Compile Data Set for Download or QSAR
Report error Found 49 Enz. Inhib. hit(s) with all data for entry = 50039181
TargetVitamin D3 receptor(Human)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50200182((1S,3R,5Z,7E)-9,10-secocholesta-5,7,10(19)-triene-...)
Affinity DataIC50: 13nMAssay Description:Binding affinity to VDR ligand binding domain by fluorescence polarization competition assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVitamin D3 receptor(Human)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50320744(N-((R)-5-((1R,3aS,7aR,E)-4-(2-((3R,5R)-3,5-Dihydro...)
Affinity DataIC50: 14nMAssay Description:Binding affinity to VDR ligand binding domain by fluorescence polarization competition assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVitamin D3 receptor(Human)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50320746(N-((R)-5-((1R,3aS,7aR,E)-4-(2-((3R,5R)-3,5-Dihydro...)
Affinity DataIC50: 15nMAssay Description:Binding affinity to VDR ligand binding domain by fluorescence polarization competition assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVitamin D3 receptor(Human)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50320745(N-((R)-5-((1R,3aS,7aR,E)-4-(2-((3R,5R)-3,5-Dihydro...)
Affinity DataIC50: 29nMAssay Description:Binding affinity to VDR ligand binding domain by fluorescence polarization competition assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVitamin D3 receptor(Human)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50320738(N-((R)-5-((1R,3aS,7aR,E)-4-(2-((3R,5R)-3,5-Dihydro...)
Affinity DataIC50: 36nMAssay Description:Binding affinity to VDR ligand binding domain by fluorescence polarization competition assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVitamin D3 receptor(Human)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50320735(triciferol | CHEMBL1164992)
Affinity DataIC50: 87nMAssay Description:Binding affinity to VDR ligand binding domain by fluorescence polarization competition assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 3(Human)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 150nMAssay Description:Inhibition of HDAC3 after 10 mins by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVitamin D3 receptor(Human)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50320737((R)-N-(2-Aminophenyl)-6-((1R,3aS,7aR,E)-4-(2-((3R,...)
Affinity DataIC50: 185nMAssay Description:Binding affinity to VDR ligand binding domain by fluorescence polarization competition assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVitamin D3 receptor(Human)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50320748(N-((R)-5-((1R,3aS,7aR,E)-4-(2-((3R,5R)-3,5-Dihydro...)
Affinity DataIC50: 196nMAssay Description:Binding affinity to VDR ligand binding domain by fluorescence polarization competition assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 2(Human)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 210nMAssay Description:Inhibition of HDAC2 after 10 mins by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetVitamin D3 receptor(Human)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50320742(N-((R)-4-((1R,3aS,7aR,E)-4-(2-((3R,5R)-3,5-Dihydro...)
Affinity DataIC50: 213nMAssay Description:Binding affinity to VDR ligand binding domain by fluorescence polarization competition assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVitamin D3 receptor(Human)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50320736((R)-5-((1R,3aS,7aR,E)-4-(2-((3R,5R)-3,5-Dihydroxyc...)
Affinity DataIC50: 248nMAssay Description:Binding affinity to VDR ligand binding domain by fluorescence polarization competition assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVitamin D3 receptor(Human)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50320747(N-((R)-5-((1R,3aS,7aR,E)-4-(2-((3R,5R)-3,5-Dihydro...)
Affinity DataIC50: 280nMAssay Description:Binding affinity to VDR ligand binding domain by fluorescence polarization competition assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVitamin D3 receptor(Human)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50320743(N-((R)-5-((1R,3aS,7aR,E)-4-(2-((3R,5R)-3,5-Dihydro...)
Affinity DataIC50: 321nMAssay Description:Binding affinity to VDR ligand binding domain by fluorescence polarization competition assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 6(Human)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 350nMAssay Description:Inhibition of HDAC6 after 10 mins by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVitamin D3 receptor(Human)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50320741((R)-N-(2-Aminophenyl)-5-((1R,3aS,7aR,E)-4-(2-((3R,...)
Affinity DataIC50: 524nMAssay Description:Binding affinity to VDR ligand binding domain by fluorescence polarization competition assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 6(Human)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50320735(triciferol | CHEMBL1164992)
Affinity DataIC50: 580nMAssay Description:Inhibition of HDAC6 after 10 mins by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 6(Human)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50320738(N-((R)-5-((1R,3aS,7aR,E)-4-(2-((3R,5R)-3,5-Dihydro...)
Affinity DataIC50: 1.75E+3nMAssay Description:Inhibition of HDAC6 after 10 mins by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 6(Human)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50320736((R)-5-((1R,3aS,7aR,E)-4-(2-((3R,5R)-3,5-Dihydroxyc...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of HDAC6 after 10 mins by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 3(Human)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50320740((R)-5-((1R,3aS,7aR,E)-4-(2-((3R,5R)-3,5-Dihydroxyc...)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of HDAC3 after 10 mins by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 6(Human)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50320740((R)-5-((1R,3aS,7aR,E)-4-(2-((3R,5R)-3,5-Dihydroxyc...)
Affinity DataIC50: 9.30E+3nMAssay Description:Inhibition of HDAC6 after 10 mins by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 2(Human)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50320735(triciferol | CHEMBL1164992)
Affinity DataIC50: 1.04E+4nMAssay Description:Inhibition of HDAC2 after 10 mins by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 3(Human)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50320735(triciferol | CHEMBL1164992)
Affinity DataIC50: 1.33E+4nMAssay Description:Inhibition of HDAC3 after 10 mins by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 3(Human)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50320736((R)-5-((1R,3aS,7aR,E)-4-(2-((3R,5R)-3,5-Dihydroxyc...)
Affinity DataIC50: 1.45E+4nMAssay Description:Inhibition of HDAC3 after 10 mins by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 2(Human)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50320736((R)-5-((1R,3aS,7aR,E)-4-(2-((3R,5R)-3,5-Dihydroxyc...)
Affinity DataIC50: 1.65E+4nMAssay Description:Inhibition of HDAC2 after 10 mins by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 6(Human)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50320748(N-((R)-5-((1R,3aS,7aR,E)-4-(2-((3R,5R)-3,5-Dihydro...)
Affinity DataIC50: 3.16E+4nMAssay Description:Inhibition of HDAC6 after 10 mins by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 3(Human)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50320738(N-((R)-5-((1R,3aS,7aR,E)-4-(2-((3R,5R)-3,5-Dihydro...)
Affinity DataIC50: 3.23E+4nMAssay Description:Inhibition of HDAC3 after 10 mins by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 3(Human)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50320739((R)-7-((1R,3aS,7aR,E)-4-(2-((3R,5R)-3,5-Dihydroxyc...)
Affinity DataIC50: 3.60E+4nMAssay Description:Inhibition of HDAC3 after 10 mins by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 6(Human)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50320747(N-((R)-5-((1R,3aS,7aR,E)-4-(2-((3R,5R)-3,5-Dihydro...)
Affinity DataIC50: 5.04E+4nMAssay Description:Inhibition of HDAC6 after 10 mins by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 6(Human)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50320739((R)-7-((1R,3aS,7aR,E)-4-(2-((3R,5R)-3,5-Dihydroxyc...)
Affinity DataIC50: 6.40E+4nMAssay Description:Inhibition of HDAC6 after 10 mins by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 6(Human)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50320742(N-((R)-4-((1R,3aS,7aR,E)-4-(2-((3R,5R)-3,5-Dihydro...)
Affinity DataIC50: 7.13E+4nMAssay Description:Inhibition of HDAC6 after 10 mins by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 6(Human)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50320737((R)-N-(2-Aminophenyl)-6-((1R,3aS,7aR,E)-4-(2-((3R,...)
Affinity DataIC50: 8.11E+4nMAssay Description:Inhibition of HDAC6 after 10 mins by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 2(Human)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50320739((R)-7-((1R,3aS,7aR,E)-4-(2-((3R,5R)-3,5-Dihydroxyc...)
Affinity DataIC50: 9.04E+4nMAssay Description:Inhibition of HDAC2 after 10 mins by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 2(Human)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50320738(N-((R)-5-((1R,3aS,7aR,E)-4-(2-((3R,5R)-3,5-Dihydro...)
Affinity DataIC50: 9.63E+4nMAssay Description:Inhibition of HDAC2 after 10 mins by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 6(Human)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50320745(N-((R)-5-((1R,3aS,7aR,E)-4-(2-((3R,5R)-3,5-Dihydro...)
Affinity DataIC50: 1.01E+5nMAssay Description:Inhibition of HDAC6 after 10 mins by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 3(Human)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50320737((R)-N-(2-Aminophenyl)-6-((1R,3aS,7aR,E)-4-(2-((3R,...)
Affinity DataIC50: 1.04E+5nMAssay Description:Inhibition of HDAC3 after 10 mins by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 6(Human)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50320744(N-((R)-5-((1R,3aS,7aR,E)-4-(2-((3R,5R)-3,5-Dihydro...)
Affinity DataIC50: 1.53E+5nMAssay Description:Inhibition of HDAC6 after 10 mins by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 2(Human)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50320737((R)-N-(2-Aminophenyl)-6-((1R,3aS,7aR,E)-4-(2-((3R,...)
Affinity DataIC50: 1.89E+5nMAssay Description:Inhibition of HDAC2 after 10 mins by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 6(Human)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50320743(N-((R)-5-((1R,3aS,7aR,E)-4-(2-((3R,5R)-3,5-Dihydro...)
Affinity DataIC50: 1.91E+5nMAssay Description:Inhibition of HDAC6 after 10 mins by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 6(Human)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50320746(N-((R)-5-((1R,3aS,7aR,E)-4-(2-((3R,5R)-3,5-Dihydro...)
Affinity DataIC50: 2.93E+5nMAssay Description:Inhibition of HDAC6 after 10 mins by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 6(Human)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50320741((R)-N-(2-Aminophenyl)-5-((1R,3aS,7aR,E)-4-(2-((3R,...)
Affinity DataIC50: 3.30E+5nMAssay Description:Inhibition of HDAC6 after 10 mins by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 3(Human)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50320741((R)-N-(2-Aminophenyl)-5-((1R,3aS,7aR,E)-4-(2-((3R,...)
Affinity DataIC50: 4.60E+5nMAssay Description:Inhibition of HDAC3 after 10 mins by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 3(Human)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50320747(N-((R)-5-((1R,3aS,7aR,E)-4-(2-((3R,5R)-3,5-Dihydro...)
Affinity DataIC50: 4.70E+5nMAssay Description:Inhibition of HDAC3 after 10 mins by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 3(Human)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50320746(N-((R)-5-((1R,3aS,7aR,E)-4-(2-((3R,5R)-3,5-Dihydro...)
Affinity DataIC50: 5.08E+5nMAssay Description:Inhibition of HDAC3 after 10 mins by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 3(Human)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50320748(N-((R)-5-((1R,3aS,7aR,E)-4-(2-((3R,5R)-3,5-Dihydro...)
Affinity DataIC50: 6.05E+5nMAssay Description:Inhibition of HDAC3 after 10 mins by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 3(Human)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50320744(N-((R)-5-((1R,3aS,7aR,E)-4-(2-((3R,5R)-3,5-Dihydro...)
Affinity DataIC50: 6.95E+5nMAssay Description:Inhibition of HDAC3 after 10 mins by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 3(Human)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50320743(N-((R)-5-((1R,3aS,7aR,E)-4-(2-((3R,5R)-3,5-Dihydro...)
Affinity DataIC50: 7.18E+5nMAssay Description:Inhibition of HDAC3 after 10 mins by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 3(Human)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50320745(N-((R)-5-((1R,3aS,7aR,E)-4-(2-((3R,5R)-3,5-Dihydro...)
Affinity DataIC50: 7.25E+5nMAssay Description:Inhibition of HDAC3 after 10 mins by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 3(Human)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50320742(N-((R)-4-((1R,3aS,7aR,E)-4-(2-((3R,5R)-3,5-Dihydro...)
Affinity DataIC50: 7.30E+5nMAssay Description:Inhibition of HDAC3 after 10 mins by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed