserin from human 5HT2A receptor expressed CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50320375((E)-1-(2-(4-(4-fluorostyryl)phenylsulfonyl)phenyl)...)
Affinity DataKi:  7nMAssay Description:Displacement of [3H]mesulergine from human 5HT2C receptor expressed CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50095027((2,3-Dimethoxy-phenyl)-{1-[2-(4-fluoro-phenyl)-eth...)
Affinity DataKi:  13nMAssay Description:Displacement of [3H]mesulergine from human 5HT2C receptor expressed CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50320373((E)-3-(4-(2,4-difluorostyryl)phenylsulfonyl)benzam...)
Affinity DataKi:  21nMAssay Description:Displacement of [3H]mesulergine from human 5HT2C receptor expressed CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50108699(1-(2,4-difluorophenethyl)-4-(4-fluorophenylsulfony...)
Affinity DataKi:  39nMAssay Description:Displacement of [3H]mesulergine from human 5HT2C receptor expressed CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50320374((E)-4-(4-(2,4-difluorostyryl)phenylsulfonyl)benzam...)
Affinity DataKi:  41nMAssay Description:Displacement of [3H]mesulergine from human 5HT2C receptor expressed CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50320376((S,E)-1-(2-(4-(4-fluorostyryl)phenylsulfonyl)pheny...)
Affinity DataKi:  47nMAssay Description:Displacement of [3H]mesulergine from human 5HT2C receptor expressed CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50320370((E)-2,4-difluoro-1-(4-(phenylsulfonyl)styryl)benze...)
Affinity DataKi:  65nMAssay Description:Displacement of [3H]mesulergine from human 5HT2C receptor expressed CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50169842(1-[2-(2,4-Difluoro-phenyl)-ethyl]-4-fluoro-4-(4-fl...)
Affinity DataKi:  69nMAssay Description:Displacement of [3H]mesulergine from human 5HT2C receptor expressed CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50185780((4-(2,4-difluorophenethyl)piperidin-1-yl)(2-fluoro...)
Affinity DataKi:  100nMAssay Description:Displacement of [3H]mesulergine from human 5HT2C receptor expressed CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50320372((E)-2-(4-(2,4-difluorostyryl)phenylsulfonyl)benzam...)
Affinity DataKi:  127nMAssay Description:Displacement of [3H]mesulergine from human 5HT2C receptor expressed CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50320378(8-(4-(2,4-difluorophenethyl)piperidin-1-ylsulfonyl...)
Affinity DataKi:  184nMAssay Description:Displacement of [3H]mesulergine from human 5HT2C receptor expressed CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50320371(2,4-difluoro-1-(4-(phenylsulfonyl)phenethyl)benzen...)
Affinity DataKi:  526nMAssay Description:Displacement of [3H]mesulergine from human 5HT2C receptor expressed CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50108699(1-(2,4-difluorophenethyl)-4-(4-fluorophenylsulfony...)
Affinity DataKi:  710nMAssay Description:Displacement of [3H]-dofetilide from human ERG receptor expressed HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50095027((2,3-Dimethoxy-phenyl)-{1-[2-(4-fluoro-phenyl)-eth...)
Affinity DataKi:  1.10E+3nMAssay Description:Displacement of [3H]-dofetilide from human ERG receptor expressed HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50320375((E)-1-(2-(4-(4-fluorostyryl)phenylsulfonyl)phenyl)...)
Affinity DataKi:  4.00E+3nMAssay Description:Displacement of [3H]-dofetilide from human ERG receptor expressed HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50320370((E)-2,4-difluoro-1-(4-(phenylsulfonyl)styryl)benze...)
Affinity DataKi:  4.34E+3nMAssay Description:Displacement of [3H]-dofetilide from human ERG receptor expressed HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50169842(1-[2-(2,4-Difluoro-phenyl)-ethyl]-4-fluoro-4-(4-fl...)
Affinity DataKi:  5.56E+3nMAssay Description:Displacement of [3H]-dofetilide from human ERG receptor expressed HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50320374((E)-4-(4-(2,4-difluorostyryl)phenylsulfonyl)benzam...)
Affinity DataKi:  7.92E+3nMAssay Description:Displacement of [3H]-dofetilide from human ERG receptor expressed HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50320376((S,E)-1-(2-(4-(4-fluorostyryl)phenylsulfonyl)pheny...)
Affinity DataKi:  8.25E+3nMAssay Description:Displacement of [3H]-dofetilide from human ERG receptor expressed HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50320373((E)-3-(4-(2,4-difluorostyryl)phenylsulfonyl)benzam...)
Affinity DataKi: >9.00E+3nMAssay Description:Displacement of [3H]-dofetilide from human ERG receptor expressed HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50320372((E)-2-(4-(2,4-difluorostyryl)phenylsulfonyl)benzam...)
Affinity DataKi: >9.00E+3nMAssay Description:Displacement of [3H]-dofetilide from human ERG receptor expressed HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50320371(2,4-difluoro-1-(4-(phenylsulfonyl)phenethyl)benzen...)
Affinity DataKi: >9.00E+3nMAssay Description:Displacement of [3H]-dofetilide from human ERG receptor expressed HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50185780((4-(2,4-difluorophenethyl)piperidin-1-yl)(2-fluoro...)
Affinity DataKi: >9.00E+3nMAssay Description:Displacement of [3H]-dofetilide from human ERG receptor expressed HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50320378(8-(4-(2,4-difluorophenethyl)piperidin-1-ylsulfonyl...)
Affinity DataKi: >9.00E+3nMAssay Description:Displacement of [3H]-dofetilide from human ERG receptor expressed HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed