Compile Data Set for Download or QSAR
Report error Found 53 Enz. Inhib. hit(s) with all data for entry = 50039155
TargetAromatase(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM7461(5,7-dihydroxy-2-phenyl-4H-chromen-4-one | cid_5281...)
Affinity DataIC50: 1nMAssay Description:Inhibition of human placental microsome CYP19More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50318410(3,4-bis(3,4-dimethoxyphenyl)furan-2(5H)-one | CHEM...)
Affinity DataIC50: 1nMAssay Description:Inhibition of human placental microsome CYP19More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50378780((S)-VOROZOLE)
Affinity DataIC50: 1.38nMAssay Description:Inhibition of human placental microsome CYP19More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM31774(cid_2812 | CHEMBL104 | Canesten | Mycelex | Lotrim...)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of human placental microsome CYP19More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50077323(7-hydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one | 7...)
Affinity DataIC50: 2nMAssay Description:Inhibition of human placental microsome CYP19More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50318411(11beta,13-Dihydro-10-epi-8-deoxycumam-brin B | CHE...)
Affinity DataIC50: 2nMAssay Description:Inhibition of human placental microsome CYP19More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50253941(3-((1H-imidazol-1-yl)(4-nitrophenyl)methyl)-4H-chr...)
Affinity DataIC50: 2.30nMAssay Description:Inhibition of human placental microsome CYP19More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM23419(CHEMBL9352 | (2S)-5,7-dihydroxy-2-(4-hydroxyphenyl...)
Affinity DataIC50: 2.90nMAssay Description:Inhibition of human placental microsome CYP19More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50047260(4,4'-((1H-imidazol-1-yl)methylene)dibenzonitrile |...)
Affinity DataIC50: 3nMAssay Description:Inhibition of human placental microsome CYP19More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50318389(3-amino-2-((1,2-dihydropyridin-4-yl)methyl)-5-meth...)
Affinity DataIC50: 3.5nMAssay Description:Inhibition of human placental microsome CYP19More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM8611(CHEMBL468419 | 4-{5H,6H,7H,8H-imidazo[1,5-a]pyridi...)
Affinity DataIC50: 5nMAssay Description:Inhibition of human placental microsome CYP19More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50176808(6-((3-chlorophenyl)(1H-imidazol-1-yl)methyl)-1H-be...)
Affinity DataIC50: 5nMAssay Description:Inhibition of human placental microsome CYP19More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM9460(3-(4-aminophenyl)-3-ethyl-piperidine-2,6-dione | C...)
Affinity DataIC50: 5.20nMAssay Description:Inhibition of human placental microsome CYP19More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50318398((3R,4R)-4-benzyl-3-(3-hydroxybenzyl)dihydrofuran-2...)
Affinity DataIC50: 6nMAssay Description:Inhibition of human placental microsome CYP19More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50049177((3R,4R)-3,4-Bis-(3,4-dihydroxy-benzyl)-dihydro-fur...)
Affinity DataIC50: 6nMAssay Description:Inhibition of human placental microsome CYP19More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50318390(3-(3,4-dimethoxyphenyl)-4-(4-methoxyphenyl)furan-2...)
Affinity DataIC50: 6.90nMAssay Description:Inhibition of human placental microsome CYP19More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50318395(10-Epi-8-deoxy-cumambrin B | CHEMBL1099308)
Affinity DataIC50: 7nMAssay Description:Inhibition of human placental microsome CYP19More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50028962(flavone | CHEMBL275638)
Affinity DataIC50: 8nMAssay Description:Inhibition of human placental microsome CYP19More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50077318(6,7-dihydroxy flavone | 6,7-Dihydroxy-2-phenyl-chr...)
Affinity DataIC50: 8.70nMAssay Description:Inhibition of human placental microsome CYP19More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50318391(1-(benzofuran-2-yl(4-chlorophenyl)methyl)-1H-imida...)
Affinity DataIC50: 8.80nMAssay Description:Inhibition of human placental microsome CYP19More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM9461(5,7-dihydroxy-3-(4-methoxyphenyl)-4H-chromen-4-one...)
Affinity DataIC50: 10.2nMAssay Description:Inhibition of human placental microsome CYP19More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM22372(Nordihydroguaiaretic Acid | CHEMBL313972 | 4-[(2S,...)
Affinity DataIC50: 11nMAssay Description:Inhibition of human placental microsome CYP19More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM13061(CHEMBL1444 | 4-[(4-cyanophenyl)(1H-1,2,4-triazol-1...)
Affinity DataIC50: 11.5nMAssay Description:Inhibition of human placental microsome CYP19More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM7460(2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-chromone;...)
Affinity DataIC50: 12nMAssay Description:Inhibition of human placental microsome CYP19More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50318399((R,S)-6-[1-(Imidazol-1-yl)-1phenylmethyl]-3-methyl...)
Affinity DataIC50: 13nMAssay Description:Inhibition of human placental microsome CYP19More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50318396(3-(3,4-dimethoxyphenyl)-4-(3,4,5-trimethoxyphenyl)...)
Affinity DataIC50: 13.7nMAssay Description:Inhibition of human placental microsome CYP19More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50318392((3aS,9aS,9bS)-6,9-Dimethyl-3-methylene-3,3a,4,5,9a...)
Affinity DataIC50: 15nMAssay Description:Inhibition of human placental microsome CYP19More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM10015(NSC719344 | arimidex | 2-[3-(1-cyano-1-methylethyl...)
Affinity DataIC50: 15nMAssay Description:Inhibition of human placental microsome CYP19More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50318393(3-formyl-5-hydroxy-4-(2-hydroxy-6-methylbenzoyl)be...)
Affinity DataIC50: 17.2nMAssay Description:Inhibition of human placental microsome CYP19More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50318397(3-formyl-4-(2-hydroxy-6-methylbenzoyl)-5-methoxy-N...)
Affinity DataIC50: 17.2nMAssay Description:Inhibition of human placental microsome CYP19More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50318400(9-Hydroxy-7,8-benzoflavone | CHEMBL1097042)
Affinity DataIC50: 20nMAssay Description:Inhibition of human placental microsome CYP19More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM26664(7-Hydroxy-flavone, 5a | 7-Hydroxyflavone, 11 | 7-h...)
Affinity DataIC50: 30.5nMAssay Description:Inhibition of human placental microsome CYP19More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50318401(1-ethyl-3-((4-fluorophenyl)(1H-imidazol-1-yl)methy...)
Affinity DataIC50: 32nMAssay Description:Inhibition of human placental microsome CYP19More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50318402((Z)-2-(pyridin-3-ylmethylene)-3-(4-(trifluorometho...)
Affinity DataIC50: 40nMAssay Description:Inhibition of human placental microsome CYP19More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50318394(Ludartin | 6,8a-Dimethyl-3-methylene-3a,4,5,7,7a,8...)
Affinity DataIC50: 55nMAssay Description:Inhibition of human placental microsome CYP19More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM31768(Nizoral | CHEMBL295698 | Panfungol | Ketoconazole)
Affinity DataIC50: 60nMAssay Description:Inhibition of human placental microsome CYP19More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50035204(4-(6-methoxy-1a,2,3,7b-tetrahydro-1H-cyclopropa[a]...)
Affinity DataIC50: 61nMAssay Description:Inhibition of human placental microsome CYP19More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50014323(CHEMBL283196 | alpha-naphthoflavone | 2-PHENYL-4H-...)
Affinity DataIC50: 70nMAssay Description:Inhibition of human placental microsome CYP19More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50318403(3-((1H-imidazol-1-yl)methyl)-1-(4-fluorophenyl)-1H...)
Affinity DataIC50: 71.8nMAssay Description:Inhibition of human placental microsome CYP19More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM9465(1-(9-Phenyl-9H-fluoren-9-yl)-1H-imidazole | CHEMBL...)
Affinity DataIC50: 74nMAssay Description:Inhibition of human placental microsome CYP19More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM9911(3-phenyl-7-[(4-phenylphenyl)methoxy]-2-[(pyridin-4...)
Affinity DataIC50: 85nMAssay Description:Inhibition of human placental microsome CYP19More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50318404(3-((1H-imidazol-2-yl)(phenyl)methyl)-5-bromo-1-eth...)
Affinity DataIC50: 102nMAssay Description:Inhibition of human placental microsome CYP19More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50318405((Z)-6-(4-chlorophenyl)-7-(pyridin-3-ylmethylene)-6...)
Affinity DataIC50: 110nMAssay Description:Inhibition of human placental microsome CYP19More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50318407(N-[2-(4'-Nitrophenyl)ethyl]-imidazole | CHEMBL1098...)
Affinity DataIC50: 160nMAssay Description:Inhibition of human placental microsome CYP19More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50318406(1-[(7-Fluoronaphth-2-yl)methyl]-1H-imidazole | CHE...)
Affinity DataIC50: 160nMAssay Description:Inhibition of human placental microsome CYP19More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM10024(5-(1H-imidazol-1-ylmethyl)-5,6,7,8-tetrahydroquino...)
Affinity DataIC50: 160nMAssay Description:Inhibition of human placental microsome CYP19More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50318408(5,7-dihydroxy-2-(4-hydroxyphenyl)-8-(4-methylpent-...)
Affinity DataIC50: 200nMAssay Description:Inhibition of human placental microsome CYP19More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50009606(5-Hydroxy-2-pyridin-4-ylmethyl-3,4-dihydro-2H-naph...)
Affinity DataIC50: 200nMAssay Description:Inhibition of human placental microsome CYP19More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50070097(MR-20492 | (Z)-6-(4-chlorophenyl)-7-(pyridin-4-ylm...)
Affinity DataIC50: 200nMAssay Description:Inhibition of human placental microsome CYP19More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50318409(7-phenoxy-3-phenyl-2-(pyridin-3-ylmethylthio)chrom...)
Affinity DataIC50: 210nMAssay Description:Inhibition of human placental microsome CYP19More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
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